STRINGSTRING
ENSGAFP00000000238 ENSGAFP00000000238 ENSGAFP00000000816 ENSGAFP00000000816 CCH79_00000477 CCH79_00000477 CCH79_00016412 CCH79_00016412 CCH79_00001126 CCH79_00001126 CCH79_00010690 CCH79_00010690 CCH79_00005816 CCH79_00005816 NT5C3B NT5C3B PDE1C PDE1C ENSGAFP00000002254 ENSGAFP00000002254 CCH79_00018312 CCH79_00018312 CCH79_00000504 CCH79_00000504 ENSGAFP00000002821 ENSGAFP00000002821 NT5M NT5M CCH79_00016791 CCH79_00016791 CCH79_00016795 CCH79_00016795 CCH79_00003659 CCH79_00003659 CCH79_00000671 CCH79_00000671 IMPDH IMPDH CCH79_00000014 CCH79_00000014 GMPR GMPR ENSGAFP00000004993 ENSGAFP00000004993 CCH79_00013570 CCH79_00013570 ENTPD7 ENTPD7 IMPDH-2 IMPDH-2 ENSGAFP00000007419 ENSGAFP00000007419 CCH79_00018956 CCH79_00018956 CCH79_00002023 CCH79_00002023 ADK ADK CCH79_00019340 CCH79_00019340 ENSGAFP00000008902 ENSGAFP00000008902 CCH79_00012330 CCH79_00012330 CCH79_00011820 CCH79_00011820 ITPA ITPA CCH79_00008383 CCH79_00008383 CCH79_00008384 CCH79_00008384 AK3 AK3 CCH79_00000824 CCH79_00000824 CCH79_00001587 CCH79_00001587 CCH79_00000151 CCH79_00000151 CCH79_00006034 CCH79_00006034 AK3-2 AK3-2 CCH79_00020729 CCH79_00020729 CCH79_00016640 CCH79_00016640 ENSGAFP00000014121 ENSGAFP00000014121 CCH79_00020065 CCH79_00020065 CCH79_00003184 CCH79_00003184 CCH79_00017305 CCH79_00017305 CCH79_00008766 CCH79_00008766 GMPR-2 GMPR-2 CCH79_00000373 CCH79_00000373 CCH79_00004460 CCH79_00004460 CCH79_00012711 CCH79_00012711 CCH79_00002887 CCH79_00002887 CCH79_00010793 CCH79_00010793 CCH79_00000962 CCH79_00000962 CCH79_00011330 CCH79_00011330 CCH79_00018683 CCH79_00018683 CCH79_00003881 CCH79_00003881 CCH79_00010283 CCH79_00010283 CCH79_00016994 CCH79_00016994 CCH79_00012740 CCH79_00012740 CCH79_00019848 CCH79_00019848 ENSGAFP00000019298 ENSGAFP00000019298 CCH79_00002123 CCH79_00002123 CCH79_00007112 CCH79_00007112 CCH79_00013901 CCH79_00013901 CCH79_00013014 CCH79_00013014 CCH79_00013525 CCH79_00013525 CCH79_00009978 CCH79_00009978 CCH79_00008183 CCH79_00008183 CCH79_00017885 CCH79_00017885 CCH79_00004505 CCH79_00004505 CCH79_00011036 CCH79_00011036 ENSGAFP00000025098 ENSGAFP00000025098 CCH79_00010376 CCH79_00010376 CCH79_00019233 CCH79_00019233 CCH79_00011105 CCH79_00011105 ADSSL1 ADSSL1 CCH79_00006334 CCH79_00006334 CCH79_00015232 CCH79_00015232 CCH79_00004615 CCH79_00004615 CCH79_00009097 CCH79_00009097 CCH79_00008572 CCH79_00008572 CCH79_00018493 CCH79_00018493 ENSGAFP00000029056 ENSGAFP00000029056 ENSGAFP00000031113 ENSGAFP00000031113 CCH79_00009721 CCH79_00009721 CCH79_00005405 CCH79_00005405 ENSGAFP00000032113 ENSGAFP00000032113 CCH79_00010103 CCH79_00010103 CCH79_00016145 CCH79_00016145 CCH79_00017147 CCH79_00017147
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGAFP00000000238Ectonucleoside triphosphate diphosphohydrolase 3. (500 aa)
ENSGAFP00000000816Adenylosuccinate synthase 2. (522 aa)
CCH79_00000477Uncharacterized protein. (862 aa)
CCH79_00016412Nudix hydrolase domain-containing protein. (228 aa)
CCH79_00001126dNK domain-containing protein. (263 aa)
CCH79_00010690AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (787 aa)
CCH79_00005816Pribosyltran domain-containing protein. (218 aa)
NT5C3BUncharacterized protein. (303 aa)
PDE1CPhosphodiesterase. (576 aa)
ENSGAFP00000002254Purine nucleoside phosphorylase 5a. (294 aa)
CCH79_00018312Uncharacterized protein. (570 aa)
CCH79_00000504Uncharacterized protein. (361 aa)
ENSGAFP00000002821annotation not available (824 aa)
NT5MUncharacterized protein. (230 aa)
CCH79_00016791CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (588 aa)
CCH79_00016795Uncharacterized protein. (442 aa)
CCH79_00003659Uncharacterized protein. (690 aa)
CCH79_00000671Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (502 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
CCH79_00000014Nucleoside diphosphate kinase. (185 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (381 aa)
ENSGAFP00000004993Ectonucleoside triphosphate diphosphohydrolase 6. (431 aa)
CCH79_00013570Nucleoside diphosphate kinase. (239 aa)
ENTPD7Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (604 aa)
IMPDH-2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (626 aa)
ENSGAFP00000007419NME/NM23 nucleoside diphosphate kinase 3. (168 aa)
CCH79_00018956A_deaminase domain-containing protein. (617 aa)
