(12 nodes) Intrinsic Pathway for Apoptosis, and Peptidase family C14A, His active site network (Daphnia magna)

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Your Input:
	APZ42_020472	Apoptosis regulator BAX. (210 aa)
	APZ42_018637	Apoptosis regulator R1. (193 aa)
	APZ42_026256	Caspase-1; Belongs to the peptidase C14A family. (323 aa)
	APZ42_020714	Caspase-1; Belongs to the peptidase C14A family. (298 aa)
	APZ42_016000	Putative Inactive caspase-12; Belongs to the peptidase C14A family. (513 aa)
	APZ42_026239	Caspase Dronc; Belongs to the peptidase C14A family. (466 aa)
	APZ42_016016	Receptor-interacting serine/threonine-protein kinase. (216 aa)
	APZ42_013204	Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	APZ42_012379	Apoptotic Protease-activating factor 1. (1391 aa)
	APZ42_012138	Baculoviral IAP repeat-containing protein 8. (505 aa)
	APZ42_026254	Inactive caspase-12; Belongs to the peptidase C14A family. (435 aa)
	APZ42_020051	Death-associated inhibitor of apoptosis 1. (405 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_012138	APZ42_012379	A0A162S4Z3	A0A162RRZ9	Baculoviral IAP repeat-containing protein 8.	Apoptotic Protease-activating factor 1.	0.845
APZ42_012138	APZ42_013204	A0A162S4Z3	A0A162R4J2	Baculoviral IAP repeat-containing protein 8.	Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.703
APZ42_012138	APZ42_016000	A0A162S4Z3	A0A0P6BWB8	Baculoviral IAP repeat-containing protein 8.	Putative Inactive caspase-12; Belongs to the peptidase C14A family.	0.860
APZ42_012138	APZ42_016016	A0A162S4Z3	A0A162NIB1	Baculoviral IAP repeat-containing protein 8.	Receptor-interacting serine/threonine-protein kinase.	0.830
APZ42_012138	APZ42_020714	A0A162S4Z3	A0A0P5U3K2	Baculoviral IAP repeat-containing protein 8.	Caspase-1; Belongs to the peptidase C14A family.	0.897
APZ42_012138	APZ42_026239	A0A162S4Z3	A0A162DB86	Baculoviral IAP repeat-containing protein 8.	Caspase Dronc; Belongs to the peptidase C14A family.	0.969
APZ42_012138	APZ42_026254	A0A162S4Z3	A0A164SB35	Baculoviral IAP repeat-containing protein 8.	Inactive caspase-12; Belongs to the peptidase C14A family.	0.861
APZ42_012138	APZ42_026256	A0A162S4Z3	A0A0P5SHQ9	Baculoviral IAP repeat-containing protein 8.	Caspase-1; Belongs to the peptidase C14A family.	0.897
APZ42_012379	APZ42_012138	A0A162RRZ9	A0A162S4Z3	Apoptotic Protease-activating factor 1.	Baculoviral IAP repeat-containing protein 8.	0.845
APZ42_012379	APZ42_013204	A0A162RRZ9	A0A162R4J2	Apoptotic Protease-activating factor 1.	Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APZ42_012379	APZ42_016000	A0A162RRZ9	A0A0P6BWB8	Apoptotic Protease-activating factor 1.	Putative Inactive caspase-12; Belongs to the peptidase C14A family.	0.986
APZ42_012379	APZ42_018637	A0A162RRZ9	A0A0P5E6Z1	Apoptotic Protease-activating factor 1.	Apoptosis regulator R1.	0.983
APZ42_012379	APZ42_020051	A0A162RRZ9	A0A164XYG1	Apoptotic Protease-activating factor 1.	Death-associated inhibitor of apoptosis 1.	0.845
APZ42_012379	APZ42_020472	A0A162RRZ9	A0A0P4XHJ8	Apoptotic Protease-activating factor 1.	Apoptosis regulator BAX.	0.983
APZ42_012379	APZ42_020714	A0A162RRZ9	A0A0P5U3K2	Apoptotic Protease-activating factor 1.	Caspase-1; Belongs to the peptidase C14A family.	0.986
APZ42_012379	APZ42_026239	A0A162RRZ9	A0A162DB86	Apoptotic Protease-activating factor 1.	Caspase Dronc; Belongs to the peptidase C14A family.	0.986
APZ42_012379	APZ42_026254	A0A162RRZ9	A0A164SB35	Apoptotic Protease-activating factor 1.	Inactive caspase-12; Belongs to the peptidase C14A family.	0.986
APZ42_012379	APZ42_026256	A0A162RRZ9	A0A0P5SHQ9	Apoptotic Protease-activating factor 1.	Caspase-1; Belongs to the peptidase C14A family.	0.986
APZ42_013204	APZ42_012138	A0A162R4J2	A0A162S4Z3	Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Baculoviral IAP repeat-containing protein 8.	0.703
APZ42_013204	APZ42_012379	A0A162R4J2	A0A162RRZ9	Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptotic Protease-activating factor 1.	0.999