STRINGSTRING
IO99_01520 IO99_01520 scpB scpB IO99_02235 IO99_02235 IO99_02245 IO99_02245 IO99_02975 IO99_02975 moaC moaC moaA moaA IO99_02990 IO99_02990 IO99_05490 IO99_05490 IO99_07835 IO99_07835 IO99_08145 IO99_08145 IO99_08690 IO99_08690 IO99_11195 IO99_11195 iscS iscS IO99_11205 IO99_11205 mnmA mnmA IO99_11215 IO99_11215 IO99_12740 IO99_12740 IO99_12745 IO99_12745 IO99_14530 IO99_14530 IO99_16650 IO99_16650 IO99_17110 IO99_17110 prfA prfA thiI thiI IO99_17445 IO99_17445 IO99_17675 IO99_17675
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IO99_01520Ferrous iron transporter A; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
scpBSegregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (193 aa)
IO99_02235SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (68 aa)
IO99_02245Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
IO99_02975Molybdenum cofactor sulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa)
moaAHypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (336 aa)
IO99_02990Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
IO99_05490Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
IO99_07835SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (201 aa)
IO99_08145Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (77 aa)
IO99_08690Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
IO99_11195Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (402 aa)
IO99_11205Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
mnmAThiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
IO99_11215Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
IO99_12740Thiamine biosynthesis protein ThiF; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
IO99_12745Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
IO99_14530Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (830 aa)
IO99_16650MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
IO99_17110Queuosine synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (358 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa)
IO99_17445Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
IO99_17675Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.