(16 nodes) Ribosome assembly network (Cryptosporidium parvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cgd8_4680	Conserved protein Py hit 23481194. (332 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (252 aa)
	cgd4_90	RRP7 domain-containing protein. (176 aa)
	cgd6_3960	Elongation factor-like protein. (1100 aa)
	cgd4_660	Nip7 like PUA domain containing protein involved in ribosomal biogenesis. (183 aa)
	cgd8_650	60S ribosomal protein L23A; Belongs to the universal ribosomal protein uL23 family. (156 aa)
	cgd4_1520	Brx1p nucleolar protein required for biogenesis of the 60S ribosomal subunit. (353 aa)
	cgd1_850	40S ribosomal protein S19. (154 aa)
	cgd4_2260	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa)
	cgd6_4320	40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (207 aa)
	cgd6_4190	60S ribosomal protein L10, alpha/beta hammerhead. (222 aa)
	cgd6_3180	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (152 aa)
	cgd7_4460	60S ribosomal protein L6. (184 aa)
	cgd7_1600	Ribosomal protein of the PO/L10 family. (222 aa)
	cgd8_3310	Ylr022cp-like protein that has a C2H2 zinc finger and is a component of the exosome. (379 aa)
	cgd3_2090	40S ribosomal protein SAe. (260 aa)

Your Current Organism:

Cryptosporidium parvum

NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF6	cgd1_850	Q5CQV5	Q5CSY3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	40S ribosomal protein S19.	0.762
EIF6	cgd3_2090	Q5CQV5	Q5CUN6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	40S ribosomal protein SAe.	0.619
EIF6	cgd4_1520	Q5CQV5	Q5CQA0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Brx1p nucleolar protein required for biogenesis of the 60S ribosomal subunit.	0.949
EIF6	cgd4_2260	Q5CQV5	Q5CR36	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.974
EIF6	cgd4_660	Q5CQV5	Q5CQH8	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Nip7 like PUA domain containing protein involved in ribosomal biogenesis.	0.960
EIF6	cgd6_3180	Q5CQV5	Q5CWZ0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.554
EIF6	cgd6_3960	Q5CQV5	A3FPW4	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Elongation factor-like protein.	0.868
EIF6	cgd6_4190	Q5CQV5	Q5CWQ2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S ribosomal protein L10, alpha/beta hammerhead.	0.996
EIF6	cgd6_4320	Q5CQV5	Q5CWP0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.620
EIF6	cgd7_1600	Q5CQV5	Q5CYP0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ribosomal protein of the PO/L10 family.	0.994
EIF6	cgd7_4460	Q5CQV5	Q5CXY3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S ribosomal protein L6.	0.994
EIF6	cgd8_3310	Q5CQV5	Q5CVP3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ylr022cp-like protein that has a C2H2 zinc finger and is a component of the exosome.	0.999
EIF6	cgd8_4680	Q5CQV5	Q5CVB6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Conserved protein Py hit 23481194.	0.973
EIF6	cgd8_650	Q5CQV5	Q5CPV5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S ribosomal protein L23A; Belongs to the universal ribosomal protein uL23 family.	0.995
cgd1_850	EIF6	Q5CSY3	Q5CQV5	40S ribosomal protein S19.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.762
cgd1_850	cgd3_2090	Q5CSY3	Q5CUN6	40S ribosomal protein S19.	40S ribosomal protein SAe.	0.999
cgd1_850	cgd4_2260	Q5CSY3	Q5CR36	40S ribosomal protein S19.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.999
cgd1_850	cgd4_660	Q5CSY3	Q5CQH8	40S ribosomal protein S19.	Nip7 like PUA domain containing protein involved in ribosomal biogenesis.	0.417
cgd1_850	cgd4_90	Q5CSY3	Q5CQM9	40S ribosomal protein S19.	RRP7 domain-containing protein.	0.964
cgd1_850	cgd6_3180	Q5CSY3	Q5CWZ0	40S ribosomal protein S19.	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.999