STRINGSTRING
EDM25778.1 EDM25778.1 EDM25780.1 EDM25780.1 EDM25787.1 EDM25787.1 EDM25797.1 EDM25797.1 EDM24826.1 EDM24826.1 EDM24700.1 EDM24700.1 EDM27126.1 EDM27126.1 rph-2 rph-2 EDM27170.1 EDM27170.1 EDM27187.1 EDM27187.1 EDM27234.1 EDM27234.1 EDM26125.1 EDM26125.1 EDM25466.1 EDM25466.1 EDM26128.1 EDM26128.1 EDM26131.1 EDM26131.1 EDM26138.1 EDM26138.1 EDM26140.1 EDM26140.1 EDM29437.1 EDM29437.1 EDM29469.1 EDM29469.1 EDM29513.1 EDM29513.1 EDM29547.1 EDM29547.1 EDM29606.1 EDM29606.1 uvrB uvrB EDM26728.1 EDM26728.1 orn orn EDM24728.1 EDM24728.1 EDM24729.1 EDM24729.1 EDM29257.1 EDM29257.1 EDM29384.1 EDM29384.1 rnz rnz ybeY ybeY rnc rnc EDM25244.1 EDM25244.1 EDM25258.1 EDM25258.1 EDM25247.1 EDM25247.1 EDM27770.1 EDM27770.1 rnpA rnpA EDM27794.1 EDM27794.1 EDM27803.1 EDM27803.1 EDM27820.1 EDM27820.1 EDM27864.1 EDM27864.1 EDM25853.1 EDM25853.1 EDM25035.1 EDM25035.1 EDM26613.1 EDM26613.1 EDM24686.1 EDM24686.1 EDM25088.1 EDM25088.1 EDM25105.1 EDM25105.1 EDM25128.1 EDM25128.1 EDM24949.1 EDM24949.1 EDM24964.1 EDM24964.1 EDM25327.1 EDM25327.1 EDM24790.1 EDM24790.1 EDM24894.1 EDM24894.1 xseA xseA xseB xseB vapC vapC EDM26900.1 EDM26900.1 EDM26901.1 EDM26901.1 EDM28627.1 EDM28627.1 EDM28733.1 EDM28733.1 EDM28734.1 EDM28734.1 EDM28738.1 EDM28738.1 EDM28739.1 EDM28739.1 EDM28746.1 EDM28746.1 EDM28755.1 EDM28755.1 EDM28756.1 EDM28756.1 EDM28757.1 EDM28757.1 EDM28784.1 EDM28784.1 EDM28269.1 EDM28269.1 EDM28291.1 EDM28291.1 EDM28332.1 EDM28332.1 EDM28339.1 EDM28339.1 vapC-2 vapC-2 EDM28540.1 EDM28540.1 mutS2 mutS2 EDM25732.1 EDM25732.1 rnhB rnhB rnhA rnhA EDM29014.1 EDM29014.1 rny rny EDM29116.1 EDM29116.1 EDM25750.1 EDM25750.1 EDM25769.1 EDM25769.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDM25778.1Putative exonuclease; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (165 aa)
EDM25780.1COG1864 DNA/RNA endonuclease G, NUC1. (333 aa)
EDM25787.1COG1864 DNA/RNA endonuclease G, NUC1. (330 aa)
EDM25797.1Hypothetical protein. (289 aa)
EDM24826.1PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain. (126 aa)
EDM24700.1Endonuclease; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. (127 aa)
EDM27126.1Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (486 aa)
rph-2Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
EDM27170.1COG0587 DNA polymerase III, alpha subunit. (1223 aa)
EDM27187.1Hypothetical protein. (171 aa)
EDM27234.1Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. (182 aa)
EDM26125.1Restriction endonuclease-like protein. (105 aa)
EDM25466.1Type I restriction-modification enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1083 aa)
EDM26128.1Hypothetical protein; COG1637 Predicted nuclease of the RecB family. (272 aa)
EDM26131.1Hypothetical protein. (316 aa)
EDM26138.1DNA polymerase III, beta chain; COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). (465 aa)
EDM26140.1Hypothetical protein. (277 aa)
EDM29437.1Sialic acid-specific 9-O-acetylesterase. (522 aa)
EDM29469.1Sialic acid-specific 9-O-acetylesterase; COG2706 3-carboxymuconate cyclase. (737 aa)
EDM29513.1PHP-like protein; COG0613 Predicted metal-dependent phosphoesterases (PHP family). (282 aa)
EDM29547.1Hypothetical protein. (286 aa)
EDM29606.1Hypothetical cytosolic protein. (76 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (672 aa)
EDM26728.1TatD protein; COG0084 Mg-dependent DNase. (252 aa)
ornOligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (184 aa)
EDM24728.1COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). (209 aa)
EDM24729.1COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). (153 aa)
EDM29257.1Hypothetical protein. (353 aa)
EDM29384.1Hypothetical protein; COG0084 Mg-dependent DNase. (239 aa)
rnzMetal-dependent Hydrolase of the beta-lactamase superfamily III; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (352 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (160 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (232 aa)
