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A0A1P8B2A8 A0A1P8B2A8 dl4425c dl4425c F4JML6_ARATH F4JML6_ARATH ETFQO ETFQO D2HGDH D2HGDH ACX2 ACX2 ACX1 ACX1 HMGCL HMGCL ACX3 ACX3 F3E22.17 F3E22.17 ALDH6B2 ALDH6B2 T11J7.4 T11J7.4 MCCA MCCA PED1 PED1 KAT5 KAT5 EFL4 EFL4 T8B10.170 T8B10.170 ECHIA ECHIA T11J7.5 T11J7.5 KAT1-2 KAT1-2 IBR3 IBR3 EFL3 EFL3 ECH2 ECH2 F4I10.70 F4I10.70 F23N20.17 F23N20.17 ACX4 ACX4 ETFA ETFA F23N20.16 F23N20.16 AACT1 AACT1 MCCB MCCB Q9LDF5_ARATH Q9LDF5_ARATH K23F3.9 K23F3.9 CHY1 CHY1 ACX3.2 ACX3.2 ETFB ETFB SDRA SDRA F12K11.12 F12K11.12 T13K14.90 T13K14.90 IVD IVD F19B15.150 F19B15.150 MFP2 MFP2 AIM1 AIM1 ACX1.2 ACX1.2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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gene co-occurrence
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A0A1P8B2A8Long chain acyl-CoA synthetase. (130 aa)
dl4425cProbable enoyl-CoA hydratase 2, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. (301 aa)
F4JML6_ARATHATP-dependent caseinolytic protease/crotonase family protein. (439 aa)
ETFQOElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. May act downstream of IVD and D2HGDH in the degradation of phytol or chlorophyll during dark-induced senescence and sugar starvation. Belongs to the ETF-QO/FixC family. (633 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase, mitochondrial; Catalyzes the oxidation of (R)-2-hydroxyglutarate to 2- oxoglutarate. May be involved in the catabolism of propionyl-CoA derived from beta-oxidation. Involved in degradation of lysine for the supply of carbon and electrons to the ETF/ETFQO complex during dark- induced sugar starvation; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (559 aa)
ACX2Acyl-coenzyme A oxidase 2, peroxisomal; Catalyzes the desaturation of long-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on substrates longer than C14 and mostly with C18-CoA. Activity on long-chain mono-unsaturated substrates is double than with the corresponding saturated substrates. (692 aa)
ACX1Peroxisomal acyl-coenzyme A oxidase 1; Catalyzes the desaturation of both long- and medium-chain acyl-CoAs to 2-trans-enoyl-CoAs. Most active with C14-CoA. Activity on long-chain mono-unsaturated substrates is 40% higher than with the corresponding saturated substrates. Seems to be an important factor in the general metabolism of root tips. May be involved in the biosynthesis of jasmonic acid. (664 aa)
HMGCLHydroxymethylglutaryl-CoA lyase, mitochondrial; Involved in the catabolism of branched amino acids such as leucine. (468 aa)
ACX3Acyl-coenzyme A oxidase 3, peroxisomal; Catalyzes the desaturation of medium-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on C8:0- to C14:0-CoA with a maximal activity on C12:0-CoA. (675 aa)
F3E22.17Putative acyl-coenzyme A oxidase At3g06690. (187 aa)
ALDH6B2Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (607 aa)
T11J7.4Probable 3-hydroxyisobutyryl-CoA hydrolase 2; Involved in valine catabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (378 aa)
MCCAMethylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. (734 aa)
PED13-ketoacyl-CoA thiolase 2, peroxisomal; Involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Confers sensitivity to 2,4-dichlorophenoxybutiric acid (2,4-DB). Required for local and systemic induction of jasmonic acid (JA) biosynthesis after wounding. Seems to be involved in JA biosynthesis during senescence. (462 aa)
KAT53-ketoacyl-CoA thiolase 5, peroxisomal; Probably involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Involved in systemic jasmonic acid (JA) biosynthesis after wounding and may be during senescence. (457 aa)
EFL4Protein ELF4-LIKE 4; Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. Belongs to the EARLY FLOWERING 4 family. (114 aa)
T8B10.1703-hydroxyisobutyryl-CoA hydrolase-like protein 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (401 aa)
ECHIAProbable enoyl-CoA hydratase 1, peroxisomal; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. (265 aa)
