STRINGSTRING
fgf2 fgf2 fgf10 fgf10 LOC107102211 LOC107102211 fndc3b fndc3b LOC107082377 LOC107082377 LOC107101656 LOC107101656 mapk1 mapk1 LOC107084657 LOC107084657 ANOS1 ANOS1 LOC107098202 LOC107098202 LOC107101186 LOC107101186 FGF6-2 FGF6-2 LOC107085894 LOC107085894 ENSCVAP00000011097 ENSCVAP00000011097 LOC107089165 LOC107089165 pik3ca pik3ca grb2 grb2 SRC SRC mknk2 mknk2 FGF6 FGF6 ENSCVAP00000008530 ENSCVAP00000008530 plcg1 plcg1 LOC107089939 LOC107089939 hras hras LOC107102581 LOC107102581 FGFRL1 FGFRL1 KRAS KRAS LOC107095138 LOC107095138 rps27a rps27a Fgf4 Fgf4 SPRED2 SPRED2 ENSCVAP00000000999 ENSCVAP00000000999 CSDE1 CSDE1 ppp2ca ppp2ca LOC107096942 LOC107096942 fgf20 fgf20 LOC107091370 LOC107091370 fndc3a fndc3a ppp2r1b ppp2r1b LOC107083535 LOC107083535 fgf23 fgf23 LOC107090307 LOC107090307 LOC107081801 LOC107081801 LOC107089793 LOC107089793 frs2 frs2 LOC107088237 LOC107088237 LOC107085946 LOC107085946 uba52 uba52 PIK3CA PIK3CA fgfrl1 fgfrl1 cbl cbl LOC107087777 LOC107087777 fgf22 fgf22 LOC107089396 LOC107089396 ENSCVAP00000022018 ENSCVAP00000022018 mknk1 mknk1 spred1 spred1 LOC107102110 LOC107102110 fgf3 fgf3 shc1 shc1 ENSCVAP00000019433 ENSCVAP00000019433 ENSCVAP00000018644 ENSCVAP00000018644 fgf5 fgf5 flrt3 flrt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
fndc3bFibronectin type III domain containing 3Ba. (1207 aa)
LOC107082377Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
LOC107101656Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (160 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
LOC107084657Serine/threonine-protein phosphatase. (309 aa)
ANOS1Anosmin 1. (670 aa)
LOC107098202Uncharacterized protein. (860 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC107085894Serine/threonine-protein phosphatase. (309 aa)
ENSCVAP00000011097Fibronectin leucine rich transmembrane protein 2. (658 aa)
LOC107089165Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
SRCTyrosine-protein kinase. (551 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSCVAP00000008530Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (183 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1310 aa)
LOC107089939Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (172 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC107102581Fibroblast growth factor receptor substrate 3. (607 aa)
FGFRL1Fibroblast growth factor receptor like 1. (503 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC107095138Zgc:55558. (187 aa)
rps27aRibosomal protein S27a. (181 aa)
Fgf4Fibroblast growth factor 4. (144 aa)
SPRED2Sprouty related EVH1 domain containing 2. (465 aa)
ENSCVAP00000000999Uncharacterized protein; Belongs to the heparin-binding growth factors family. (167 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (907 aa)
ppp2caSerine/threonine-protein phosphatase. (314 aa)
LOC107096942Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
LOC107091370Fibronectin type-III domain-containing protein. (682 aa)
fndc3aFibronectin type III domain containing 3A. (1234 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC107083535Cbl proto-oncogene C, E3 ubiquitin protein ligase. (566 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (276 aa)
LOC107090307Sprouty RTK signaling antagonist 2. (351 aa)
LOC107081801Fibroblast growth factor receptor. (831 aa)
LOC107089793Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
frs2Fibroblast growth factor receptor substrate 2b. (531 aa)
LOC107088237Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC107085946Anosmin 1b. (653 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1038 aa)
fgfrl1Fibroblast growth factor receptor like 1a. (488 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
LOC107087777Fibronectin type-III domain-containing protein. (729 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
LOC107089396PH domain-containing protein. (761 aa)
ENSCVAP00000022018Uncharacterized protein. (54 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (461 aa)
spred1Sprouty related EVH1 domain containing 1. (435 aa)
LOC107102110Fibronectin leucine rich transmembrane protein 2. (651 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (443 aa)
ENSCVAP00000019433Sprouty related EVH1 domain containing 2a. (400 aa)
ENSCVAP00000018644Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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