STRINGSTRING
AOI81191.1 AOI81191.1 cyaY cyaY AOI81270.1 AOI81270.1 gltD gltD AOI81392.1 AOI81392.1 erpA erpA AOI81532.1 AOI81532.1 AOI81566.1 AOI81566.1 AOI81845.1 AOI81845.1 AOI81888.1 AOI81888.1 AOI81903.1 AOI81903.1 AOI81910.1 AOI81910.1 mobA mobA moaA moaA fadH fadH tusA tusA AOI82720.1 AOI82720.1 AOI82721.1 AOI82721.1 AOI82722.1 AOI82722.1 moaD moaD AOI82724.1 AOI82724.1 iscX iscX fdx fdx hscA hscA hscB hscB iscA iscA iscU iscU iscS_2 iscS_2 iscR iscR AOI83030.1 AOI83030.1 ascD ascD moaC moaC fdhD fdhD moeB_2 moeB_2 AOI83801.1 AOI83801.1 AOI87009.1 AOI87009.1 AOI84608.1 AOI84608.1 AOI84833.1 AOI84833.1 iscS_1 iscS_1 fadH-2 fadH-2 AOI85050.1 AOI85050.1 potA_2 potA_2 modB_1 modB_1 ModA ModA AOI85168.1 AOI85168.1 fdnG fdnG fdnH fdnH fdoI fdoI fdhE fdhE selA selA SelB SelB AOI85765.1 AOI85765.1 nirD nirD AOI85767.1 AOI85767.1 AOI85768.1 AOI85768.1 AOI85830.1 AOI85830.1 AOI86224.1 AOI86224.1 selD selD AOI86923.1 AOI86923.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOI81191.1Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; Derived by automated computational analysis using gene prediction method: Protein Homology. (1196 aa)
cyaYIron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (108 aa)
AOI81270.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1567 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
AOI81392.1Molybdopterin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (691 aa)
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. (123 aa)
AOI81532.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (539 aa)
AOI81566.1Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family. (402 aa)
AOI81845.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
AOI81888.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AOI81903.1Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (107 aa)
AOI81910.1Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (432 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (205 aa)
moaACyclic pyranopterin phosphate synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (370 aa)
fadHNADPH-dependent 2,4-dienoyl-CoA reductase; Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (674 aa)
tusAResponse regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (75 aa)
AOI82720.1Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
AOI82721.1Globin; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
AOI82722.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
moaDMolybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
AOI82724.1Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (415 aa)
iscXFe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. (69 aa)
fdx2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
hscAMolecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (622 aa)
hscBCo-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (175 aa)
iscAIron-sulfur cluster assembly protein IscA; Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. (107 aa)
iscUScaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (135 aa)
iscS_2Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (407 aa)
iscRRrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AOI83030.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
ascDCDP-6-deoxy-delta-3,4-glucoseen reductase; Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
moaCCyclic pyranopterin monophosphate synthase accessory protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (162 aa)
fdhDFormate dehydrogenase accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (278 aa)
moeB_2Molybdopterin biosynthesis protein MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AOI83801.1Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1190 aa)
AOI87009.1Molybdenum ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AOI84608.1Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
AOI84833.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
iscS_1Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (403 aa)
fadH-2NADPH-dependent 2,4-dienoyl-CoA reductase; Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (677 aa)
AOI85050.1Molybdenum-dependent transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
potA_2ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
modB_1Molybdenum ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (225 aa)
ModAMolybdate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AOI85168.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
fdnGFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (810 aa)
fdnHFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
fdoIFormate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
fdhEFormate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (316 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (479 aa)
SelBTranslation elongation factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
AOI85765.1Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1395 aa)
nirDNitrite reductase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
AOI85767.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (865 aa)
AOI85768.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
AOI85830.1CbbBc protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (774 aa)
AOI86224.1Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (357 aa)
AOI86923.1Molybdenum cofactor sulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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