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Acel_0467 Acel_0467 Acel_0521 Acel_0521 deoC deoC rbsK rbsK Acel_0721 Acel_0721 pfp pfp pgl pgl zwf zwf tal tal Acel_1127 Acel_1127 Acel_1213 Acel_1213 Acel_1214 Acel_1214 Acel_1276 Acel_1276 Acel_1598 Acel_1598 Acel_1681 Acel_1681 Acel_1820 Acel_1820 Acel_1877 Acel_1877 prs prs Acel_2125 Acel_2125
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Acel_0467PFAM: sugar isomerase (SIS); KEGG: fra:Francci3_0753 conserved hypothetical protein. (387 aa)
Acel_0521PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: fra:Francci3_3546 fructose-6-phosphate phosphoketolase. (797 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (235 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (313 aa)
Acel_0721PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sto:ST2350 hypothetical protein. (283 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (254 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (508 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
Acel_1127Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (692 aa)
Acel_1213TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: sco:SCO3495 putative 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase. (214 aa)
Acel_1214PFAM: PfkB domain protein; KEGG: sco:SCO3494 putative 2-dehydro-3-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family. (329 aa)
Acel_1276PFAM: ribulose-phosphate 3-epimerase; KEGG: tfu:Tfu_1077 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (229 aa)
Acel_1598Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: sco:SCO2627 putative sugar-phosphate isomerase. (160 aa)
Acel_1681PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: nfa:nfa35140 putative dehydrogenase. (350 aa)
Acel_1820TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: mpa:MAP2670c 6-phosphogluconate dehydrogenase. (344 aa)
Acel_1877TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein. (349 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
Acel_2125Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa)
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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