node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ICL1 | PAY32 | P41555 | Q99144 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.614 |
ICL1 | POX1 | P41555 | O74934 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 1. | 0.800 |
ICL1 | XPR2 | P41555 | P09230 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases. | 0.644 |
ICL1 | YALI0_F04095g | P41555 | Q6C2Y4 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.891 |
ICL1 | YALI0_F05962g | P41555 | Q6C2Q5 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acetyl-coenzyme A synthetase. | 0.839 |
LEU2 | URA3 | P18120 | Q12724 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 0.933 |
LEU2 | XPR2 | P18120 | P09230 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases. | 0.814 |
PAY32 | ICL1 | Q99144 | P41555 | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.614 |
PAY32 | POX1 | Q99144 | O74934 | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | Acyl-coenzyme A oxidase 1. | 0.870 |
PAY32 | YALI0_F04095g | Q99144 | Q6C2Y4 | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.705 |
POX1 | ICL1 | O74934 | P41555 | Acyl-coenzyme A oxidase 1. | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.800 |
POX1 | PAY32 | O74934 | Q99144 | Acyl-coenzyme A oxidase 1. | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.870 |
POX1 | URA3 | O74934 | Q12724 | Acyl-coenzyme A oxidase 1. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 0.648 |
POX1 | XPR2 | O74934 | P09230 | Acyl-coenzyme A oxidase 1. | Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases. | 0.543 |
POX1 | YALI0_F04095g | O74934 | Q6C2Y4 | Acyl-coenzyme A oxidase 1. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.412 |
POX1 | YALI0_F05962g | O74934 | Q6C2Q5 | Acyl-coenzyme A oxidase 1. | Acetyl-coenzyme A synthetase. | 0.954 |
TEF | YALI0_F04095g | O59949 | Q6C2Y4 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.501 |
TEF | YALI0_F05962g | O59949 | Q6C2Q5 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | Acetyl-coenzyme A synthetase. | 0.424 |
URA3 | LEU2 | Q12724 | P18120 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.933 |
URA3 | POX1 | Q12724 | O74934 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | Acyl-coenzyme A oxidase 1. | 0.648 |