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| | COX1 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa) |
| | COX3 | Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) |
| | IL6 | Interleukin-6. (189 aa) |
| | COX8A | Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa) |
| | COX4I2 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1. (171 aa) |
| | BAX | Apoptosis regulator BAX. (221 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | COX7B2 | Cytochrome c oxidase subunit 7B2, mitochondrial. (81 aa) |
| | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (56 aa) |
| | GSK3A | Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (417 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) |
| | COX7C | Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa) |
| | COX5A | Cytochrome c oxidase subunit 5A, mitochondrial. (145 aa) |
| | SREBF1 | LOW QUALITY PROTEIN: sterol regulatory element-binding protein 1. (230 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | LOC103671028 | Cytochrome c oxidase subunit 8B, mitochondrial-like. (70 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (862 aa) |
| | ADIPOR1 | Adiponectin receptor protein 1. (375 aa) |
| | MLXIP | MLX-interacting protein. (882 aa) |
| | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa) |
| | LOC103677394 | Transforming growth factor beta-1. (299 aa) |
| | NDUFS4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (182 aa) |
| | NDUFS7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1; Belongs to the complex I 20 kDa subunit family. (294 aa) |
| | NDUFB6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. (97 aa) |
| | LOC103681641 | Cytochrome b-c1 complex subunit 10. (62 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa) |
| | NDUFA13 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (161 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X2. (279 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (150 aa) |
| | TNFRSF1A | LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 1A. (507 aa) |
| | UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (500 aa) |
| | NDUFB5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1. (189 aa) |
| | COX4I1 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (219 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (963 aa) |
| | LEPR | Leptin receptor isoform X1. (1166 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (331 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (244 aa) |
| | NDUFS3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (310 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial isoform X1; Belongs to the peptidase M16 family. (453 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (561 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2. (251 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase 11. (281 aa) |
| | NDUFB11 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (142 aa) |
| | CYP2E1 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (494 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | RELA | Transcription factor p65. (585 aa) |
| | NDUFA11 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa) |
| | NDUFA3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (84 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) |
| | NDUFC2 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 subunit C2. (97 aa) |
| | LOC103671191 | Cytochrome c oxidase subunit 5B, mitochondrial. (129 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (519 aa) |
| | ADIPOR2 | Adiponectin receptor protein 2. (386 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) |
| | COX7A2L | Cytochrome c oxidase subunit 7A-related protein, mitochondrial. (114 aa) |
| | NDUFS8 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (205 aa) |
| | NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (107 aa) |
| | COX7A2 | LOW QUALITY PROTEIN: uncharacterized protein LOC103657485. (83 aa) |
| | CDC42 | Cell division control protein 42 homolog isoform X1. (191 aa) |
| | MLXIPL | Carbohydrate-responsive element-binding protein. (642 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1375 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (447 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | COX6A2 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | NDUFA7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (177 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa) |
| | NDUFA9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial isoform X1. (416 aa) |
| | NDUFC1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) |
| | NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | XBP1 | LOW QUALITY PROTEIN: X-box-binding protein 1. (211 aa) |
| | LOC103663786 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (95 aa) |
| | LOC103661483 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) |
| | UQCR10 | Ubiquinol-cytochrome c reductase, complex III subunit X. (64 aa) |
| | COX6C | Cytochrome C oxidase subunit 6C. (75 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (1029 aa) |
| | UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) |
| | LOC103675819 | Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa) |
| | NDUFV2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (249 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3. (491 aa) |
| | NDUFA4L2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (113 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha isoform X1. (468 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (180 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (520 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (269 aa) |
| | LOC103682512 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (165 aa) |
| | NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Belongs to the complex I LYR family. (147 aa) |
| | LOC103678327 | Cytochrome c oxidase subunit 6A, mitochondrial. (111 aa) |
| | CYC1 | Cytochrome c1, heme protein, mitochondrial. (266 aa) |
| | COX7A1 | Cytochrome c oxidase subunit 7A1, mitochondrial. (85 aa) |
| | NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa) |
| | NDUFB3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (97 aa) |
| | CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) |
| | NDUFA4 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4. (82 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (390 aa) |
| | NDUFB10 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (165 aa) |
| | NDUFB9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (234 aa) |
| | NDUFS1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (660 aa) |
| | NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial. (196 aa) |
| | LOC103657024 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1-like. (66 aa) |
| | SDHC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa) |
| | PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X2; Belongs to the complex I 49 kDa subunit family. (436 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1768 aa) |
| | CASP7 | Caspase-7; Belongs to the peptidase C14A family. (301 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LOC103680303 | Uncharacterized protein LOC103680303. (101 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (514 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (460 aa) |
| | MLX | Max-like protein X. (288 aa) |
| | NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | NDUFV3 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial. (469 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
