STRINGSTRING
ypiP ypiP lysC lysC serA serA yhfR yhfR dapG dapG asd asd BL01335 BL01335 BL01336 BL01336 bfmBC bfmBC yqhT yqhT gcvPB gcvPB gcvPA gcvPA gcvT gcvT BL01574 BL01574 pdhD pdhD BL01735 BL01735 yclM yclM thrCA thrCA BL02069 BL02069 thrB thrB thrC thrC hom hom yutH yutH serC serC gcvH gcvH yusI yusI sdaAB sdaAB sdaAA sdaAA glxK glxK pssA pssA gbsB gbsB gbsA gbsA trpA trpA trpB trpB BL02887 BL02887 acoL acoL ilvA ilvA spx spx BL03435 BL03435 pgm pgm ykvY ykvY yvcT yvcT tdh tdh kbl kbl BL03733 BL03733 glyA glyA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ypiPConserved hypothetical protein. (208 aa)
lysCAspartokinase II alpha subunit and beta subunit; Belongs to the aspartokinase family. (409 aa)
serAPhosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa)
yhfRPutative Phosphoglycerate/bisphosphoglycerate mutase YhfR; Belongs to the phosphoglycerate mutase family. (190 aa)
dapGAspartokinase I (alpha and beta subunits); Belongs to the aspartokinase family. (404 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (346 aa)
BL01335Putative L-2,4-diaminobutyrate decarboxylase. (503 aa)
BL013364-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
bfmBCBranched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase). (473 aa)
yqhTPeptidase M24B, X-Pro dipeptidase YqhT. (353 aa)
gcvPBGlycine decarboxylase (subunit 2) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (485 aa)
gcvPAGlycine decarboxylase (subunit 1) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvTAminomethyltransferase (glycine cleavage system protein T); The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
BL01574Conserved protein YqgZ; Belongs to the ArsC family. (125 aa)
pdhDDihydrolipoamide dehydrogenase E3 subunit of both pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes. (470 aa)
BL01735Putative L-2,4-diaminobutyrate decarboxylase. (553 aa)
yclMAspartate kinase YclM; Belongs to the aspartokinase family. (453 aa)
thrCAThreonine synthase. (367 aa)
BL02069Putative alanine racemase. (368 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (306 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
homHomoserine dehydrogenase. (433 aa)
yutHConserved protein YutH. (336 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (357 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (127 aa)
yusIConserved hypothetical protein YusI; Belongs to the ArsC family. (118 aa)
sdaABL-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa)
sdaAAL-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. (300 aa)
glxKGlycerate kinase GlxK; Belongs to the glycerate kinase type-1 family. (376 aa)
pssAPhosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (178 aa)
gbsBAlcohol dehydrogenase. (402 aa)
gbsAGlycine betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
trpATryptophan synthase (alpha subunit); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa)
BL02887Putative aminoacid decarboxylase. (542 aa)
acoLAcetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase). (458 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
spxGlutaredoxin family protein Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (131 aa)
BL03435D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (316 aa)
pgmPhosphoglycerate mutase; Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. (511 aa)
ykvYPeptidase M24,putative metallopetidase. (364 aa)
yvcTProbable 2-ketogluconate reductase YvcT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
tdhThreonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (346 aa)
kbl2-amino-3-ketobutyrate CoA ligase (glycine acetyl transferase); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (391 aa)
BL03733Putative phosphatase; Belongs to the phosphoglycerate mutase family. (210 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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