STRINGSTRING
Maqu_3128 Maqu_3128 Maqu_0008 Maqu_0008 Maqu_3127 Maqu_3127 Maqu_3126 Maqu_3126 Maqu_1823 Maqu_1823 Maqu_1818 Maqu_1818 Maqu_0254 Maqu_0254 Maqu_0321 Maqu_0321 Maqu_0356 Maqu_0356 Maqu_0381 Maqu_0381 Maqu_3026 Maqu_3026 Maqu_0449 Maqu_0449 Maqu_0450 Maqu_0450 Maqu_0451 Maqu_0451 Maqu_0457 Maqu_0457 Maqu_0470 Maqu_0470 Maqu_0475 Maqu_0475 Maqu_0617 Maqu_0617 rpoZ rpoZ secE secE Maqu_3632 Maqu_3632 Maqu_3636 Maqu_3636 Maqu_3645 Maqu_3645 Maqu_3646 Maqu_3646 Maqu_3797 Maqu_3797 tpx tpx Maqu_3838 Maqu_3838 Maqu_1753 Maqu_1753 msbA msbA rpoB rpoB rpoC rpoC tuf tuf secY secY rpoA rpoA Maqu_0747 Maqu_0747 Maqu_0773 Maqu_0773 Maqu_0843 Maqu_0843 Maqu_0915 Maqu_0915 katG katG Maqu_1070 Maqu_1070 secD secD secF secF ndk ndk Maqu_1155 Maqu_1155 Maqu_1195 Maqu_1195 Maqu_1269 Maqu_1269 Maqu_1380 Maqu_1380 Maqu_1401 Maqu_1401 Maqu_1410 Maqu_1410 Maqu_1456 Maqu_1456 Maqu_1541 Maqu_1541 Maqu_1643 Maqu_1643 Maqu_1674 Maqu_1674 Maqu_1692 Maqu_1692 Maqu_1733 Maqu_1733 Maqu_1737 Maqu_1737 Maqu_2977 Maqu_2977 Maqu_2837 Maqu_2837 Maqu_2707 Maqu_2707 Maqu_2695 Maqu_2695 Maqu_2653 Maqu_2653 Maqu_2584 Maqu_2584 secA secA Maqu_2295 Maqu_2295 Maqu_2251 Maqu_2251 Maqu_2187 Maqu_2187 Maqu_2050 Maqu_2050 Maqu_2048 Maqu_2048 Maqu_2047 Maqu_2047 Maqu_2023 Maqu_2023 Maqu_0032 Maqu_0032 Maqu_0081 Maqu_0081 Maqu_0112 Maqu_0112 Maqu_3629 Maqu_3629 Maqu_3600 Maqu_3600 Maqu_3549 Maqu_3549 Maqu_0114 Maqu_0114 Maqu_3482 Maqu_3482 Maqu_3407 Maqu_3407 msrA msrA Maqu_3351 Maqu_3351 Maqu_3331 Maqu_3331 Maqu_3327 Maqu_3327 Maqu_3321 Maqu_3321 Maqu_3300 Maqu_3300 Maqu_3129 Maqu_3129
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Maqu_3128KEGG: tbd:Tbd_0073 possible transcriptional regulator, AsnC family. (166 aa)
Maqu_0008KEGG: pfl:PFL_1935 ABC transporter, ATP-binding/permease protein; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase. (590 aa)
Maqu_3127Transcriptional regulator, AsnC family; KEGG: cps:CPS_4224 putative heme biosynthesis protein. (178 aa)
Maqu_3126Transcriptional regulator, AsnC family; KEGG: pau:PA14_06710 heme d1 biosynthesis protein NirD. (154 aa)
Maqu_1823KEGG: hch:HCH_02592 hypothetical protein. (829 aa)
Maqu_1818Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: hch:HCH_02597 thiol-disulfide isomerase and thioredoxins. (165 aa)
Maqu_02541-Cys peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ppu:PP_0235 antioxidant protein LsfA. (217 aa)
Maqu_0321PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pau:PA14_17400 alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
Maqu_0356PFAM: luciferase family protein; KEGG: abo:ABO_0676 hypothetical protein. (339 aa)
Maqu_03811-Cys peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpb:RPB_3015 peroxidase. (208 aa)
Maqu_3026PFAM: major facilitator superfamily MFS_1; KEGG: xac:XAC1363 MFS transporter. (411 aa)
Maqu_0449PFAM: extracellular solute-binding protein, family 5; KEGG: csa:Csal_1873 extracellular solute-binding protein, family 5. (520 aa)
Maqu_0450PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_1872 binding-protein-dependent transport systems inner membrane component. (349 aa)
Maqu_0451PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_1871 binding-protein-dependent transport systems inner membrane component. (310 aa)
Maqu_0457Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (158 aa)
Maqu_0470Peptidylprolyl isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: hch:HCH_00278 FKBP-type peptidyl-prolyl cis-trans isomerases 1. (244 aa)
