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gcvPB gcvPB Ppha_0335 Ppha_0335 sucD sucD Ppha_0629 Ppha_0629 Ppha_0651 Ppha_0651 acsA acsA Ppha_0683 Ppha_0683 Ppha_0695 Ppha_0695 gcvH gcvH gcvPA gcvPA Ppha_0717 Ppha_0717 glyA glyA sucC sucC gpmA gpmA Ppha_0851 Ppha_0851 Ppha_0921 Ppha_0921 Ppha_0929 Ppha_0929 Ppha_0941 Ppha_0941 Ppha_1005 Ppha_1005 Ppha_1012 Ppha_1012 mdh mdh Ppha_1089 Ppha_1089 Ppha_1091 Ppha_1091 Ppha_1167 Ppha_1167 Ppha_1168 Ppha_1168 Ppha_1169 Ppha_1169 Ppha_1170 Ppha_1170 Ppha_1173 Ppha_1173 Ppha_1190 Ppha_1190 folD folD Ppha_1305 Ppha_1305 Ppha_1306 Ppha_1306 Ppha_1307 Ppha_1307 Ppha_1359 Ppha_1359 Ppha_1362 Ppha_1362 Ppha_1392 Ppha_1392 Ppha_1393 Ppha_1393 pfkA pfkA pgi pgi Ppha_1520 Ppha_1520 Ppha_1568 Ppha_1568 Ppha_1569 Ppha_1569 prs prs Ppha_1647 Ppha_1647 tpiA tpiA Ppha_1797 Ppha_1797 ackA ackA Ppha_2000 Ppha_2000 Ppha_2010 Ppha_2010 Ppha_2011 Ppha_2011 Ppha_2012 Ppha_2012 fbp fbp Ppha_2213 Ppha_2213 Ppha_2304 Ppha_2304 Ppha_2333 Ppha_2333 Ppha_2334 Ppha_2334 gcvT gcvT accD accD Ppha_2417 Ppha_2417 pgl pgl zwf zwf Ppha_2484 Ppha_2484 Ppha_2664 Ppha_2664 Ppha_2670 Ppha_2670 Ppha_2671 Ppha_2671 accA accA Ppha_2676 Ppha_2676 Ppha_2677 Ppha_2677 eno eno Ppha_2715 Ppha_2715 Ppha_2716 Ppha_2716 Ppha_2717 Ppha_2717 Ppha_2851 Ppha_2851 Ppha_2852 Ppha_2852 Ppha_2853 Ppha_2853 tal tal pgk pgk
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gcvPBGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (482 aa)
Ppha_0335PFAM: ROK family protein; KEGG: pvi:Cvib_0291 ROK family protein. (327 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (299 aa)
Ppha_0629KEGG: cph:Cpha266_0518 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (916 aa)
Ppha_0651PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: cch:Cag_0175 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (667 aa)
Ppha_0683Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (922 aa)
Ppha_0695PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1178 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (446 aa)
Ppha_0717PFAM: phosphofructokinase; KEGG: cch:Cag_1780 phosphofructokinase. (401 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
Ppha_0851TIGRFAM: aconitate hydratase 2; PFAM: aconitate hydratase domain protein; Aconitase B, N-terminal; KEGG: cph:Cpha266_0803 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (856 aa)
Ppha_0921TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: plt:Plut_1551 cysteine synthase K/M/A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa)
Ppha_0929KEGG: cte:CT0604 O-acetylhomoserine (thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (430 aa)
Ppha_0941KEGG: cph:Cpha266_1806 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. (272 aa)
Ppha_1005KEGG: cph:Cpha266_1817 serine O-acetyltransferase. (163 aa)
Ppha_1012PFAM: transferase hexapeptide repeat containing protein; KEGG: cph:Cpha266_1824 serine O-acetyltransferase. (174 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa)
Ppha_1089Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: cph:Cpha266_1271 malate dehydrogenase (oxaloacetate-decarboxylating). (409 aa)
Ppha_1091KEGG: cch:Cag_1420 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
Ppha_1167methylmalonyl-CoA mutase, large subunit; KEGG: cph:Cpha266_1164 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (712 aa)
Ppha_1168PFAM: methylmalonyl-CoA mutase; KEGG: cph:Cpha266_1165 methylmalonyl-CoA mutase. (591 aa)
Ppha_1169KEGG: cph:Cpha266_1166 acetyl-CoA carboxylase alpha subunit-like. (600 aa)
Ppha_1170TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cph:Cpha266_1167 methylmalonyl-CoA epimerase. (135 aa)
Ppha_1173PFAM: Transketolase central region; Transketolase domain protein; KEGG: cch:Cag_1192 transketolase-like. (327 aa)
Ppha_1190PFAM: Transketolase domain protein; KEGG: cph:Cpha266_1017 transketolase subunit A. (303 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa)
Ppha_1305PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: cph:Cpha266_1259 methyl-viologen-reducing hydrogenase, delta subunit. (149 aa)
Ppha_1306PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1260 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (656 aa)
Ppha_1307CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cch:Cag_1028 heterodisulfide reductase, subunit C/succinate dehydrogenase, subunit C. (497 aa)