EDM25244.1single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease. (572 aa)
EDM25258.1Hypothetical protein; COG5611 Predicted nucleic-acid-binding protein, contains PIN domain. (132 aa)
EDM25247.1COG1403 Restriction endonuclease. (105 aa)
EDM27770.1COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (210 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (131 aa)
EDM27794.1Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (151 aa)
EDM27803.1Glycosyl transferase, group 1:PHP-like protein; COG0176 Transaldolase. (714 aa)
EDM27820.1Hypothetical protein. (621 aa)
EDM27864.1PIN domain protein. (137 aa)
EDM25853.1DNA polymerase II; COG1193 Mismatch repair ATPase (MutS family). (148 aa)
EDM25035.1Hypothetical protein; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (177 aa)
EDM26613.1Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (939 aa)
EDM24686.1PIN domain protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain. (127 aa)
EDM25088.1COG0557 Exoribonuclease R; Belongs to the RNR ribonuclease family. (754 aa)
EDM25105.1Exodeoxyribonuclease (ExoA); COG0708 Exonuclease III. (258 aa)
EDM25128.1Type V secretory pathway protein; COG0084 Mg-dependent DNase. (260 aa)
EDM24949.1COG3744 Uncharacterized protein conserved in bacteria. (130 aa)
EDM24964.1Plasmid stabilization system; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system. (87 aa)
EDM25327.1COG1525 Micrococcal nuclease (thermonuclease) homologs. (158 aa)
EDM24790.1COG1530 Ribonucleases G and E. (534 aa)
EDM24894.1Hypothetical protein; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system. (87 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (443 aa)
xseBHypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (72 aa)
vapCVirulence associated protein C; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (133 aa)
EDM26900.1Exodeoxyribonuclease V, 135 kDa subunit; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1198 aa)
EDM26901.1COG1330 Exonuclease V gamma subunit. (1099 aa)
EDM28627.1COG4115 Uncharacterized protein conserved in bacteria. (87 aa)
EDM28733.1Hypothetical protein; COG3525 N-acetyl-beta-hexosaminidase. (1551 aa)
EDM28734.1Hypothetical protein. (1338 aa)
EDM28738.1Hypothetical protein. (837 aa)
EDM28739.1Hypothetical protein. (855 aa)
EDM28746.1Putative alpha-1,2-mannosidase. (1569 aa)
EDM28755.1Hypothetical protein. (868 aa)
EDM28756.1Hypothetical protein. (1499 aa)
EDM28757.1Short chain dehydrogenase; COG3291 FOG: PKD repeat. (1422 aa)
EDM28784.1Addiction module toxin, Txe/YoeB; COG4115 Uncharacterized protein conserved in bacteria. (87 aa)
EDM28269.1Hypothetical protein. (158 aa)
EDM28291.1Putative type I restriction enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1053 aa)
EDM28332.1Exonuclease; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (261 aa)
EDM28339.1Exoribonuclease, VacB/RNB family protein; COG0557 Exoribonuclease R. (668 aa)
vapC-2PilT protein-like protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (129 aa)
EDM28540.1COG4115 Uncharacterized protein conserved in bacteria. (84 aa)
mutS2MutS 2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (791 aa)
EDM25732.1Hypothetical protein. (88 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (209 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. (155 aa)
EDM29014.1Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (290 aa)
rnyHypothetical protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (507 aa)
EDM29116.1Hypothetical protein; COG0349 Ribonuclease D. (372 aa)
EDM25750.1COG0210 Superfamily I DNA and RNA helicases. (697 aa)
EDM25769.1Hypothetical protein; COG1864 DNA/RNA endonuclease G, NUC1. (291 aa)
Your Current Organism:
Lentisphaera araneosa
NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155
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