CCH79_00002023Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
ADKAdenosine kinase. (365 aa)
CCH79_00019340Uncharacterized protein. (160 aa)
ENSGAFP00000008902Ectonucleotide pyrophosphatase/phosphodiesterase 4. (455 aa)
CCH79_00012330Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (215 aa)
CCH79_00011820AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (773 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (184 aa)
CCH79_00008383Uncharacterized protein. (604 aa)
CCH79_00008384Uncharacterized protein. (425 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
CCH79_00000824Uncharacterized protein. (480 aa)
CCH79_00001587PfkB domain-containing protein. (371 aa)
CCH79_00000151Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (428 aa)
CCH79_00006034NDK domain-containing protein; Belongs to the NDK family. (210 aa)
AK3-2GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (226 aa)
CCH79_00020729Metallophos domain-containing protein; Belongs to the 5'-nucleotidase family. (608 aa)
CCH79_00016640Guanylate kinase-like domain-containing protein. (734 aa)
ENSGAFP00000014121Ectonucleoside triphosphate diphosphohydrolase 4. (618 aa)
CCH79_00020065Uncharacterized protein; Belongs to the adenylate kinase family. (457 aa)
CCH79_00003184Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (497 aa)
CCH79_00017305Pribosyltran domain-containing protein. (181 aa)
CCH79_00008766Uncharacterized protein. (354 aa)
GMPR-2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
CCH79_00000373Uncharacterized protein. (1693 aa)
CCH79_00004460Uncharacterized protein. (662 aa)
CCH79_00012711Uncharacterized protein. (446 aa)
CCH79_00002887Uncharacterized protein. (492 aa)
CCH79_000107935'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (334 aa)
CCH79_00000962Uncharacterized protein; Belongs to the adenylate kinase family. (189 aa)
CCH79_00011330Phosphodiesterase. (735 aa)
CCH79_00018683A_deaminase domain-containing protein. (348 aa)
CCH79_00003881Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (794 aa)
CCH79_00010283Pribosyltran domain-containing protein. (200 aa)
CCH79_00016994Phosphodiesterase. (434 aa)
CCH79_00012740Uncharacterized protein. (558 aa)
CCH79_00019848PNP_UDP_1 domain-containing protein. (277 aa)
ENSGAFP00000019298annotation not available (519 aa)
CCH79_00002123Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (473 aa)
CCH79_00007112Guanylate kinase-like domain-containing protein. (194 aa)
CCH79_00013901Uncharacterized protein. (161 aa)
CCH79_00013014Uncharacterized protein. (505 aa)
CCH79_00013525Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (915 aa)
CCH79_00009978Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (500 aa)
CCH79_00008183Phosphodiesterase. (746 aa)
CCH79_00017885Uncharacterized protein. (234 aa)
CCH79_00004505Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (420 aa)
CCH79_00011036Uridine-cytidine kinase; Belongs to the uridine kinase family. (262 aa)
ENSGAFP00000025098IMP (inosine 5'-monophosphate) dehydrogenase 1b. (613 aa)
CCH79_00010376A_deaminase domain-containing protein. (758 aa)
CCH79_00019233NDK domain-containing protein; Belongs to the NDK family. (149 aa)
CCH79_00011105DM10 domain-containing protein; Belongs to the NDK family. (374 aa)
ADSSL1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
CCH79_00006334HD domain-containing protein. (179 aa)
CCH79_00015232A_deaminase_N domain-containing protein. (355 aa)
CCH79_00004615Uncharacterized protein. (366 aa)
CCH79_00009097dNK domain-containing protein. (320 aa)
CCH79_00008572Uncharacterized protein. (387 aa)
CCH79_00018493Uncharacterized protein. (393 aa)
ENSGAFP00000029056Adenylate kinase 2. (240 aa)
ENSGAFP00000031113Adenylate kinase 5. (549 aa)
CCH79_00009721Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
CCH79_00005405Guanylate kinase-like domain-containing protein. (199 aa)
ENSGAFP00000032113Adenosine monophosphate deaminase 2a. (801 aa)
CCH79_00010103PNP_UDP_1 domain-containing protein. (297 aa)
CCH79_00016145dNK domain-containing protein. (266 aa)
CCH79_00017147Phosphodiesterase. (516 aa)
Your Current Organism:
Gambusia affinis
NCBI taxonomy Id: 33528
Other names: G. affinis, western mosquitofish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.