STRINGSTRING
gspE gspE BAV0367 BAV0367 BAV0403 BAV0403 htpG htpG mrp mrp engD engD actP actP mutL mutL BAV0912 BAV0912 ftsH ftsH mfd mfd smc smc BAV1206 BAV1206 paaD paaD uvrD uvrD BAV1429 BAV1429 clpX clpX lon lon uvrB uvrB hscA hscA cadA cadA fliI fliI BAV1790 BAV1790 recG recG clpA clpA lon-2 lon-2 BAV2360 BAV2360 clpB clpB BAV2531 BAV2531 BAV2545 BAV2545 BAV2692 BAV2692 kdpB kdpB BAV2711 BAV2711 mgtA mgtA ruvA ruvA ruvB ruvB minD minD BAV2793 BAV2793 BAV2808 BAV2808 rep rep BAV3245 BAV3245 uvrA uvrA hslU hslU BAV0271 BAV0271
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gspEGeneral secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (473 aa)
BAV0367Conserved hypothetical phage protein. (343 aa)
BAV0403Phage-related protein. (87 aa)
htpGChaperone protein HtpG; Molecular chaperone. Has ATPase activity. (630 aa)
mrpPutative amidase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa)
engDGTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
actPCopper-transporting P-type ATPase. (813 aa)
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (621 aa)
BAV0912Conserved hypothetical protein. (883 aa)
ftsHCell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (627 aa)
mfdTranscription-repair coupling factor; Start codon not provided. (1145 aa)
smcPutative chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1198 aa)
BAV1206Putative ATPase. (363 aa)
paaDPhenylacetic acid degradation protein; Start codon not provided. (166 aa)
uvrDDNA helicase II. (750 aa)
BAV1429Putative phage protein; Hypothetical gene not on same strand as others in the region. (87 aa)
clpXATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (432 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (810 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (676 aa)
hscAChaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (631 aa)
cadACadmium-transporting ATPase. (753 aa)
fliIFlagellum-specific ATP synthase; Start codon not provided. (479 aa)
BAV1790Putative cointegrate resolution protein. (354 aa)
recGATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (684 aa)
clpAATP-dependent clp protease ATP-binding (chaperone); Start codon not provided; Belongs to the ClpA/ClpB family. (767 aa)
lon-2ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (775 aa)
BAV2360Type IV pilus assembly protein. (504 aa)
clpBATP-dependent protease, ATPase subunit (chaperone); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (867 aa)
BAV2531Putative type IV pilus assembly protein (pseudogene); Unassigned protein domain. (443 aa)
BAV2545DNA helicase. (685 aa)
BAV2692Putative ATPase. (459 aa)
kdpBPotassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (711 aa)
BAV2711Putative ATPase. (288 aa)
mgtAMagnesium transporting ATPase, P-type 1; Also similar to BAV3245 (27.7 38d). (924 aa)
ruvAHolliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (190 aa)
ruvBHolliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (357 aa)
minDSeptum site-determining protein. (271 aa)
BAV2793ABC transporter, ATP-binding protein. (557 aa)
BAV2808Putative excinuclease ABC subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1900 aa)
repATP-dependent DNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (684 aa)
BAV3245Plasma membrane-type ATPase; Start codon not provided; Also similar to BAV2768 (27.7 38d). Seems to be more similar to eukaryotic plasma membrane ATPase. (881 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa)
hslUATP-dependent Hsl protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (444 aa)
BAV0271Putative ATPase with chaperone activity; Start codon not provided; Belongs to the ClpA/ClpB family. (872 aa)
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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