Ppha_1359KEGG: cch:Cag_0901 ribose/galactose isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (144 aa)
Ppha_1362Fructose-1,6-bisphosphate aldolase, class II; KEGG: cph:Cpha266_1329 fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. (324 aa)
Ppha_1392PFAM: ATP-grasp domain protein; KEGG: cph:Cpha266_1307 ATP citrate lyase subunit 1. (398 aa)
Ppha_1393PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: cph:Cpha266_1306 ATP citrate lyase subunit 2. (610 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: cph:Cpha266_1095 glucose-6-phosphate isomerase; Belongs to the GPI family. (562 aa)
Ppha_1520TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: cph:Cpha266_1089 D-3-phosphoglycerate dehydrogenase. (526 aa)
Ppha_1568Oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cch:Cag_0859 oxaloacetate decarboxylase, alpha subunit. (641 aa)
Ppha_1569Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (510 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
Ppha_1647KEGG: cch:Cag_1108 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (289 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
Ppha_1797TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cph:Cpha266_1632 dihydrolipoamide dehydrogenase. (474 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
Ppha_2000TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: plt:Plut_1551 cysteine synthase K/M/A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa)
Ppha_2010KEGG: reh:H16_A2325 2-oxoglutarate dehydrogenase (E1); TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. (942 aa)
Ppha_20112-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (425 aa)
Ppha_2012TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rso:RSc1271 dihydrolipoamide dehydrogenase. (478 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: cph:Cpha266_0686 fructose-1,6-bisphosphatase. (333 aa)
Ppha_2213KEGG: cph:Cpha266_0680 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (741 aa)
Ppha_2304Succinate CoA transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. (503 aa)
Ppha_2333PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_2000 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (274 aa)
Ppha_2334PFAM: ribulose bisphosphate carboxylase large chain; KEGG: plt:Plut_0412 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family. (433 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (279 aa)
Ppha_2417KEGG: cph:Cpha266_2083 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (447 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (303 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (478 aa)
Ppha_2484TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: plt:Plut_0306 6-phosphogluconate dehydrogenase-like protein. (299 aa)
Ppha_2664KEGG: cph:Cpha266_0250 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. (405 aa)
Ppha_2670PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0241 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (628 aa)
Ppha_2671PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cph:Cpha266_0240 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (343 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (335 aa)
Ppha_2676acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
Ppha_2677acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (437 aa)
Ppha_2715CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cch:Cag_0129 succinate/fumarate oxidoreductase, putative. (282 aa)
Ppha_2716KEGG: cch:Cag_0128 succinate dehydrogenase/fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (344 aa)
Ppha_2717KEGG: cch:Cag_0127 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (567 aa)
Ppha_2851PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: plt:Plut_2080 succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (257 aa)
Ppha_2852KEGG: plt:Plut_2081 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (646 aa)
Ppha_2853TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: cph:Cpha266_0102 succinate dehydrogenase subunit C. (220 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (222 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: cch:Cag_0044 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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