T11J7.5Probable 3-hydroxyisobutyryl-CoA hydrolase 3; Involved in valine catabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (378 aa)
KAT1-23-ketoacyl-CoA thiolase 1, peroxisomal; Involved in fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Implicated in jasmonic acid (JA) biosynthesis (By similarity). Belongs to the thiolase-like superfamily. Thiolase family. (443 aa)
IBR3Probable acyl-CoA dehydrogenase IBR3; Involved with IBR1 and IBR10 in the peroxisomal beta- oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin. May be responsible for catalyzing the first step in IBA-CoA beta-oxidation. May play a role in defense response to pathogenic bacteria. (824 aa)
EFL3Protein ELF4-LIKE 3; Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. (109 aa)
ECH2Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. (309 aa)
F4I10.70Haloacid dehalogenase-like hydrolase (HAD) superfamily protein. (353 aa)
F23N20.17Probable 3-hydroxyisobutyrate dehydrogenase-like 3, mitochondrial. (318 aa)
ACX4Acyl-coenzyme A oxidase 4, peroxisomal; Catalyzes the desaturation of short-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester). (436 aa)
ETFAElectron transfer flavoprotein subunit alpha, mitochondrial; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (ETF dehydrogenase). Involved in leucine catabolism and in phytol degradation (By similarity). (363 aa)
F23N20.16Probable 3-hydroxyisobutyrate dehydrogenase-like 2, mitochondrial. (299 aa)
AACT1Probable acetyl-CoA acetyltransferase, cytosolic 2; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
MCCBMethylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. (587 aa)
Q9LDF5_ARATH3-hydroxybutyryl-CoA dehydrogenase-like protein. (294 aa)
K23F3.9Thioesterase/thiol ester dehydrase-isomerase superfamily protein. (438 aa)
CHY13-hydroxyisobutyryl-CoA hydrolase 1; Involved in valine catabolism. May be indirectly involved in benzoic acid biosynthesis and in cold signaling and cold tolerance. Belongs to the enoyl-CoA hydratase/isomerase family. (378 aa)
ACX3.2Putative acyl-coenzyme A oxidase 3.2, peroxisomal; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (675 aa)
ETFBElectron transfer flavoprotein subunit beta, mitochondrial; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). Involved in leucine catabolism and in phytol degradation. (251 aa)
SDRAShort-chain dehydrogenase/reductase SDRA; Involved with IBR3 and IBR10 in the peroxisomal beta- oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin. May be responsible for catalyzing the dehydrogenation step in the conversion of IBA. May be involved in the peroxisomal activation of 2,4- dichlorophenoxybutyric acid (2,4-DB), a precursor of active auxins that inhibit root growth. (254 aa)
F12K11.123-hydroxyisobutyryl-CoA hydrolase-like protein 5; Belongs to the enoyl-CoA hydratase/isomerase family. (387 aa)
T13K14.90Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial. (347 aa)
IVDIsovaleryl-CoA dehydrogenase, mitochondrial; Involved in degradation of the branched-chain amino acids, phytol and lysine for the supply of carbon and electrons to the ETF/ETFQO complex during dark-induced sugar starvation. Belongs to the acyl-CoA dehydrogenase family. (409 aa)
F19B15.150Probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial. (334 aa)
MFP2Enoyl-CoA hydratase/3-2-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18). Possesses 3-hydroxy-3- phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA [...] (725 aa)
AIM1Enoyl-CoA hydratase/3-2-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in peroxisomal fatty acid beta-oxidation. Required for wound-induced jasmonate biosynthesis. Possesses enoyl-CoA hydratase activity against short chain substrates (C4-C6) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C16). Possesses cinnamoyl-CoA hydratase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of benzoylated glucosinolates (BGs) and substituted hydroxy [...] (721 aa)
ACX1.2Putative peroxisomal acyl-coenzyme A oxidase 1.2; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (664 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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