(19 nodes) Proteasome regulatory particle, and Proteasome alpha-type subunit network (Stomoxys calcitrans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1I8NWN8	AAA domain-containing protein; Belongs to the AAA ATPase family. (427 aa)
	A0A1I8NXP0	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1016 aa)
	A0A1I8P7W1	PCI domain-containing protein. (495 aa)
	A0A1I8P822	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	A0A1I8PG97	MPN domain-containing protein. (335 aa)
	A0A1I8PR45	Proteasome subunit beta. (204 aa)
	A0A1I8PS14	PCI domain-containing protein. (389 aa)
	A0A1I8PUH6	AAA domain-containing protein; Belongs to the AAA ATPase family. (396 aa)
	A0A1I8PXP9	PCI domain-containing protein. (265 aa)
	A0A1I8PYP0	PCI domain-containing protein. (491 aa)
	A0A1I8Q094	VWFA domain-containing protein. (389 aa)
	A0A1I8Q7G3	AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
	A0A1I8Q7I4	AAA domain-containing protein; Belongs to the AAA ATPase family. (404 aa)
	A0A1I8Q9L7	PCI domain-containing protein. (421 aa)
	A0A1I8QC34	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (242 aa)
	A0A1I8QC76	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (909 aa)
	A0A1I8QDQ4	PCI domain-containing protein. (382 aa)
	A0A1I8QE54	MPN domain-containing protein. (308 aa)
	A0A1I8QF75	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)

Your Current Organism:

Stomoxys calcitrans

NCBI taxonomy Id: 35570
Other names: S. calcitrans, Stomoxis calcitrans, biting house fly, stable fly

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1I8NWN8	A0A1I8NXP0	AAA domain-containing protein; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.999
A0A1I8NWN8	A0A1I8P7W1	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8P822	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
A0A1I8NWN8	A0A1I8PG97	AAA domain-containing protein; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8PR45	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.999
A0A1I8NWN8	A0A1I8PS14	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8PUH6	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
A0A1I8NWN8	A0A1I8PXP9	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8PYP0	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8Q094	AAA domain-containing protein; Belongs to the AAA ATPase family.	VWFA domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8Q7G3	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
A0A1I8NWN8	A0A1I8Q7I4	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
A0A1I8NWN8	A0A1I8Q9L7	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8QC34	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
A0A1I8NWN8	A0A1I8QC76	AAA domain-containing protein; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
A0A1I8NWN8	A0A1I8QDQ4	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8QE54	AAA domain-containing protein; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.999
A0A1I8NWN8	A0A1I8QF75	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
A0A1I8NXP0	A0A1I8NWN8	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
A0A1I8NXP0	A0A1I8P7W1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	PCI domain-containing protein.	0.999