STRINGSTRING
priA priA mtgA mtgA OSI08581.1 OSI08581.1 pilO pilO OSI08583.1 OSI08583.1 mrcA mrcA engB engB ccsB ccsB OSI08588.1 OSI08588.1 yafQ yafQ dipZ_1 dipZ_1 prsA1 prsA1 lptD lptD OSI08799.1 OSI08799.1 mviN mviN OSI08846.1 OSI08846.1 pbpG pbpG OSI08866.1 OSI08866.1 erpA erpA smc smc OSI08974.1 OSI08974.1 yceG yceG pqiB pqiB typA typA hscA_2 hscA_2 iscX iscX recB recB OSI08228.1 OSI08228.1 murB murB narJ narJ prfC prfC mlaC_1 mlaC_1 mrdB mrdB penA_1 penA_1 iscS iscS nifU nifU OSI08362.1 OSI08362.1 iscA iscA mpl mpl hupB hupB frdC frdC ruvB ruvB gyrA gyrA hscB hscB pilT_2 pilT_2 dinG dinG murA murA mltA mltA stoA stoA ylxH ylxH uvrD uvrD penA_2 penA_2 murE murE murF murF mraY mraY murD murD ftsW ftsW murG murG murC murC ddl ddl ftsQ ftsQ ftsZ ftsZ frr frr omp omp skp skp OSI07993.1 OSI07993.1 mlaC_2 mlaC_2 OSI07997.1 OSI07997.1 yidD yidD gyrB gyrB OSI07639.1 OSI07639.1 parE parE dacC dacC rplT rplT prfA prfA ypdA ypdA OSI07724.1 OSI07724.1 comM comM uppP uppP htrE htrE OSI07781.1 OSI07781.1 OSI07797.1 OSI07797.1 OSI07811.1 OSI07811.1 OSI07473.1 OSI07473.1 recD recD rep rep mfd mfd OSI07597.1 OSI07597.1 comL comL dnaB dnaB OSI07577.1 OSI07577.1 pilK pilK minC minC yrbA_2 yrbA_2 glmU glmU rlpA rlpA ruvA ruvA OSI07400.1 OSI07400.1 OSI07420.1 OSI07420.1 topA topA cyaY cyaY ybeB ybeB parC parC OSI07172.1 OSI07172.1 lptE lptE dipZ_2 dipZ_2 OSI07112.1 OSI07112.1 OSI07113.1 OSI07113.1 recC recC glr glr OSI07078.1 OSI07078.1 smpA smpA OSI06878.1 OSI06878.1 zapD zapD epsE epsE secB secB recG recG nagZ nagZ ygfZ ygfZ ypjD ypjD cas2 cas2 cas1 cas1 OSI06715.1 OSI06715.1 OSI06717.1 OSI06717.1 lptA lptA OSI06671.1 OSI06671.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (722 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (228 aa)
OSI08581.1Pilin assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
pilOPilus assembly protein PilO; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
OSI08583.1Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
mrcAPeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (813 aa)
engBYihA family ribosome biogenesis GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (206 aa)
ccsBCytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
OSI08588.1C-type cytochrome biogenesis protein CcsB; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
yafQYafQ family addiction module toxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
dipZ_1Protein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (599 aa)
prsA1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
lptDLPS biosynthesis protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (776 aa)
OSI08799.1Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
mviNMurein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (514 aa)
OSI08846.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
pbpGD-alanyl-D-alanine endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (315 aa)
OSI08866.1Pilin; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. (112 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1164 aa)
OSI08974.1Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. (428 aa)
yceGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (331 aa)
pqiBParaquat-inducible protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
typAGTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
hscA_2Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
iscXFe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
recBExodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] (1205 aa)
OSI08228.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
narJNitrate reductase molybdenum cofactor assembly chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (532 aa)
mlaC_1Toluene tolerance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (369 aa)
penA_1Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (684 aa)
iscSIscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
nifUFe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (127 aa)
OSI08362.1Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
iscAIron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. (106 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (459 aa)
hupBDNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (89 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family. (131 aa)
ruvBHolliday junction branch migration DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (343 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (923 aa)
hscBFe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (167 aa)
pilT_2Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
dinGPeptide chain release factor 2; DNA-dependent ATPase and 5'-3' DNA helicase. (709 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa)
mltAMurein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
stoAThioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ylxHFe-S-binding ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (359 aa)
uvrDDNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
penA_2Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (583 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (491 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (454 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (445 aa)
ftsWPutative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (386 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (465 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (303 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (254 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (390 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
ompOuter membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (810 aa)
skpHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
OSI07993.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
mlaC_2Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
OSI07997.1Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
yidDMembrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (70 aa)
gyrBDNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] (797 aa)
OSI07639.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (660 aa)
dacCPeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (400 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (358 aa)
ypdASensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
OSI07724.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
comMATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (275 aa)
htrEHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (821 aa)
OSI07781.1Phytochrome sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
OSI07797.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
OSI07811.1Pilus assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
OSI07473.1Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (589 aa)
repDNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (670 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; Belongs to the UvrB family. In the N-terminal section; belongs to the UvrB family. (1161 aa)
OSI07597.1Ribosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
comLOuter membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (267 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (469 aa)
OSI07577.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
pilKPilus assembly protein PilX; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (233 aa)
yrbA_2BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (83 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa)
rlpAHypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (239 aa)
ruvAHolliday junction branch migration protein RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (194 aa)
OSI07400.1Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
OSI07420.1traS protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (775 aa)
cyaYIron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (107 aa)
ybeBRibosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (131 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (769 aa)
OSI07172.1LemA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
lptEHypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (156 aa)
dipZ_2Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
OSI07112.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
OSI07113.1Prepilin-type N-terminal cleavage/methylation domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
recCExodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1071 aa)
glrGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (269 aa)
OSI07078.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (296 aa)
smpAOuter membrane assembly protein BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (129 aa)
OSI06878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (62 aa)
zapDCell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (255 aa)
epsEType IV-A pilus assembly ATPase PilB; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
secBProtein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (144 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (679 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (361 aa)
ygfZFolate-binding protein YgfZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (286 aa)
ypjDSignal transduction protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
cas2CRISPR-associated endonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (97 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (297 aa)
OSI06715.1Type I-C CRISPR-associated protein Cas7/Csd2; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
OSI06717.1Type I-C CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (173 aa)
OSI06671.1YihA family ribosome biogenesis GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
Your Current Organism:
Neisseria animaloris
NCBI taxonomy Id: 326522
Other names: ATCC 29858, CDC D8251, DSM 21642, LMG 23011, LMG:23011, N. animaloris, NCTC 12228, Neisseria animaloris Vandamme et al. 2006, Neisseria sp. EF-4a, Neisseria sp. R-24680, strain CL 191/78
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