Maqu_0475TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pau:PA14_69200 thioredoxin; Belongs to the thioredoxin family. (108 aa)
Maqu_0617TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: hne:HNE_2405 drug resistance transporter, EmrB/QacA family. (543 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (70 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (122 aa)
Maqu_3632PFAM: major facilitator superfamily MFS_1; KEGG: ilo:IL2408 permease of the major facilitator superfamily. (391 aa)
Maqu_3636PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_4001 major facilitator superfamily MFS_1. (403 aa)
Maqu_3645KEGG: sdn:Sden_1599 hypothetical protein. (401 aa)
Maqu_3646KEGG: sdn:Sden_1598 ABC-type phosphate transport system, periplasmic component. (137 aa)
Maqu_3797TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: mag:amb0291 permease of the major facilitator superfamily. (405 aa)
tpxThiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (165 aa)
Maqu_3838Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
Maqu_1753TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: hch:HCH_02344 thioredoxin-disulfide reductase. (317 aa)
msbALipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (590 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1358 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1404 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (398 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (440 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (334 aa)
Maqu_0747PFAM: major facilitator superfamily MFS_1; KEGG: hch:HCH_06190 permease of the major facilitator superfamily. (456 aa)
Maqu_0773KEGG: hch:HCH_01041 outer membrane protein (porin). (333 aa)
Maqu_0843Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (363 aa)
Maqu_0915PFAM: Redoxin domain protein; KEGG: ppu:PP_1646 thioredoxin, putative. (158 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (723 aa)
Maqu_1070Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (153 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (624 aa)
secFProtein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (316 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa)
Maqu_11552-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa)
Maqu_1195PFAM: Mammalian cell entry related domain protein; KEGG: pfo:Pfl_0039 hypothetical protein. (312 aa)
Maqu_1269PFAM: leucine-rich repeat protein; KEGG: lil:LA1530 leucine rich repeat protein. (360 aa)
Maqu_1380PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hch:HCH_03685 2-oxoglutarate dehydrogenase E2. (528 aa)
Maqu_1401PFAM: Redoxin domain protein; KEGG: pol:Bpro_3502 hypothetical protein. (191 aa)
Maqu_14101-Cys peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: psp:PSPPH_4906 antioxidant, AhpC/Tsa family. (212 aa)
Maqu_1456Hypothetical protein; KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein. (202 aa)
Maqu_1541PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: psp:PSPPH_1704 ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (541 aa)
Maqu_1643Hypothetical protein. (470 aa)
Maqu_1674PFAM: bifunctional deaminase-reductase domain protein; KEGG: csa:Csal_1173 bifunctional deaminase-reductase-like protein. (288 aa)
Maqu_1692PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ppu:PP_1235 AhpC/TSA family protein. (155 aa)
Maqu_1733PFAM: regulatory protein, AsnC/Lrp family; KEGG: hch:HCH_05144 transcriptional regulator. (165 aa)
Maqu_1737PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: pau:PA14_25540 phosphotyrosine protein phosphatase. (159 aa)
