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| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (515 aa) |
| | A0A4W2BNU5 | Reverse transcriptase domain-containing protein. (1128 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (345 aa) |
| | ZNF365 | Zinc finger protein 365. (405 aa) |
| | TERF2IP | TERF2 interacting protein. (399 aa) |
| | SPIRE1 | Spire type actin nucleation factor 1. (781 aa) |
| | INO80E | INO80 complex subunit E. (244 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa) |
| | HMGA2 | Uncharacterized protein. (109 aa) |
| | FOXM1 | Fork-head domain-containing protein. (760 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (212 aa) |
| | KMT5C | Lysine methyltransferase 5C. (438 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1941 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2040 aa) |
| | FAM168A | Family with sequence similarity 168 member A. (244 aa) |
| | EP400 | E1A binding protein p400. (3096 aa) |
| | PML | Promyelocytic leukemia. (871 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (700 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (513 aa) |
| | FBH1 | F-box DNA helicase 1. (1045 aa) |
| | PPP4R3B | Protein phosphatase 4 regulatory subunit 3B. (820 aa) |
| | RAD51AP1 | RAD51 associated protein 1. (366 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (149 aa) |
| | HDAC10 | Histone deacetylase 10. (671 aa) |
| | A0A4W2DZY8 | MOEP19 domain-containing protein. (598 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1966 aa) |
| | ACTB | Actin beta. (375 aa) |
| | MORF4L1 | Mortality factor 4 like 1. (362 aa) |
| | HSF1 | Heat shock transcription factor 1. (553 aa) |
| | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1997 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | A0A4W2DUQ2 | FH2 domain-containing protein. (248 aa) |
| | FMN2 | Formin 2. (1611 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (877 aa) |
| | SIRT1 | Sirtuin 1. (734 aa) |
| | CHEK1 | Checkpoint kinase 1. (677 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2563 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (832 aa) |
| | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (644 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (859 aa) |
| | WAS | WASP actin nucleation promoting factor. (559 aa) |
| | A0A4W2DN34 | KH type-2 domain-containing protein. (85 aa) |
| | SIRT6 | Sirtuin 6. (391 aa) |
| | USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa) |
| | TWIST1 | Twist family bHLH transcription factor 1. (201 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (513 aa) |
| | CYREN | Cell cycle regulator of NHEJ. (152 aa) |
| | A0A4W2D9V3 | Reverse transcriptase domain-containing protein. (738 aa) |
| | MAGEF1 | MAGE family member F1. (307 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (573 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (573 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1175 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) |
| | PARG | Poly(ADP-ribose) glycohydrolase. (946 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1544 aa) |
| | SHLD2 | Shieldin complex subunit 2. (962 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1016 aa) |
| | A0A4W2CX26 | Uncharacterized protein. (284 aa) |
| | A0A4W2CWA2 | Uncharacterized protein. (226 aa) |
| | INO80 | INO80 complex ATPase subunit. (1584 aa) |
| | A0A4W2CV54 | Reverse transcriptase domain-containing protein. (798 aa) |
| | A0A4W2CT96 | Reverse transcriptase domain-containing protein. (1169 aa) |
| | A0A4W2CSP1 | Uncharacterized protein. (319 aa) |
| | MRGBP | MRG domain binding protein. (204 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (731 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (552 aa) |
| | EPC1 | Enhancer of polycomb homolog. (842 aa) |
| | A0A4W2CLZ1 | Reverse transcriptase domain-containing protein. (704 aa) |
| | INO80D | INO80 complex subunit D. (1026 aa) |
| | A0A4W2CJK2 | Uncharacterized protein. (291 aa) |
| | AXIN2 | Axin 2. (836 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (831 aa) |
| | RNF169 | Ring finger protein 169. (708 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | A0A4W2CG09 | MAGE domain-containing protein. (153 aa) |
