STRINGSTRING
CENPF CENPF PPP1CC PPP1CC A0A4W2E0S0 A0A4W2E0S0 PPP2R5C PPP2R5C CDC20B CDC20B CKAP5 CKAP5 KNTC1 KNTC1 NUP98 NUP98 NUP107 NUP107 CENPT CENPT KNL1 KNL1 BUB1B BUB1B DSN1 DSN1 A0A4W2ENM2 A0A4W2ENM2 KIF2A KIF2A CENPP CENPP A0A4W2ET95 A0A4W2ET95 NUP133 NUP133 CLIP1 CLIP1 SGO1 SGO1 BIRC5 BIRC5 DYNC1H1 DYNC1H1 AURKB AURKB PLK1 PLK1 SEH1L SEH1L DYNLL2 DYNLL2 A0A4W2BU60 A0A4W2BU60 CENPA CENPA A0A4W2BWX2 A0A4W2BWX2 NDE1 NDE1 SKA1 SKA1 RANGAP1 RANGAP1 PPP2R5D PPP2R5D CENPU CENPU CENPM CENPM NUP85 NUP85 NDEL1 NDEL1 NSL1 NSL1 A0A4W2C9M0 A0A4W2C9M0 SEC13 SEC13 SGO2 SGO2 CENPH CENPH MIS12 MIS12 A0A4W2CBR1 A0A4W2CBR1 SPDL1 SPDL1 A0A4W2CC75 A0A4W2CC75 A0A4W2CCK1 A0A4W2CCK1 PPP2R1B PPP2R1B A0A4W2CET6 A0A4W2CET6 B9D2 B9D2 MEIOC MEIOC RANBP2 RANBP2 KIF18A KIF18A A0A4W2CH33 A0A4W2CH33 A0A4W2CHR1 A0A4W2CHR1 NUP160 NUP160 A0A4W2CUT9 A0A4W2CUT9 MAPRE1 MAPRE1 NUDC NUDC PPP2R1A PPP2R1A CENPO CENPO A0A4W2D165 A0A4W2D165 A0A4W2D1A4 A0A4W2D1A4 DYNC1I2 DYNC1I2 A0A4W2DAQ9 A0A4W2DAQ9 A0A4W2DBC1 A0A4W2DBC1 A0A4W2DCW1 A0A4W2DCW1 SPC25 SPC25 CDCA8 CDCA8 A0A4W2DG34 A0A4W2DG34 BUB1 BUB1 MAD2L1 MAD2L1 TAOK1 TAOK1 A0A4W2DNR2 A0A4W2DNR2 SPC24 SPC24 DYNC1LI1 DYNC1LI1 KIF2B KIF2B A0A4W2DQW9 A0A4W2DQW9 CLIP2 CLIP2 DYNC1I1 DYNC1I1 CLASP2 CLASP2 CENPC CENPC A0A4W2EWR2 A0A4W2EWR2 KIF2C KIF2C RCC2 RCC2 A0A4W2EZ08 A0A4W2EZ08 LOC113894698 LOC113894698 NUF2 NUF2 CENPE CENPE NUP37 NUP37 PPP2R5E PPP2R5E LOC113875854 LOC113875854 PAFAH1B1 PAFAH1B1 PPP2R5B PPP2R5B DYNC1LI2 DYNC1LI2 ITGB3BP ITGB3BP NUP43 NUP43 A0A4W2GK22 A0A4W2GK22 ZWINT ZWINT ZW10 ZW10 PPP2R5A PPP2R5A TAOK2 TAOK2 AURKC AURKC AHCTF1 AHCTF1 CDC20 CDC20 PPP2CB PPP2CB CENPL CENPL RPS27 RPS27 XPO1 XPO1 PPP2CA PPP2CA CLASP1 CLASP1 NDC80 NDC80 CENPK CENPK A0A4W2HUR1 A0A4W2HUR1 CENPS CENPS CENPQ CENPQ CENPN CENPN LOC113895027 LOC113895027 INCENP INCENP BUB3 BUB3 A0A4W2DVY5 A0A4W2DVY5 A0A4W2DXK0 A0A4W2DXK0 MAD1L1 MAD1L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CENPFCentromere protein F. (3259 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
A0A4W2E0S0Dynein light chain. (89 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa)
CDC20BCell division cycle 20B. (514 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
KNTC1Kinetochore associated 1. (2205 aa)
NUP98Nucleoporin 98. (1816 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (960 aa)
CENPTCentromere protein T. (563 aa)
KNL1Kinetochore scaffold 1. (1998 aa)
BUB1BUncharacterized protein. (1062 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (353 aa)
A0A4W2ENM2Uncharacterized protein. (270 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
CENPPCentromere protein P. (345 aa)
A0A4W2ET95Uncharacterized protein. (589 aa)
NUP133Nucleoporin 133. (1156 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
SGO1Shugoshin 1. (525 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4645 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
DYNLL2Dynein light chain. (128 aa)
A0A4W2BU60Uncharacterized protein. (82 aa)
CENPAHistone domain-containing protein. (138 aa)
A0A4W2BWX2Centromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. (178 aa)
NDE1NudE neurodevelopment protein 1. (352 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (303 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa)
CENPUCentromere protein U. (433 aa)
CENPMUncharacterized protein. (230 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (377 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
A0A4W2C9M0SKA2 domain-containing protein. (122 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa)
SGO2Shugoshin 2. (1338 aa)
CENPHCentromere protein H. (252 aa)
MIS12MIS12 kinetochore complex component. (206 aa)
A0A4W2CBR1Dynein light chain. (63 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (620 aa)