Maqu_2977TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: mfa:Mfla_1161 thioredoxin. (146 aa)
Maqu_2837KEGG: abo:ABO_2575 hypothetical protein. (437 aa)
Maqu_2707PFAM: Mammalian cell entry related domain protein; KEGG: hch:HCH_05312 ABC-type transport system involved in resistance to organic solvents, periplasmic component. (149 aa)
Maqu_2695PFAM: protein of unknown function DUF1302; KEGG: hch:HCH_05297 ABC-type dipeptide transport system, periplasmic component. (615 aa)
Maqu_2653Superoxide dismutase, copper/zinc binding protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (182 aa)
Maqu_2584PFAM: major facilitator superfamily MFS_1; KEGG: csa:Csal_2143 major facilitator superfamily MFS_1. (439 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (912 aa)
Maqu_2295PFAM: major facilitator superfamily MFS_1; KEGG: rpd:RPD_4124 major facilitator superfamily MFS_1. (402 aa)
Maqu_2251PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_2191 alcohol dehydrogenase, zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
Maqu_2187PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: noc:Noc_0115 ABC transporter, transmembrane region. (595 aa)
Maqu_2050PFAM: regulatory protein, AsnC/Lrp family; KEGG: sil:SPO3009 proline dehydrogenase transcriptional activator. (150 aa)
Maqu_2048PFAM: major facilitator superfamily MFS_1; KEGG: sco:SCO1709 integral membrane transport protein. (366 aa)
Maqu_2047PFAM: major facilitator superfamily MFS_1; KEGG: sit:TM1040_2672 major facilitator superfamily MFS_1. (421 aa)
Maqu_2023Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa)
Maqu_0032PFAM: S-type Pyocin domain protein; KEGG: vpa:VPA1263 hypothetical protein. (546 aa)
Maqu_0081KEGG: abo:ABO_0012 hypothetical protein. (470 aa)
Maqu_0112PFAM: major facilitator superfamily MFS_1; KEGG: sal:Sala_2954 major facilitator superfamily MFS_1. (427 aa)
Maqu_3629Phosphate ABC transporter substrate-binding protein, PhoT family; KEGG: abo:ABO_2685 phosphate ABC transporter periplasmic binding protein; TC 3.A.1.7.1. (349 aa)
Maqu_3600PFAM: protein of unknown function DUF1555; KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein. (245 aa)
Maqu_3549PFAM: von Willebrand factor, type A; protein of unknown function DUF1555; KEGG: ter:Tery_1039 hypothetical protein. (302 aa)
Maqu_0114TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: hch:HCH_05142 permease of the major facilitator superfamily. (463 aa)
Maqu_3482PFAM: porin, Gram-negative type; KEGG: ppr:PBPRA1012 OmpH porin-like protein H precursor. (318 aa)
Maqu_3407Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (192 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (216 aa)
Maqu_3351Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (127 aa)
Maqu_3331TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: hch:HCH_01258 thioredoxin domain-containing protein. (287 aa)
Maqu_3327Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (552 aa)
Maqu_3321KEGG: pha:PSHAa0696 hypothetical protein. (347 aa)
Maqu_3300TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: aeh:Mlg_1176 drug resistance transporter, Bcr/CflA subfamily. (400 aa)
Maqu_3129Transcriptional regulator, AsnC family; KEGG: sil:SPOA0226 nitrite reductase heme biosynthesis H protein. (173 aa)
Your Current Organism:
Marinobacter hydrocarbonoclasticus
NCBI taxonomy Id: 351348
Other names: M. hydrocarbonoclasticus VT8, Marinobacter aquaeolei VT8, Marinobacter aquaeolei str. VT8, Marinobacter aquaeolei strain VT8, Marinobacter hydrocarbonoclasticus VT8
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