STRINGSTRING
metG_4 metG_4 yugI_1 yugI_1 lysS lysS ssb ssb rpsA rpsA ligA ligA rlmCD rlmCD ugpC_1 ugpC_1 yugI_2 yugI_2 pheT_1 pheT_1 pheT_2 pheT_2 ruvA ruvA aspS aspS A21D_03188 A21D_03188 recO recO A21D_03214 A21D_03214 efp efp A21D_03359 A21D_03359 asnS asnS cspB_2 cspB_2 pnp pnp nusA nusA polC_2 polC_2 recG recG rsgA_2 rsgA_2 ugpC_2 ugpC_2 yuaF yuaF A21D_00025 A21D_00025 rnr rnr A21D_00251 A21D_00251 metG_1 metG_1 cspB_1 cspB_1 rho rho A21D_01023 A21D_01023 infA infA rpsQ rpsQ rplB rplB rpsL rpsL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metG_4Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (651 aa)
yugI_1Unannotated protein. (129 aa)
lysSUnannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (494 aa)
ssbUnannotated protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (166 aa)
rpsAUnannotated protein. (722 aa)
ligAUnannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (672 aa)
rlmCDUnannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (460 aa)
ugpC_1Unannotated protein; Belongs to the ABC transporter superfamily. (365 aa)
yugI_2Unannotated protein. (121 aa)
pheT_1Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (200 aa)
pheT_2Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (809 aa)
ruvAUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa)
aspSUnannotated protein; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (593 aa)
A21D_03188Unannotated protein. (444 aa)
recOUnannotated protein; Involved in DNA repair and RecF pathway recombination. (247 aa)
A21D_03214Unannotated protein. (209 aa)
efpUnannotated protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
A21D_03359Unannotated protein. (378 aa)
asnSUnannotated protein. (430 aa)
cspB_2Unannotated protein. (66 aa)
pnpUnannotated protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (704 aa)
nusAUnannotated protein; Participates in both transcription termination and antitermination. (365 aa)
polC_2Unannotated protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1428 aa)
recGUnannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (676 aa)
rsgA_2Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (292 aa)
ugpC_2Unannotated protein; Belongs to the ABC transporter superfamily. (371 aa)
yuaFUnannotated protein. (178 aa)
A21D_00025Unannotated protein. (245 aa)
rnrUnannotated protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (722 aa)
A21D_00251Unannotated protein; Belongs to the CvfB family. (288 aa)
metG_1Unannotated protein. (109 aa)
cspB_1Unannotated protein. (65 aa)
rhoUnannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (427 aa)
A21D_01023Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (462 aa)
infAUnannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpsQUnannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (87 aa)
rplBUnannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsLUnannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (137 aa)
Your Current Organism:
Virgibacillus dokdonensis
NCBI taxonomy Id: 302167
Other names: DSM 16826, KCTC 3933, Ornithinibacillus sp. NY-1, Ornithinibacillus sp. NY-11, Ornithinibacillus sp. NY-6, V. dokdonensis, Virgibacillus dokdonensis Yoon et al. 2005, strain DSW-10
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