STRINGSTRING
PGUG_00055 PGUG_00055 PGUG_00080 PGUG_00080 PGUG_00102 PGUG_00102 PGUG_00190 PGUG_00190 ARG2 ARG2 PGUG_00207 PGUG_00207 PGUG_00240 PGUG_00240 PGUG_00255 PGUG_00255 PGUG_00294 PGUG_00294 PGUG_00307 PGUG_00307 DQD1 DQD1 PGUG_00476 PGUG_00476 PGUG_00514 PGUG_00514 PGUG_00520 PGUG_00520 PGUG_00546 PGUG_00546 PGUG_00676 PGUG_00676 PGUG_00716 PGUG_00716 PGUG_00730 PGUG_00730 PGUG_00951 PGUG_00951 PGUG_01002 PGUG_01002 PGUG_01023 PGUG_01023 PGUG_01035 PGUG_01035 PGUG_01083 PGUG_01083 PGUG_01119 PGUG_01119 PGUG_01126 PGUG_01126 PGUG_01147 PGUG_01147 PGUG_01282 PGUG_01282 PGUG_01317 PGUG_01317 PGUG_01364 PGUG_01364 PGUG_01379 PGUG_01379 PGUG_01382 PGUG_01382 PGUG_01405 PGUG_01405 PGUG_01417 PGUG_01417 PGUG_01420 PGUG_01420 PGUG_01480 PGUG_01480 PGUG_01505 PGUG_01505 PGUG_01529 PGUG_01529 PGUG_01622 PGUG_01622 PGUG_01631 PGUG_01631 PGUG_01677 PGUG_01677 PGUG_01716 PGUG_01716 PGUG_01763 PGUG_01763 PGUG_01797 PGUG_01797 PGUG_01843 PGUG_01843 RKI1 RKI1 PGUG_02052 PGUG_02052 PGUG_02075 PGUG_02075 PGUG_02078 PGUG_02078 PGUG_02101 PGUG_02101 PGUG_02118 PGUG_02118 PGUG_02164 PGUG_02164 PGUG_02175 PGUG_02175 PGUG_02249 PGUG_02249 PGUG_02270 PGUG_02270 PGUG_02272 PGUG_02272 PGUG_02360 PGUG_02360 PGUG_02400 PGUG_02400 PGUG_02458 PGUG_02458 PGUG_02477 PGUG_02477 PGUG_02577 PGUG_02577 PGUG_02603 PGUG_02603 PGUG_02716 PGUG_02716 PGUG_02805 PGUG_02805 PGUG_02910 PGUG_02910 PGUG_03003 PGUG_03003 PGUG_03026 PGUG_03026 PGUG_03068 PGUG_03068 PGUG_03146 PGUG_03146 PGUG_03168 PGUG_03168 PGUG_03301 PGUG_03301 PGUG_03416 PGUG_03416 PGUG_03480 PGUG_03480 PGUG_03485 PGUG_03485 PGUG_03620 PGUG_03620 PGUG_03626 PGUG_03626 PGUG_03659 PGUG_03659 PGUG_03670 PGUG_03670 PGUG_03731 PGUG_03731 PGUG_03757 PGUG_03757 PGUG_03768 PGUG_03768 PGUG_03808 PGUG_03808 PGUG_03875 PGUG_03875 PGUG_03876 PGUG_03876 PGUG_03925 PGUG_03925 PGUG_03982 PGUG_03982 PGUG_04175 PGUG_04175 PGUG_04239 PGUG_04239 PGUG_04278 PGUG_04278 PGUG_04338 PGUG_04338 PGUG_04391 PGUG_04391 PGUG_04596 PGUG_04596 PGUG_04621 PGUG_04621 PGUG_04679 PGUG_04679 PGUG_04713 PGUG_04713 PGUG_04759 PGUG_04759 PGUG_04771 PGUG_04771 PGUG_04807 PGUG_04807 PGUG_04828 PGUG_04828 PGUG_04906 PGUG_04906 PGUG_04966 PGUG_04966 PGUG_05024 PGUG_05024 PGUG_05140 PGUG_05140 PGUG_05233 PGUG_05233 PGUG_05240 PGUG_05240 PGUG_05294 PGUG_05294 PGUG_05365 PGUG_05365 PGUG_05378 PGUG_05378 PGUG_05396 PGUG_05396 PGUG_05611 PGUG_05611 PGUG_05628 PGUG_05628 PGUG_05631 PGUG_05631
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_00055Uncharacterized protein. (416 aa)
PGUG_00080Beta_elim_lyase domain-containing protein. (369 aa)
PGUG_00102Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (779 aa)
PGUG_00190Phospho-2-dehydro-3-deoxyheptonate aldolase. (366 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (568 aa)
PGUG_00207Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (589 aa)
PGUG_00240Uncharacterized protein. (518 aa)
PGUG_00255Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (436 aa)
PGUG_00294Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
PGUG_00307Citrate synthase; Belongs to the citrate synthase family. (395 aa)
DQD1Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (146 aa)
PGUG_00476Chorismate mutase. (267 aa)
PGUG_00514Uncharacterized protein. (276 aa)
PGUG_00520Uncharacterized protein. (585 aa)
PGUG_00546DAHP_synth_1 domain-containing protein. (383 aa)
PGUG_00676Acetolactate synthase. (681 aa)
PGUG_00716Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
PGUG_00730Semialdhyde_dh domain-containing protein. (362 aa)
PGUG_00951Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
PGUG_01002Uncharacterized protein. (246 aa)
PGUG_01023Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (216 aa)
PGUG_01035Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (493 aa)
PGUG_01083Glutamine synthetase. (371 aa)
PGUG_01119PUA domain-containing protein. (420 aa)
PGUG_01126Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (293 aa)
PGUG_011473-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
PGUG_01282Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (677 aa)
PGUG_01317Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
PGUG_01364Aminotran_1_2 domain-containing protein. (400 aa)
PGUG_01379Uncharacterized protein. (437 aa)
PGUG_01382Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (276 aa)
PGUG_01405Triosephosphate isomerase. (248 aa)
PGUG_01417M20_dimer domain-containing protein. (400 aa)
PGUG_01420Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (674 aa)
PGUG_01480Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (447 aa)
PGUG_01505Histidine biosynthesis trifunctional protein. (844 aa)
PGUG_01529Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family. (404 aa)
