STRINGSTRING
sat sat Ppha_0002 Ppha_0002 Ppha_0006 Ppha_0006 nadD nadD Ppha_2761 Ppha_2761 rpoB rpoB rpoC rpoC Ppha_2602 Ppha_2602 Ppha_2577 Ppha_2577 cas1-2 cas1-2 kdsB kdsB Ppha_2342 Ppha_2342 Ppha_2300 Ppha_2300 Ppha_2289 Ppha_2289 Ppha_2227 Ppha_2227 Ppha_2189 Ppha_2189 Ppha_2112 Ppha_2112 Ppha_2093 Ppha_2093 Ppha_1660 Ppha_1660 dnaX dnaX Ppha_1621 Ppha_1621 ispD ispD Ppha_1547 Ppha_1547 Ppha_1494 Ppha_1494 Ppha_1484 Ppha_1484 Ppha_1386 Ppha_1386 Ppha_1369 Ppha_1369 Ppha_1331 Ppha_1331 Ppha_1293 Ppha_1293 Ppha_1247 Ppha_1247 Ppha_1245 Ppha_1245 Ppha_1213 Ppha_1213 Ppha_1207 Ppha_1207 coaD coaD Ppha_1076 Ppha_1076 Ppha_1016 Ppha_1016 Ppha_0963 Ppha_0963 dnaG dnaG Ppha_0715 Ppha_0715 pnp pnp polA polA Ppha_0534 Ppha_0534 Ppha_0529 Ppha_0529 Ppha_0499 Ppha_0499 Ppha_0416 Ppha_0416 Ppha_0407 Ppha_0407 Ppha_0405 Ppha_0405 Ppha_0403 Ppha_0403 Ppha_0391 Ppha_0391 Ppha_0319 Ppha_0319 rpoA rpoA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
satKEGG: cch:Cag_1587 ATP-sulfurylase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; Belongs to the sulfate adenylyltransferase family. (403 aa)
Ppha_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
Ppha_0006PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: cph:Cpha266_0027 DNA polymerase B region. (811 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
Ppha_2761PFAM: Nucleotidyl transferase; KEGG: cch:Cag_0193 mannose-1-phosphate guanylyltransferase, putative. (320 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1303 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1497 aa)
Ppha_2602rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (170 aa)
Ppha_2577TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: pvi:Cvib_0325 DNA polymerase III, delta subunit. (346 aa)
cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (727 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
Ppha_2342KEGG: cch:Cag_1695 reverse transcriptase family protein. (344 aa)
Ppha_2300Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
Ppha_2289KEGG: cch:Cag_0518 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (471 aa)
Ppha_2227PFAM: RES domain protein; KEGG: neu:NE0821 hypothetical protein. (237 aa)
Ppha_2189PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: cph:Cpha266_0459 hypothetical protein. (343 aa)
Ppha_2112PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: pvi:Cvib_0153 RNA-directed DNA polymerase. (413 aa)
Ppha_2093PFAM: Nucleotidyl transferase; KEGG: plt:Plut_0673 glucose-1-phosphate thymidylyltransferase. (325 aa)
Ppha_1660TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family; PFAM: CRISPR-associated protein TM1801; KEGG: cph:Cpha266_1433 CRISPR-associated protein, Csd2 family. (346 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (401 aa)
Ppha_1621KEGG: cch:Cag_0933 DNA polymerase III, gamma/tau subunit. (171 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (243 aa)
Ppha_1547KEGG: cph:Cpha266_1195 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1189 aa)
Ppha_1494TIGRFAM: rfaE bifunctional protein; PFAM: PfkB domain protein; KEGG: pvi:Cvib_0937 RfaE bifunctional protein. (328 aa)
Ppha_1484PFAM: acylneuraminate cytidylyltransferase; KEGG: cph:Cpha266_1514 acylneuraminate cytidylyltransferase. (237 aa)
Ppha_1386TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pvi:Cvib_0875 diguanylate cyclase. (433 aa)
Ppha_1369DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: cph:Cpha266_1031 DNA-directed DNA polymerase. (426 aa)
Ppha_1331Molybdopterin-guanine dinucleotide biosynthesis protein B; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (364 aa)
Ppha_1293Adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; KEGG: cch:Cag_0846 cobalamin biosynthesis protein CobP. (178 aa)
Ppha_1247PFAM: filamentation induced by cAMP protein Fic; KEGG: hsm:HSM_1618 filamentation induced by cAMP protein Fic. (293 aa)
Ppha_1245PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: pvi:Cvib_0153 RNA-directed DNA polymerase. (413 aa)
Ppha_1213PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: cch:Cag_0722 HDIG; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (479 aa)
Ppha_1207TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: cch:Cag_0781 sigma-54 factor. (482 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
Ppha_1076PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: pvi:Cvib_0153 RNA-directed DNA polymerase. (413 aa)
Ppha_1016KEGG: cph:Cpha266_1828 nucleoside-diphosphate-sugar pyrophosphorylase. (458 aa)
Ppha_0963PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: pvi:Cvib_0153 RNA-directed DNA polymerase. (413 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (631 aa)
Ppha_0715KEGG: cph:Cpha266_0587 DNA-directed DNA polymerase. (389 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (728 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (944 aa)
Ppha_0534PFAM: acylneuraminate cytidylyltransferase; KEGG: dvl:Dvul_2588 N-acylneuraminate cytidylyltransferase. (234 aa)
Ppha_0529Nucleotidyl transferase; PFAM: CBS domain containing protein; Nucleotidyl transferase; KEGG: tdn:Tmden_0598 nucleotidyl transferase. (352 aa)
Ppha_0499Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (317 aa)
Ppha_0416PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: pvi:Cvib_0153 RNA-directed DNA polymerase. (413 aa)
Ppha_0407Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: pvi:Cvib_1552 UDP-N-acetylglucosamine pyrophosphorylase. (252 aa)
Ppha_0405KEGG: plt:Plut_1772 hypothetical protein. (117 aa)
Ppha_0403PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cch:Cag_1457 hypothetical protein. (295 aa)
Ppha_0391PFAM: phosphatidate cytidylyltransferase; KEGG: cch:Cag_1470 phosphatidate cytidylyltransferase; Belongs to the CDS family. (273 aa)
Ppha_0319PFAM: Nucleotidyl transferase; KEGG: cch:Cag_1821 mannose-1-phosphate guanylyltransferase, putative. (373 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (327 aa)
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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