STRINGSTRING
AOB34247.1 AOB34247.1 AOB35393.1 AOB35393.1 sucC sucC sucD sucD leuC leuC leuD leuD leuB leuB ilvN ilvN ilvB ilvB AOB35800.1 AOB35800.1 AOB36221.1 AOB36221.1 AOB36456.1 AOB36456.1 ligK ligK AOB36923.1 AOB36923.1 AOB36924.1 AOB36924.1 AOB36925.1 AOB36925.1 AOB36930.1 AOB36930.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOB34247.1Hypothetical protein; Thiamine-pyrophosphate requiring enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
AOB35393.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (554 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (358 aa)
ilvNAcetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
AOB35800.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (565 aa)
AOB36221.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
AOB36456.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
ligK4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AOB36923.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the HpcH/HpaI aldolase family. (268 aa)
AOB36924.1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family. (395 aa)
AOB36925.1itaconyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AOB36930.13-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
Your Current Organism:
Bordetella holmesii
NCBI taxonomy Id: 35814
Other names: ATCC 51541, B. holmesii, CCUG 34073, CDC F5101, CDC nonoxidizer group 2 (NO-2), CIP 104394, DSM 13416, LMG 15945, LMG:15945, NCTC 12912
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