STRINGSTRING
KSV60602.1 KSV60602.1 KSV58656.1 KSV58656.1 KSV58628.1 KSV58628.1 KSV59105.1 KSV59105.1 KSV59589.1 KSV59589.1 KSV60715.1 KSV60715.1 KSV60652.1 KSV60652.1 leuA leuA KSV60734.1 KSV60734.1 KSV58202.1 KSV58202.1 leuD leuD leuC leuC KSV59805.1 KSV59805.1 KSV59863.1 KSV59863.1 ilvC ilvC KSV60571.1 KSV60571.1 KSV57505.1 KSV57505.1 KSV57441.1 KSV57441.1 ilvD ilvD leuB leuB KSV57660.1 KSV57660.1 KSV57872.1 KSV57872.1 KSV60606.1 KSV60606.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KSV60602.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (403 aa)
KSV58656.1Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
KSV58628.1Replication initiator protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
KSV59105.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
KSV59589.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
KSV60715.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
KSV60652.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (553 aa)
KSV60734.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
KSV58202.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (161 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (421 aa)
KSV59805.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
KSV59863.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
KSV60571.1Replication initiator protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
KSV57505.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (610 aa)
KSV57441.1Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (553 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
KSV57660.1Aconitase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
KSV57872.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KSV60606.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (362 aa)
Your Current Organism:
Acetivibrio ethanolgignens
NCBI taxonomy Id: 290052
Other names: A. ethanolgignens, ATCC 33324, Acetivibrio ethanoligignens, DSM 3005, LMG 7055, LMG:7055, strain 77-6
Server load: low (18%) [HD]