A0A4W2CC75SKA2 domain-containing protein. (121 aa)
A0A4W2CCK1Uncharacterized protein. (113 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (805 aa)
A0A4W2CET6Serine/threonine-protein phosphatase. (259 aa)
B9D2B9 domain containing 2. (175 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
RANBP2RAN binding protein 2. (3143 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (893 aa)
A0A4W2CH33Metallophos domain-containing protein. (127 aa)
A0A4W2CHR1Histone domain-containing protein. (127 aa)
NUP160Nucleoporin 160. (1402 aa)
A0A4W2CUT9Uncharacterized protein. (277 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (295 aa)
NUDCNuclear distribution C, dynein complex regulator. (332 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
CENPOCentromere protein O. (296 aa)
A0A4W2D165Histone domain-containing protein. (137 aa)
A0A4W2D1A4Dynein light chain. (89 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
A0A4W2DAQ9SKA2 domain-containing protein. (62 aa)
A0A4W2DBC1Dynein light chain. (87 aa)
A0A4W2DCW1Uncharacterized protein. (85 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
CDCA8Cell division cycle associated 8. (285 aa)
A0A4W2DG34Dynein light chain. (69 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa)
MAD2L1HORMA domain-containing protein. (215 aa)
TAOK1TAO kinase 1. (1001 aa)
A0A4W2DNR240S ribosomal protein S27. (96 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (223 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
A0A4W2DQW9Histone domain-containing protein. (126 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1047 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
CLASP2Uncharacterized protein. (1517 aa)
CENPCCentromere protein C. (945 aa)
A0A4W2EWR2Histone domain-containing protein. (110 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (724 aa)
RCC2Regulator of chromosome condensation 2. (520 aa)
A0A4W2EZ08Uncharacterized protein. (206 aa)
LOC11389469840S ribosomal protein S27. (84 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (462 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2586 aa)
NUP37Nucleoporin 37. (326 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa)
LOC113875854Protein kinase domain-containing protein. (258 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (628 aa)
ITGB3BPCentromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. (178 aa)
NUP43Nucleoporin 43. (380 aa)
A0A4W2GK22Dynein light chain. (84 aa)
ZWINTUncharacterized protein. (286 aa)
ZW10Zw10 kinetochore protein. (779 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (489 aa)
TAOK2TAO kinase 2. (1125 aa)
AURKCProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
AHCTF1AT-hook containing transcription factor 1. (2276 aa)
CDC20Cell division cycle 20. (499 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CENPLCentromere protein L. (346 aa)
RPS2740S ribosomal protein S27. (84 aa)
XPO1Exportin 1. (1071 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CLASP1Cytoplasmic linker associated protein 1. (1569 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
CENPKCentromere protein K. (271 aa)
A0A4W2HUR1HORMA domain-containing protein. (197 aa)
CENPSCentromere protein S. (139 aa)
CENPQCentromere protein Q. (269 aa)
CENPNUncharacterized protein. (339 aa)
LOC113895027Dynein light chain. (89 aa)
INCENPInner centromere protein. (877 aa)
BUB3BUB3 mitotic checkpoint protein. (343 aa)
A0A4W2DVY5Uncharacterized protein. (311 aa)
A0A4W2DXK0HORMA domain-containing protein. (258 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (768 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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