(16 nodes) Regulation of transcription initiation from RNA polymerase II promoter network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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Your Input:
	APZ42_024804	Putative Serine/arginine-rich splicing factor 4. (363 aa)
	APZ42_013664	Putative Serine/arginine-rich splicing factor 2. (235 aa)
	APZ42_021683	Putative RNA-binding protein 1. (164 aa)
	APZ42_026413	RNA polymerase II transcriptional coactivator. (125 aa)
	APZ42_026665	Putative Splicing factor. (546 aa)
	APZ42_027885	Putative Serine/arginine-rich splicing factor 3. (233 aa)
	APZ42_032631	High mobility group protein DSP1. (190 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (818 aa)
	APZ42_034375	26S Protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
	APZ42_000020	Serine/arginine-rich splicing factor 1. (209 aa)
	APZ42_013766	Putative Nuclear pore complex protein Nup98-Nup96. (224 aa)
	APZ42_015656	Putative Transcription initiation factor TFIID subunit 3. (928 aa)
	EOG090X07N7	SEC13 protein; Belongs to the WD repeat SEC13 family. (311 aa)
	APZ42_022227	Nuclear pore complex protein Nup98-Nup96. (1843 aa)
	APZ42_021634	Serine/arginine-rich splicing factor. (162 aa)
	APZ42_016661	DNA excision repair ERCC-6-like protein. (1184 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000020	APZ42_013664	A0A164JZ53	A0A0P4XPR5	Serine/arginine-rich splicing factor 1.	Putative Serine/arginine-rich splicing factor 2.	0.998
APZ42_000020	APZ42_021634	A0A164JZ53	A0A0P6G7H0	Serine/arginine-rich splicing factor 1.	Serine/arginine-rich splicing factor.	0.990
APZ42_000020	APZ42_021683	A0A164JZ53	A0A164WGL2	Serine/arginine-rich splicing factor 1.	Putative RNA-binding protein 1.	0.990
APZ42_000020	APZ42_024804	A0A164JZ53	A0A0P5SZT8	Serine/arginine-rich splicing factor 1.	Putative Serine/arginine-rich splicing factor 4.	0.952
APZ42_000020	APZ42_026665	A0A164JZ53	A0A164S316	Serine/arginine-rich splicing factor 1.	Putative Splicing factor.	0.832
APZ42_000020	APZ42_027885	A0A164JZ53	A0A164QZJ7	Serine/arginine-rich splicing factor 1.	Putative Serine/arginine-rich splicing factor 3.	0.995
APZ42_013664	APZ42_000020	A0A0P4XPR5	A0A164JZ53	Putative Serine/arginine-rich splicing factor 2.	Serine/arginine-rich splicing factor 1.	0.998
APZ42_013664	APZ42_021634	A0A0P4XPR5	A0A0P6G7H0	Putative Serine/arginine-rich splicing factor 2.	Serine/arginine-rich splicing factor.	0.988
APZ42_013664	APZ42_021683	A0A0P4XPR5	A0A164WGL2	Putative Serine/arginine-rich splicing factor 2.	Putative RNA-binding protein 1.	0.988
APZ42_013664	APZ42_024804	A0A0P4XPR5	A0A0P5SZT8	Putative Serine/arginine-rich splicing factor 2.	Putative Serine/arginine-rich splicing factor 4.	0.968
APZ42_013664	APZ42_026665	A0A0P4XPR5	A0A164S316	Putative Serine/arginine-rich splicing factor 2.	Putative Splicing factor.	0.940
APZ42_013664	APZ42_027885	A0A0P4XPR5	A0A164QZJ7	Putative Serine/arginine-rich splicing factor 2.	Putative Serine/arginine-rich splicing factor 3.	0.983
APZ42_013766	APZ42_016661	A0A162QIP0	A0A165A3J8	Putative Nuclear pore complex protein Nup98-Nup96.	DNA excision repair ERCC-6-like protein.	0.501
APZ42_013766	EOG090X07N7	A0A162QIP0	A0A162DGD4	Putative Nuclear pore complex protein Nup98-Nup96.	SEC13 protein; Belongs to the WD repeat SEC13 family.	0.989
APZ42_015656	APZ42_032631	A0A162NTQ4	A0A164LRC4	Putative Transcription initiation factor TFIID subunit 3.	High mobility group protein DSP1.	0.606
APZ42_015656	MED16	A0A162NTQ4	A0A164LGT9	Putative Transcription initiation factor TFIID subunit 3.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.550
APZ42_016661	APZ42_013766	A0A165A3J8	A0A162QIP0	DNA excision repair ERCC-6-like protein.	Putative Nuclear pore complex protein Nup98-Nup96.	0.501
APZ42_016661	APZ42_022227	A0A165A3J8	A0A0P5EGA2	DNA excision repair ERCC-6-like protein.	Nuclear pore complex protein Nup98-Nup96.	0.501
APZ42_016661	APZ42_032631	A0A165A3J8	A0A164LRC4	DNA excision repair ERCC-6-like protein.	High mobility group protein DSP1.	0.621
APZ42_021634	APZ42_000020	A0A0P6G7H0	A0A164JZ53	Serine/arginine-rich splicing factor.	Serine/arginine-rich splicing factor 1.	0.990