(33 nodes) Positive regulation of nitric oxide biosynthetic process network (Colobus angolensis)

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second shell of interactors

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Predicted Interactions

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Your Input:
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (262 aa)
	ENSCANP00000032715	Uncharacterized protein. (321 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
	AGTR2	Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (840 aa)
	TICAM1	Toll like receptor adaptor molecule 1. (517 aa)
	ASL	Argininosuccinate lyase. (464 aa)
	NOS1AP	Nitric oxide synthase 1 adaptor protein. (506 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (780 aa)
	CLU	Clusterin. (534 aa)
	KLRK1	Killer cell lectin like receptor K1. (216 aa)
	ENSCANP00000038566	Uncharacterized protein. (400 aa)
	PTX3	Pentraxin 3. (381 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	INSR	Tyrosine-protein kinase receptor. (1388 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
	ITGB2	Integrin beta. (769 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
	P2RX4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (383 aa)
	CLEC7A	C-type lectin domain containing 7A. (247 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	MMP8	Matrix metallopeptidase 8. (467 aa)
	ASS1	Argininosuccinate synthase 1. (391 aa)
	KLF4	Kruppel like factor 4. (479 aa)
	ENSCANP00000002057	Uncharacterized protein. (147 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	DDAH2	Dimethylarginine dimethylaminohydrolase 2. (285 aa)
	ENSCANP00000020568	Uncharacterized protein. (455 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT2	ASL	ENSCANP00000015608	ENSCANP00000026305	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Argininosuccinate lyase.	0.426
AGXT2	DDAH1	ENSCANP00000015608	ENSCANP00000032782	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dimethylarginine dimethylaminohydrolase 1.	0.720
AGXT2	DDAH2	ENSCANP00000015608	ENSCANP00000000881	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dimethylarginine dimethylaminohydrolase 2.	0.636
AKT1	ESR1	ENSCANP00000014683	ENSCANP00000036203	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.560
AKT1	IFNG	ENSCANP00000014683	ENSCANP00000014463	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.466
AKT1	IL1B	ENSCANP00000014683	ENSCANP00000031282	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.543
AKT1	KLF4	ENSCANP00000014683	ENSCANP00000006792	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Kruppel like factor 4.	0.439
AKT1	PTGS2	ENSCANP00000014683	ENSCANP00000019153	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Prostaglandin-endoperoxide synthase 2.	0.409
AKT1	SMAD3	ENSCANP00000014683	ENSCANP00000000895	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.768
AKT1	TLR4	ENSCANP00000014683	ENSCANP00000028903	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.457
ASL	AGXT2	ENSCANP00000026305	ENSCANP00000015608	Argininosuccinate lyase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.426
ASL	ASS1	ENSCANP00000026305	ENSCANP00000007846	Argininosuccinate lyase.	Argininosuccinate synthase 1.	0.984
ASL	DDAH1	ENSCANP00000026305	ENSCANP00000032782	Argininosuccinate lyase.	Dimethylarginine dimethylaminohydrolase 1.	0.546
ASL	DDAH2	ENSCANP00000026305	ENSCANP00000000881	Argininosuccinate lyase.	Dimethylarginine dimethylaminohydrolase 2.	0.544
ASL	ENSCANP00000020568	ENSCANP00000026305	ENSCANP00000020568	Argininosuccinate lyase.	Uncharacterized protein.	0.983
ASL	ENSCANP00000032715	ENSCANP00000026305	ENSCANP00000032715	Argininosuccinate lyase.	Uncharacterized protein.	0.984
ASL	ENSCANP00000038566	ENSCANP00000026305	ENSCANP00000038566	Argininosuccinate lyase.	Uncharacterized protein.	0.984
ASS1	ASL	ENSCANP00000007846	ENSCANP00000026305	Argininosuccinate synthase 1.	Argininosuccinate lyase.	0.984
ASS1	ENSCANP00000020568	ENSCANP00000007846	ENSCANP00000020568	Argininosuccinate synthase 1.	Uncharacterized protein.	0.402
CD36	CLEC7A	ENSCANP00000033730	ENSCANP00000012446	CD36 molecule; Belongs to the CD36 family.	C-type lectin domain containing 7A.	0.400