STRINGSTRING
APT85782.1 APT85782.1 lysC lysC asd asd APT86030.1 APT86030.1 metXA metXA APT86209.1 APT86209.1 APT86246.1 APT86246.1 serC serC dcm dcm APT86613.1 APT86613.1 APT86680.1 APT86680.1 metK metK APT86949.1 APT86949.1 APT87163.1 APT87163.1 APT87223.1 APT87223.1 APT87319.1 APT87319.1 mdh mdh APT87394.1 APT87394.1 APT87440.1 APT87440.1 APT87521.1 APT87521.1 cysK cysK cysE cysE APT87702.1 APT87702.1 APT87722.1 APT87722.1 ldh ldh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APT85782.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (758 aa)
lysCAspartate kinase; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine; Belongs to the aspartokinase family. (421 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
APT86030.1S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (153 aa)
metXAHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (355 aa)
APT86209.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
APT86246.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
dcmCytosine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
APT86613.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
APT86680.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (410 aa)
APT86949.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (469 aa)
APT87163.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
APT87223.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
APT87319.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (320 aa)
APT87394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
APT87440.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
APT87521.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
cysKCysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
cysESerine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
APT87702.1Sulfultransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
APT87722.1Nucleosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
Your Current Organism:
Corynebacterium flavescens
NCBI taxonomy Id: 28028
Other names: ATCC 10340, C. flavescens, CCUG 28791, CIP 69.5, DSM 20296, IFO 14136, LMG 4046, LMG:4046, Microbacterium flavum , Mycobacterium flavum, NBRC 14136, NCCB 42012, NCIB 8707, NCIB:8707, NCIMB 8707
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