(91 nodes) Mixed, incl. Microbody membrane, and Claudin network (Otolemur garnettii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PEX11B	Peroxisomal biogenesis factor 11 beta. (259 aa)
	PEX7	Peroxisomal biogenesis factor 7. (262 aa)
	LONP2	Lon protease homolog; Belongs to the peptidase S16 family. (818 aa)
	CHAT	Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (639 aa)
	JAM2	Junctional adhesion molecule 2. (279 aa)
	TBC1D15	TBC1 domain family member 15. (691 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (362 aa)
	PEX11G	Peroxisomal biogenesis factor 11 gamma. (241 aa)
	LMBRD1	LMBR1 domain containing 1. (542 aa)
	CLDN16	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (243 aa)
	EPHX2	Epoxide hydrolase 2. (555 aa)
	CLDN17	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	SLC25A36	Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	SCP2D1	SCP2 sterol binding domain containing 1. (156 aa)
	CGN	Myosin_tail_1 domain-containing protein. (1197 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1741 aa)
	TBC1D17	TBC1 domain family member 17. (618 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	H0WTR7_OTOGA	Uncharacterized protein. (242 aa)
	CLDN34	Uncharacterized protein. (216 aa)
	MARVELD2	MARVEL domain containing 2. (558 aa)
	PXMP2	Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)
	GDAP1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
	SLC25A33	Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
	MPV17	Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
	GDAP1L1	Uncharacterized protein. (367 aa)
	PHYH	Phytanoyl-CoA 2-hydroxylase. (343 aa)
	NMT2	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (529 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	CLDN6	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	CRAT	Carnitine acetyltransferase isoform 1 (Predicted); Belongs to the carnitine/choline acetyltransferase family. (626 aa)
	ACBD4	Acyl-CoA binding domain containing 4. (301 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (622 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (202 aa)
	PXMP4	Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
	PEX5	Peroxisomal biogenesis factor 5. (661 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1216 aa)
	PEX14	Peroxisomal biogenesis factor 14. (376 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (364 aa)
	PEX16	Peroxisomal membrane protein PEX16. (338 aa)
	PEX6	Peroxisomal biogenesis factor 6. (980 aa)
	CLDN2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
	NMT1	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (562 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	ABCD4	ATP binding cassette subfamily D member 4. (606 aa)
	OCLN	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (595 aa)
	CROT	Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
	H0XAE3_OTOGA	DUF4515 domain-containing protein. (277 aa)
	CLDN18	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (249 aa)
	PEX3	Uncharacterized protein. (373 aa)
	H0XBW6_OTOGA	Uncharacterized protein; Belongs to the MAGUK family. (1221 aa)
	VSIG2	V-set and immunoglobulin domain containing 2. (327 aa)
	ESAM	Endothelial cell adhesion molecule. (391 aa)
	ACBD5	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters. (524 aa)
	ACBD6	Acyl-CoA binding domain containing 6. (282 aa)
	SLC25A17	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	TJP3	Tight junction protein 3; Belongs to the MAGUK family. (921 aa)
	CLDN19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	CLDN20	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	H0XIC1_OTOGA	EF-hand domain-containing protein. (599 aa)
	CLDN25	Claudin 25. (207 aa)
	FAM185A	Family with sequence similarity 185 member A. (299 aa)
	F11R	F11 receptor. (277 aa)
	H0XL55_OTOGA	Uncharacterized protein. (373 aa)
	PEX26	Peroxisomal biogenesis factor 26. (362 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (693 aa)
	LOC111728525	ACB domain-containing protein. (87 aa)
	PEX11A	Peroxisomal biogenesis factor 11 alpha. (230 aa)
	LOC100960865	MaoC-like domain-containing protein. (168 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	CLDN23	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (286 aa)
	JAM3	Junctional adhesion molecule 3. (308 aa)
	CLDN9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
	CLDN8	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
	CLDN11	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
	TYSND1	Trypsin domain containing 1. (566 aa)
	LOC100958119	MaoC-like domain-containing protein. (168 aa)
	CLDN14	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (741 aa)
	CLDN7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
	MPV17L	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (746 aa)
	PEX13	Peroxisomal biogenesis factor 13. (407 aa)
	PEX19	Uncharacterized protein. (300 aa)
	PEX10	Peroxisomal biogenesis factor 10. (326 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD2	ENSOGAP00000021438	ENSOGAP00000021042	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 2.	0.907
ABCD1	ABCD3	ENSOGAP00000021438	ENSOGAP00000008572	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.944
ABCD1	ABCD4	ENSOGAP00000021438	ENSOGAP00000012151	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 4.	0.898
ABCD1	ACAA1	ENSOGAP00000021438	ENSOGAP00000005561	ATP binding cassette subfamily D member 1.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.447
ABCD1	ACBD4	ENSOGAP00000021438	ENSOGAP00000008337	ATP binding cassette subfamily D member 1.	Acyl-CoA binding domain containing 4.	0.622
ABCD1	ACBD5	ENSOGAP00000021438	ENSOGAP00000014220	ATP binding cassette subfamily D member 1.	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	0.622
ABCD1	ACBD6	ENSOGAP00000021438	ENSOGAP00000014384	ATP binding cassette subfamily D member 1.	Acyl-CoA binding domain containing 6.	0.604
ABCD1	AGPS	ENSOGAP00000021438	ENSOGAP00000011813	ATP binding cassette subfamily D member 1.	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	0.512
ABCD1	CLDN1	ENSOGAP00000021438	ENSOGAP00000007568	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN14	ENSOGAP00000021438	ENSOGAP00000020627	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN17	ENSOGAP00000021438	ENSOGAP00000003238	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN18	ENSOGAP00000021438	ENSOGAP00000012872	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN19	ENSOGAP00000021438	ENSOGAP00000015532	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN2	ENSOGAP00000021438	ENSOGAP00000011566	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN20	ENSOGAP00000021438	ENSOGAP00000015631	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN3	ENSOGAP00000021438	ENSOGAP00000015632	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN4	ENSOGAP00000021438	ENSOGAP00000009250	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN5	ENSOGAP00000021438	ENSOGAP00000021092	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN6	ENSOGAP00000021438	ENSOGAP00000007689	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441
ABCD1	CLDN7	ENSOGAP00000021438	ENSOGAP00000021058	ATP binding cassette subfamily D member 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.441