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| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | KNG1 | Kininogen 1. (621 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (445 aa) |
| | PLD1 | Phospholipase. (1126 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | A0A4W2EXY8 | Uncharacterized protein. (414 aa) |
| | RAC2 | Rac family small GTPase 2. (209 aa) |
| | S1PR5 | Sphingosine-1-phosphate receptor 5. (399 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa) |
| | GNAI2 | G protein subunit alpha i2. (436 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (747 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa) |
| | S1PR4 | Sphingosine-1-phosphate receptor 4. (385 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (425 aa) |
| | ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif 19. (1225 aa) |
| | SRMS | Tyrosine-protein kinase. (504 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (399 aa) |
| | GAB2 | GRB2 associated binding protein 2. (666 aa) |
| | A0A4W2BQE1 | Uncharacterized protein. (165 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | LOC113889031 | Uncharacterized protein. (146 aa) |
| | A0A4W2BU60 | Uncharacterized protein. (82 aa) |
| | BCL2 | BCL2 apoptosis regulator. (229 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (485 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (326 aa) |
| | RAC3 | Rac family small GTPase 3. (258 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CERS3 | Ceramide synthase 3. (387 aa) |
| | GNA12 | G protein subunit alpha 12. (382 aa) |
| | RAC1 | Rac family small GTPase 1. (257 aa) |
| | PLD2 | Phospholipase. (1088 aa) |
| | SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (549 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (805 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | A0A4W2CET6 | Serine/threonine-protein phosphatase. (259 aa) |
| | A0A4W2CH33 | Metallophos domain-containing protein. (127 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | NSMAF | Neutral sphingomyelinase activation associated factor. (920 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (603 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | A0A4W2CN33 | Neutral ceramidase. (786 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (634 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (614 aa) |
| | CERS5 | Ceramide synthase 5. (452 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (319 aa) |
| | SPHK2 | Sphingosine kinase 2. (661 aa) |
| | CERS4 | Ceramide synthase 4. (393 aa) |
| | TMIGD3 | Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | MAP2K1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (484 aa) |
| | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (473 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (428 aa) |
| | A0A4W2DB09 | Abhydrolase_3 domain-containing protein. (199 aa) |
| | A0A4W2DB19 | Abhydrolase_3 domain-containing protein. (204 aa) |
| | FCER1A | Fc fragment of IgE receptor Ia. (260 aa) |
| | A0A4W2DFZ3 | Uncharacterized protein. (306 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (747 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (617 aa) |
| | IFITM10 | Interferon induced transmembrane protein 10. (130 aa) |
| | GNAI1 | G protein subunit alpha i1. (417 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ERAS | ES cell expressed Ras. (185 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1544 aa) |
| | A0A4W2DS38 | Uncharacterized protein. (409 aa) |
| | CERS2 | Ceramide synthase 2. (386 aa) |
| | CERS6 | Ceramide synthase 6. (392 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (455 aa) |
| | A0A4W2DVL1 | Uncharacterized protein. (146 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa) |
| | SPHK1 | Sphingosine kinase 1. (489 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (471 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | LOC113886588 | Uncharacterized protein. (101 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1218 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (564 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa) |
| | MS4A2 | Membrane spanning 4-domains A2. (243 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa) |
| | ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif 17. (1120 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | PTK6 | Tyrosine-protein kinase. (450 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | SGMS1 | Sphingomyelin synthase 1. (413 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | SGMS2 | Sphingomyelin synthase 2. (365 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (489 aa) |
| | A0A4W2GYG4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | PPP2R3B | EF-hand domain-containing protein. (611 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (552 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (974 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa) |
