STRINGSTRING
IKU1 IKU1 MKS1 MKS1 WRKY33 WRKY33 VQ8 VQ8 SIB1 SIB1 WRKY10 WRKY10 VQ22 VQ22 VQ9 VQ9 VQ29 VQ29 SIB2 SIB2 CAMBP25 CAMBP25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IKU1Protein HAIKU1; Modulates seed size by negatively regulating the cellularization of syncytial endosperm. May function by binding and modulating the activity of WRKY10 transcription factor. (402 aa)
MKS1Protein MKS1; Regulator of plant defense response. May contribute to MPK4- regulated defense activation by coupling the kinase to specific WRKY transcription factors. (222 aa)
WRKY33Probable WRKY transcription factor 33; Transcription factor. Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. Involved in defense responses. Required for resistance to the necrotrophic fungal pathogen B.cinerea. Regulates the antagonistic relationship between defense pathways mediating responses to the bacterial pathogen P. syringae and the necrotrophic pathogen B.cinerea. Required for the phytoalexin camalexin synthesis following infection with B.cinerea. Acts as positive regulator of the camalexin biosynthetic ge [...] (519 aa)
VQ8VQ motif-containing protein 8, chloroplastic; May be involved in chloroplast development. (152 aa)
SIB1Sigma factor binding protein 1, chloroplastic; Contributes to plant defense. May regulate chloroplast metabolism upon infection with pathogens such as Pseudomonas syringae. Functions as activator of WRKY33 in plant defense against necrotrophic pathogens by stimulating the DNA-binding activity of WRKY33. (151 aa)
WRKY10Probable WRKY transcription factor 10; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Modulates seed size by negatively regulating the cellularization of syncytial endosperm. (485 aa)
VQ22VQ motif-containing protein 22; May function as positive regulator of plant growth. (192 aa)
VQ9VQ motif-containing protein 9; Functions as a negative regulator of salt stress response. Functions as repressor of WRKY8 transcription factor by decreasing the DNA-binding activity of WRKY8 and acts antagonistically with WRKY8 to regulate sodium and potassium homeostasis under salt stress. (311 aa)
VQ29VQ motif-containing protein 29; May function as negative regulator of flowering transition. (123 aa)
SIB2Sigma factor binding protein 2, chloroplastic; Functions as activator of WRKY33 in plant defense against necrotrophic pathogens by stimulating the DNA-binding activity of WRKY33. (141 aa)
CAMBP25Calmodulin-binding protein 25; Calmodulin-binding protein that functions as a negative regulator of osmotic stress tolerance. (238 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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