STRINGSTRING
KXO18204.1 KXO18204.1 KXO18059.1 KXO18059.1 kdsB kdsB KXO17983.1 KXO17983.1 KXO17427.1 KXO17427.1 KXO17428.1 KXO17428.1 KXO17429.1 KXO17429.1 KXO17454.1 KXO17454.1 KXO17464.1 KXO17464.1 KXO17320.1 KXO17320.1 KXO17321.1 KXO17321.1 KXO16093.1 KXO16093.1 miaA miaA KXO14676.1 KXO14676.1 miaA-2 miaA-2 KXO14680.1 KXO14680.1 lpxC lpxC lpxD lpxD KXO14683.1 KXO14683.1 KXO14690.1 KXO14690.1 KXO14691.1 KXO14691.1 KXO14692.1 KXO14692.1 lpxK lpxK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KXO18204.13-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (406 aa)
KXO18059.1KEGG: pmz:HMPREF0659_A6733 2.7e-71 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270; Psort location: Cytoplasmic, score: 9.97. (172 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
KXO17983.1lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
KXO17427.1Hypothetical protein; KEGG: acs:100561462 5.2e-08 galactoside 2-alpha-L-fucosyltransferase 2-like; K00718 galactoside 2-L-fucosyltransferase 1/2; Psort location: Cytoplasmic, score: 8.96. (270 aa)
KXO17428.1KEGG: pmz:HMPREF0659_A6393 8.1e-95 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 8.96. (298 aa)
KXO17429.1KEGG: pdn:HMPREF9137_0485 7.1e-96 glycosyltransferase group 1 family protein; Psort location: Cytoplasmic, score: 9.97. (381 aa)
KXO17454.1Heptosyltransferase; KEGG: gfo:GFO_3278 1.6e-57 RfaQ-like lipopolysaccharide core biosynthesis glycosyl transferase K01043; Psort location: Cytoplasmic, score: 8.96. (348 aa)
KXO17464.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (200 aa)
KXO17320.1KEGG: pmz:HMPREF0659_A5655 1.2e-141 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. (324 aa)
KXO17321.1KEGG: pmz:HMPREF0659_A5656 2.2e-110 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627; Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. (252 aa)
KXO16093.1KEGG: pmz:HMPREF0659_A5478 1.7e-110 putative acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase; K00677 UDP-N-acetylglucosamine acyltransferase; Psort location: Cytoplasmic, score: 9.97. (260 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (309 aa)
KXO14676.1Hypothetical protein. (159 aa)
miaA-2tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (310 aa)
KXO14680.1acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (257 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (461 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (346 aa)
KXO14683.1HD domain protein; KEGG: fba:FIC_01915 2.5e-84 deoxyguanosinetriphosphate triphosphohydrolase K06885; Psort location: Cytoplasmic, score: 8.96. (407 aa)
KXO14690.1PhoH family protein; KEGG: apb:SAR116_1589 2.4e-63 PhoH family protein K06217; Psort location: Cytoplasmic, score: 9.97. (317 aa)
KXO14691.1Hypothetical protein. (274 aa)
KXO14692.1Hypothetical protein. (41 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (393 aa)
Your Current Organism:
Prevotella bivia
NCBI taxonomy Id: 28125
Other names: ATCC 29303, Bacteroides bivius, CCUG 9557, CIP 105105, DSM 20514, JCM 6331, LMG 6452, LMG:6452, NCTC 11156, P. bivia, VPI 6822, strain 653C, strain JCVIHMP010
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