(39 nodes) Cargo adaptor activity, and Golgi Associated Vesicle Biogenesis network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_023452	Store-operated calcium entry-associated regulatory factor. (336 aa)
	APZ42_031704	AP-3 complex subunit sigma-2. (189 aa)
	APZ42_028247	Arf-GAP domain and FG repeat-containing 1-like protein. (499 aa)
	APZ42_026055	RalBP1-associated Eps domain-containing protein. (592 aa)
	APZ42_024908	AP-3 complex subunit delta-1. (1215 aa)
	APZ42_015608	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	APZ42_024201	AP-1 complex subunit gamma. (912 aa)
	APZ42_032183	Putative AP2-associated protein kinase. (692 aa)
	APZ42_020788	AP complex subunit beta. (927 aa)
	APZ42_020216	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_029329	Putative Huntingtin interacting protein 1. (1369 aa)
	APZ42_026018	Vesicle-associated membrane protein 7. (133 aa)
	APZ42_016099	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APZ42_015734	Uncharacterized protein. (263 aa)
	APZ42_015724	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1060 aa)
	APZ42_013830	Putative Stonin-1. (1840 aa)
	APZ42_013654	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	APZ42_011852	Amphiphysin. (341 aa)
	APZ42_011653	Bridging integrator 3. (269 aa)
	APZ42_003352	Coactosin-like protein. (162 aa)
	APZ42_003320	Putative Huntingtin-interacting protein 1. (187 aa)
	APZ42_002399	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (349 aa)
	APZ42_001089	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (118 aa)
	APZ42_000407	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (268 aa)
	APZ42_032189	Numb-associated kinase. (400 aa)
	APZ42_031695	Putative RalA-binding protein 1. (636 aa)
	APZ42_028960	Cyclin-G-associated kinase. (824 aa)
	APZ42_028262	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (95 aa)
	APZ42_028067	FCH domain only protein 2. (995 aa)
	APZ42_025631	Putative Amphiphysin. (139 aa)
	APZ42_024220	ADP ribosylation factor 6-like protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	APZ42_022686	Dynamin. (531 aa)
	APZ42_021745	Protein TBRG4. (602 aa)
	APZ42_021392	NECAP-like protein. (276 aa)
	APZ42_021443	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (415 aa)
	APZ42_019116	Phosphatidylinositol-binding clathrin assembly protein. (431 aa)
	APZ42_016707	Dynamin-binding protein. (1362 aa)
	APZ42_016272	Putative Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (523 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000407	APZ42_001089	A0A164JP86	A0A164J6I4	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.929
APZ42_000407	APZ42_002399	A0A164JP86	A0A164IAD9	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.445
APZ42_000407	APZ42_013654	A0A164JP86	A0A162QPP9	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.462
APZ42_000407	APZ42_015608	A0A164JP86	A0A0P5KQ01	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.929
APZ42_000407	APZ42_015724	A0A164JP86	A0A162NQ33	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.993
APZ42_000407	APZ42_016099	A0A164JP86	A0A162NMK5	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.494
APZ42_000407	APZ42_018911	A0A164JP86	A0A162CQ61	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.504
APZ42_000407	APZ42_020788	A0A164JP86	A0A0P6DXK2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.432
APZ42_000407	APZ42_021443	A0A164JP86	A0A164WPI1	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.696
APZ42_000407	APZ42_024201	A0A164JP86	A0A0P5LLS2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.937
APZ42_000407	APZ42_024908	A0A164JP86	A0A0P5HJ14	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit delta-1.	0.996
APZ42_000407	APZ42_031704	A0A164JP86	A0A0P4XAP2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit sigma-2.	0.988
APZ42_001089	APZ42_000407	A0A164J6I4	A0A164JP86	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.929
APZ42_001089	APZ42_015608	A0A164J6I4	A0A0P5KQ01	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.894
APZ42_001089	APZ42_015724	A0A164J6I4	A0A162NQ33	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.990
APZ42_001089	APZ42_021443	A0A164J6I4	A0A164WPI1	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.544
APZ42_001089	APZ42_024201	A0A164J6I4	A0A0P5LLS2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.905
APZ42_001089	APZ42_024908	A0A164J6I4	A0A0P5HJ14	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit delta-1.	0.995
APZ42_001089	APZ42_031704	A0A164J6I4	A0A0P4XAP2	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit sigma-2.	0.982
APZ42_002399	APZ42_000407	A0A164IAD9	A0A164JP86	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.445