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| | BAV0791 | Conserved hypothetical protein; Belongs to the UPF0234 family. (160 aa) |
| | BAV0744 | Conserved hypothetical protein. (199 aa) |
| | mutL | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (621 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (275 aa) |
| | BAV0438 | Putative phage anti-repressor protein. (253 aa) |
| | BAV0415 | Phage-related protein. (123 aa) |
| | BAV0402 | Phage-related protein. (249 aa) |
| | traR | Putative nickase. (331 aa) |
| | BAV2215 | DNA-3-methyladenine glycosylase. (208 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (252 aa) |
| | BAV0137 | Conserved hypothetical protein; Belongs to the UPF0250 family. (90 aa) |
| | ssb | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (166 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa) |
| | recA | RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) |
| | lon-2 | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (775 aa) |
| | BAV2249 | Putative DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family. (230 aa) |
| | BAV2243 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. (90 aa) |
| | dnaE | DNA polymerase III alpha subunit; Similar to BAV2029 (30.755 38d.). (1163 aa) |
| | BAV2217 | Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.). (184 aa) |
| | BAV0268 | Conserved hypothetical protein. (134 aa) |
| | sodB | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (360 aa) |
| | dnaE2 | Putative DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1048 aa) |
| | BAV2028 | Conserved hypothetical protein. (432 aa) |
| | BAV1992 | ABC transporter, ATP-binding protein; Start codon not provided. (534 aa) |
| | fpr-2 | ferredoxin--NADP reductase. (258 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (684 aa) |
| | hslR | Ribosome-associated heat shock protein. (136 aa) |
| | BAV1851 | PadR-family transcriptional regulator. (167 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (904 aa) |
| | radA | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (435 aa) |
| | uvrC | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (577 aa) |
| | sodC | Superoxide dismutase [cu-zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (174 aa) |
| | alkA | DNA-3-methyladenine glycosylase. (214 aa) |
| | mutS | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (875 aa) |
| | hdeA | Putative membrane protein (pseudogene); Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Belongs to the HdeA family. (98 aa) |
| | trxB | Thioredoxin reductase. (317 aa) |
| | recN | DNA repair protein; May be involved in recombinational repair of damaged DNA. (550 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (181 aa) |
| | ruvA | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (190 aa) |
| | ruvB | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (357 aa) |
| | recQ | ATP-dependent DNA helicase. (606 aa) |
| | hdeB | Acid-resistance protein, (putative chaperone); Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Belongs to the HdeA family. (117 aa) |
| | BAV2808 | Putative excinuclease ABC subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1900 aa) |
| | tag | DNA-3-methyladenine glycosylase. (200 aa) |
| | BAV1810 | Conserved hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (537 aa) |
| | uup | ABC transporter, ATP-binding protein. (597 aa) |
| | BAV2898 | Putative exported protein. (247 aa) |
| | BAV2953 | Conserved hypothetical protein. (506 aa) |
| | BAV3038 | Putative NUDIX hydrolase; Belongs to the Nudix hydrolase family. (321 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa) |
| | ada | Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.). (358 aa) |
| | alkB | Alkylated DNA repair protein. (213 aa) |
| | ogt | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (185 aa) |
| | crc | Catabolite repression control protein. (260 aa) |
| | BAV3224 | Putative thioredoxin reductase. (295 aa) |
| | apaG | Conserved hypothetical protein. (124 aa) |
| | BAV3311 | BolA-like protein; Also similar to BAV1074 (37.6 38d); Belongs to the BolA/IbaG family. (81 aa) |
| | BAV3327 | Conserved hypothetical protein. (258 aa) |
| | BAV1636 | Putative mechanosensitive ion channel forming protein. (439 aa) |
| | xthA | Exodeoxyribonuclease III. (261 aa) |
| | BAV1629 | Conserved hypothetical protein. (168 aa) |
| | cho | Excinuclease; Start codon not provided. (301 aa) |
| | BAV1590 | Putative DNA photolyase; Start codon not provided. (538 aa) |
| | recJ | single-stranded-DNA-specific exonuclease; Start codon not provided. (568 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (676 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (213 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (810 aa) |
| | BAV1447 | Phage protein. (217 aa) |
| | BAV1428 | Putative antirepressor. (249 aa) |
| | BAV1418 | ABC transporter ATP-binding protein; Start codon not provided. (640 aa) |
| | BAV1405 | Putative membrane-bound metal-dependent hydrolase. (343 aa) |
| | BAV1370 | Putative radical SAM protein. (528 aa) |
| | BAV1360 | Putative exported protein. (129 aa) |
| | BAV1311 | Putative phage protein. (170 aa) |
| | BAV1307 | Putative phage endonuclease. (123 aa) |
| | BAV1242 | Putative exported protein. (140 aa) |
| | piuC | Putative iron-uptake factor (PkhD-type hydroxylase). (227 aa) |
| | recO | DNA repair protein; Involved in DNA repair and RecF pathway recombination. (195 aa) |
| | BAV1110 | Probable hydrolase. (218 aa) |
| | fpr | ferredoxin--NADP reductase. (263 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (695 aa) |
| | mfd | Transcription-repair coupling factor; Start codon not provided. (1145 aa) |
| | BAV1004 | Putative exported protein. (157 aa) |
| | recR | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa) |
| | BAV0913 | Putative nuclease/helicase; Belongs to the helicase family. UvrD subfamily. (1107 aa) |
| | BAV0912 | Conserved hypothetical protein. (883 aa) |
| | BAV0850 | Putative membrane protein. (105 aa) |
