STRINGSTRING
A0A4W2DC90 A0A4W2DC90 A0A4W2D7Q2 A0A4W2D7Q2 A0A4W2D5Z2 A0A4W2D5Z2 SMUG1 SMUG1 ERCC6 ERCC6 PARP2 PARP2 OGG1 OGG1 A0A4W2BS76 A0A4W2BS76 A0A4W2BUF7 A0A4W2BUF7 WRN WRN A0A4W2C0Y8 A0A4W2C0Y8 NEIL3 NEIL3 NEIL1 NEIL1 A0A4W2C7A9 A0A4W2C7A9 A0A4W2C8Q6 A0A4W2C8Q6 POLE POLE XRCC1 XRCC1 A0A4W2CHD7 A0A4W2CHD7 LIG1 LIG1 POLD1 POLD1 A0A4W2CNF0 A0A4W2CNF0 ACACB ACACB POLG POLG XPA XPA RPA1 RPA1 FEN1 FEN1 DNA2 DNA2 APEX1 APEX1 A0A4W2F465 A0A4W2F465 TDG TDG A0A4W2F279 A0A4W2F279 A0A4W2EZE9 A0A4W2EZE9 A0A4W2EWF7 A0A4W2EWF7 RPA3 RPA3 A0A4W2EPQ5 A0A4W2EPQ5 POLQ POLQ HMGA2 HMGA2 A0A4W2EEB8 A0A4W2EEB8 A0A4W2EBN3 A0A4W2EBN3 USP47 USP47 A0A4W2E4U3 A0A4W2E4U3 A0A4W2E4N5 A0A4W2E4N5 POLL POLL A0A4W2E1T5 A0A4W2E1T5 HUWE1 HUWE1 A0A4W2DZE6 A0A4W2DZE6 MUTYH MUTYH APEX2 APEX2 LIG3 LIG3 A0A4W2DSD6 A0A4W2DSD6 NTHL1 NTHL1 A0A4W2DG76 A0A4W2DG76 PCNA PCNA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2DC90Reverse transcriptase domain-containing protein. (732 aa)
A0A4W2D7Q2Reverse transcriptase domain-containing protein. (383 aa)
A0A4W2D5Z2Reverse transcriptase domain-containing protein. (794 aa)
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (295 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1544 aa)
PARP2Poly [ADP-ribose] polymerase. (577 aa)
OGG18-oxoguanine DNA glycosylase. (345 aa)
A0A4W2BS76Reverse transcriptase domain-containing protein. (788 aa)
A0A4W2BUF7DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (531 aa)
WRNWRN RecQ like helicase. (1409 aa)
A0A4W2C0Y8Reverse transcriptase domain-containing protein. (762 aa)
NEIL3Nei like DNA glycosylase 3. (620 aa)
NEIL1Nei like DNA glycosylase 1. (390 aa)
A0A4W2C7A9Reverse transcriptase domain-containing protein. (704 aa)
A0A4W2C8Q6Reverse transcriptase domain-containing protein. (338 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
XRCC1X-ray repair cross complementing 1. (692 aa)
A0A4W2CHD7Reverse transcriptase domain-containing protein. (689 aa)
LIG1DNA ligase. (1303 aa)
POLD1DNA polymerase. (1106 aa)
A0A4W2CNF0Reverse transcriptase domain-containing protein. (783 aa)
ACACBAcetyl-CoA carboxylase beta. (2455 aa)
POLGDNA polymerase gamma, catalytic subunit. (1217 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
DNA2DNA replication helicase/nuclease 2. (1061 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
A0A4W2F465Uncharacterized protein. (157 aa)
TDGThymine DNA glycosylase. (454 aa)
A0A4W2F279Uncharacterized protein. (242 aa)
A0A4W2EZE9Reverse transcriptase domain-containing protein. (789 aa)
A0A4W2EWF7Reverse transcriptase domain-containing protein. (683 aa)
RPA3Replication protein A3. (121 aa)
A0A4W2EPQ5Reverse transcriptase domain-containing protein. (253 aa)
POLQDNA polymerase theta. (2585 aa)
HMGA2Uncharacterized protein. (109 aa)
A0A4W2EEB8Reverse transcriptase domain-containing protein. (350 aa)
A0A4W2EBN3Reverse transcriptase domain-containing protein. (340 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1374 aa)
A0A4W2E4U3Reverse transcriptase domain-containing protein. (729 aa)
A0A4W2E4N5Uncharacterized protein. (213 aa)
POLLDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa)
A0A4W2E1T5Uncharacterized protein. (76 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4364 aa)
A0A4W2DZE6Reverse transcriptase domain-containing protein. (346 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (526 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (513 aa)
LIG3DNA ligase. (943 aa)
A0A4W2DSD6Uncharacterized protein. (513 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (313 aa)
A0A4W2DG76Reverse transcriptase domain-containing protein. (247 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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