| | XRCC1 | X-ray repair cross complementing 1. (692 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4122 aa) |
| | TEX15 | Testis expressed 15, meiosis and synapsis associated. (2864 aa) |
| | A0A4W2CDR2 | Reverse transcriptase domain-containing protein. (738 aa) |
| | A0A4W2CCW8 | Reverse transcriptase domain-containing protein. (1148 aa) |
| | A0A4W2CBX4 | Uncharacterized protein. (152 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (540 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | DHX9 | DExH-box helicase 9. (1287 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | OTUB1 | Ubiquitin thioesterase. (291 aa) |
| | OOEP | Oocyte expressed protein. (140 aa) |
| | CCDC197 | Coiled-coil domain containing 197. (290 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (416 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (987 aa) |
| | YY1 | YY1 transcription factor. (415 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (449 aa) |
| | SLF2 | SMC5-SMC6 complex localization factor 2. (1167 aa) |
| | A0A4W2BZY5 | Reverse transcriptase domain-containing protein. (738 aa) |
| | A0A4W2BZA0 | Fork-head domain-containing protein. (697 aa) |
| | KMT5B | Lysine methyltransferase 5B. (911 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (307 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (638 aa) |
| | KLHL15 | Kelch like family member 15. (602 aa) |
| | DEK | DEK proto-oncogene. (375 aa) |
| | FUS | FUS RNA binding protein. (512 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | TFPT | TCF3 fusion partner. (251 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | PARPBP | PARP1 binding protein. (580 aa) |
| | RMI2 | RecQ mediated genome instability 2. (157 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (397 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (504 aa) |
| | HELB | DNA helicase B. (1136 aa) |
| | AUNIP | Aurora kinase A and ninein interacting protein. (357 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (328 aa) |
| | BABAM2 | BRISC and BRCA1 A complex member 2. (383 aa) |
| | TRIM28 | Tripartite motif containing 28. (838 aa) |
| | BCL7C | BAF chromatin remodeling complex subunit BCL7C. (244 aa) |
| | ARID2 | AT-rich interaction domain 2. (1834 aa) |
| | WDR48 | WD repeat domain 48. (677 aa) |
| | POT1 | Protection of telomeres 1. (785 aa) |
| | MCRS1 | Microspherule protein 1. (462 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (253 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1266 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa) |
| | TIMELESS | Timeless circadian regulator. (1213 aa) |
| | NPAS2 | Neuronal PAS domain protein 2. (849 aa) |
| | SPIRE2 | Spire type actin nucleation factor 2. (763 aa) |
| | TMEM161A | Transmembrane protein 161A. (478 aa) |
| | MBTD1 | Mbt domain containing 1. (692 aa) |
| | NUDT16L1 | Nudix hydrolase 16 like 1. (211 aa) |
| | EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1291 aa) |
| | CCDC117 | Coiled-coil domain containing 117. (278 aa) |
| | EPC2 | Enhancer of polycomb homolog. (832 aa) |
| | UBQLN4 | Ubiquilin 4. (734 aa) |
| | A0A4W2EZ53 | MRG domain-containing protein. (258 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2465 aa) |
| | A0A4W2EYF1 | Reverse transcriptase domain-containing protein. (738 aa) |
| | BABAM1 | BRISC and BRCA1 A complex member 1. (332 aa) |
| | BRD8 | Bromodomain containing 8. (1235 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1551 aa) |
| | PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (412 aa) |
| | FIGNL1 | Fidgetin like 1; Belongs to the AAA ATPase family. (677 aa) |
| | ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (421 aa) |
| | HELQ | Helicase, POLQ like. (1092 aa) |
| | UIMC1 | Ubiquitin interaction motif containing 1. (753 aa) |
| | A0A4W2ERQ5 | Reverse transcriptase domain-containing protein. (1152 aa) |
| | HDGFL2 | HDGF like 2. (673 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (739 aa) |
| | POLQ | DNA polymerase theta. (2585 aa) |
| | A0A4W2EMP6 | Uncharacterized protein. (232 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (550 aa) |
| | BCL7A | BAF chromatin remodeling complex subunit BCL7A. (231 aa) |
| | SIRT7 | Sirtuin 7. (420 aa) |
