(18 nodes) Butanoate metabolism network (Uncinocarpus reesii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	UREG_02628	Uncharacterized protein. (402 aa)
	UREG_02742	Succinate-semialdehyde dehydrogenase. (531 aa)
	UREG_01473	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	UREG_01583	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
	UREG_01846	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (499 aa)
	UREG_03759	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
	UREG_04369	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (494 aa)
	UREG_02971	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
	UREG_03016	Glutamate decarboxylase 1. (286 aa)
	UREG_03325	Acetoacetate-CoA ligase. (712 aa)
	UREG_05484	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (500 aa)
	UREG_06007	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (439 aa)
	UREG_06791	Acetolactate synthase small subunit. (303 aa)
	UREG_06412	Pyruvate carboxyltransferase domain-containing protein. (363 aa)
	UREG_07181	Acetoacetate-CoA ligase. (670 aa)
	UREG_07363	Acetolactate synthase. (684 aa)
	UREG_07400	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (446 aa)
	UREG_07483	Uncharacterized protein. (550 aa)

Your Current Organism:

Uncinocarpus reesii

NCBI taxonomy Id: 336963
Other names: U. reesii 1704, Uncinocarpus reesii 1704

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UREG_01473	UREG_01583	C4JID6	C4JIX6	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.744
UREG_01473	UREG_02628	C4JID6	C4JH55	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.988
UREG_01473	UREG_02971	C4JID6	C4JNH3	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.904
UREG_01473	UREG_03325	C4JID6	C4JQI0	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetate-CoA ligase.	0.949
UREG_01473	UREG_05484	C4JID6	C4JSP5	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.956
UREG_01473	UREG_06412	C4JID6	C4JXN9	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate carboxyltransferase domain-containing protein.	0.933
UREG_01473	UREG_07181	C4JID6	C4JYD0	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetate-CoA ligase.	0.949
UREG_01473	UREG_07400	C4JID6	C4JYZ9	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.994
UREG_01583	UREG_01473	C4JIX6	C4JID6	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.744
UREG_01583	UREG_02628	C4JIX6	C4JH55	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.998
UREG_01583	UREG_02971	C4JIX6	C4JNH3	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.717
UREG_01583	UREG_03325	C4JIX6	C4JQI0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetoacetate-CoA ligase.	0.430
UREG_01583	UREG_05484	C4JIX6	C4JSP5	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.491
UREG_01583	UREG_06412	C4JIX6	C4JXN9	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Pyruvate carboxyltransferase domain-containing protein.	0.603
UREG_01583	UREG_07181	C4JIX6	C4JYD0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetoacetate-CoA ligase.	0.430
UREG_01583	UREG_07400	C4JIX6	C4JYZ9	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.428
UREG_01846	UREG_02742	C4JJN9	C4JHQ6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Succinate-semialdehyde dehydrogenase.	0.903
UREG_01846	UREG_03016	C4JJN9	C4JNL8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Glutamate decarboxylase 1.	0.447
UREG_01846	UREG_03325	C4JJN9	C4JQI0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Acetoacetate-CoA ligase.	0.470
UREG_01846	UREG_04369	C4JJN9	C4JNG3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.964