PGUG_01622Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (798 aa)
PGUG_01631ACT domain-containing protein. (291 aa)
PGUG_01677Uncharacterized protein. (528 aa)
PGUG_01716D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (464 aa)
PGUG_01763Glutamine amidotransferase type-1 domain-containing protein. (496 aa)
PGUG_01797Pyruvate carboxyltransferase domain-containing protein. (524 aa)
PGUG_01843N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (880 aa)
RKI1Ribose-5-phosphate isomerase. (247 aa)
PGUG_02052Uncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (339 aa)
PGUG_02075Uncharacterized protein. (403 aa)
PGUG_02078Aminotran_1_2 domain-containing protein. (487 aa)
PGUG_02101Uncharacterized protein. (767 aa)
PGUG_02118Glutamine amidotransferase type-2 domain-containing protein. (573 aa)
PGUG_02164Aminotran_1_2 domain-containing protein. (502 aa)
PGUG_02175Pribosyltran_N domain-containing protein. (412 aa)
PGUG_02249Aldedh domain-containing protein. (438 aa)
PGUG_02270Threonine dehydratase. (583 aa)
PGUG_02272Aminotran_5 domain-containing protein. (296 aa)
PGUG_02360Beta_elim_lyase domain-containing protein. (375 aa)
PGUG_02400Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (438 aa)
PGUG_02458Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
PGUG_02477Ribose-phosphate pyrophosphokinase 1. (320 aa)
PGUG_02577Aminotran_1_2 domain-containing protein. (402 aa)
PGUG_02603Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
PGUG_02716DAHP_synth_1 domain-containing protein. (311 aa)
PGUG_02805Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (409 aa)
PGUG_02910Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (365 aa)
PGUG_03003Uncharacterized protein. (302 aa)
PGUG_03026ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (984 aa)
PGUG_03068Arginase; Belongs to the arginase family. (280 aa)
PGUG_03146Iso_dh domain-containing protein. (196 aa)
PGUG_03168PALP domain-containing protein. (427 aa)
PGUG_03301S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (382 aa)
PGUG_03416GHMP_kinases_N domain-containing protein. (350 aa)
PGUG_03480Chorismate synthase. (379 aa)
PGUG_03485Aspartate aminotransferase. (421 aa)
PGUG_03620Pyruvate carboxyltransferase domain-containing protein. (590 aa)
PGUG_03626PRAI domain-containing protein. (255 aa)
PGUG_03659Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (437 aa)
PGUG_036703-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. Belongs to the EPSP synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1210 aa)
PGUG_03731Pribosyltran_N domain-containing protein. (472 aa)
PGUG_03757Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
PGUG_03768Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
PGUG_03808Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (416 aa)
PGUG_03875Iso_dh domain-containing protein. (164 aa)
PGUG_03876Iso_dh domain-containing protein. (185 aa)
PGUG_03925Aminotran_1_2 domain-containing protein. (512 aa)
PGUG_03982Homoserine dehydrogenase. (385 aa)
PGUG_04175PALP domain-containing protein. (221 aa)
PGUG_04239Sacchrp_dh_C domain-containing protein. (327 aa)
PGUG_042783-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (382 aa)
PGUG_04338Glycos_transf_3 domain-containing protein. (256 aa)
PGUG_04391Enolase 1. (439 aa)
PGUG_04596Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PGUG_04621Aminotran_1_2 domain-containing protein. (478 aa)
PGUG_04679ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (952 aa)
PGUG_04713Uncharacterized protein. (584 aa)
PGUG_04759Carrier domain-containing protein. (1406 aa)
PGUG_04771AB hydrolase-1 domain-containing protein. (465 aa)
PGUG_04807Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (252 aa)
PGUG_04828PALP domain-containing protein. (472 aa)
PGUG_04906PALP domain-containing protein. (319 aa)
PGUG_04966PALP domain-containing protein. (355 aa)
PGUG_05024Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (287 aa)
PGUG_05140Uncharacterized protein; Belongs to the DapA family. (320 aa)
PGUG_05233Pribosyltran_N domain-containing protein. (323 aa)
PGUG_05240Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (291 aa)
PGUG_05294Aminotran_1_2 domain-containing protein. (426 aa)
PGUG_05365Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (370 aa)
PGUG_05378Aspartokinase. (528 aa)
PGUG_053961-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (267 aa)
PGUG_05611Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
PGUG_05628Argininosuccinate lyase. (464 aa)
PGUG_05631Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (312 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
Server load: low (12%) [HD]