STRINGSTRING
MCM5 MCM5 ORC6 ORC6 MCM4 MCM4 CDT1 CDT1 ORC5 ORC5 CDC6 CDC6 MCM2 MCM2 ORC4 ORC4 MCM7 MCM7 MCM10 MCM10 ORC2 ORC2 MCM6 MCM6 ORC3 ORC3 CDC45 CDC45 MCM3 MCM3 ORC1 ORC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM5DNA helicase; Belongs to the MCM family. (721 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
MCM4DNA helicase; Belongs to the MCM family. (739 aa)
CDT1DNA replication factor Cdt1. (530 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
MCM10Protein MCM10 homolog. (873 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
ORC3Origin recognition complex subunit 3 isoform X1. (714 aa)
CDC45Cell division control protein 45 homolog. (567 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (852 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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