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sucC sucC sucD sucD mqo mqo SFR41203.1 SFR41203.1 SFR45620.1 SFR45620.1 SFR45628.1 SFR45628.1 mqo-2 mqo-2 fumC fumC SFR46611.1 SFR46611.1 SFR47435.1 SFR47435.1 SFR47663.1 SFR47663.1 pckA pckA SFR48784.1 SFR48784.1 SFR49489.1 SFR49489.1 SFR55763.1 SFR55763.1 SFR58206.1 SFR58206.1 SFR38412.1 SFR38412.1 SFR38416.1 SFR38416.1 SFR38423.1 SFR38423.1 SFR38426.1 SFR38426.1 SFR38432.1 SFR38432.1 SFR38436.1 SFR38436.1 SFR38443.1 SFR38443.1 SFR38447.1 SFR38447.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
mqoMalate dehydrogenase (quinone). (484 aa)
SFR41203.1Aconitase; Belongs to the aconitase/IPM isomerase family. (869 aa)
SFR45620.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (562 aa)
SFR45628.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
mqo-2Malate dehydrogenase (quinone). (492 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
SFR46611.1Dihydrolipoamide dehydrogenase. (480 aa)
SFR47435.1Pyruvate-ferredoxin/flavodoxin oxidoreductase. (1197 aa)
SFR47663.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (920 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (511 aa)
SFR48784.1Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (747 aa)
SFR49489.1Pyruvate carboxylase subunit B. (599 aa)
SFR55763.1Antitoxin CptB. (90 aa)
SFR58206.1Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (504 aa)
SFR38412.1Citrate synthase; Belongs to the citrate synthase family. (424 aa)
SFR38416.1Succinate dehydrogenase subunit C. (124 aa)
SFR38423.1Succinate dehydrogenase / fumarate reductase membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa)
SFR38426.1Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
SFR38432.1Succinate dehydrogenase subunit B. (234 aa)
SFR38436.12-oxoglutarate dehydrogenase E1 component. (944 aa)
SFR38443.12-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa)
SFR38447.1Dihydrolipoamide dehydrogenase. (480 aa)
Your Current Organism:
Marinobacter gudaonensis
NCBI taxonomy Id: 375760
Other names: CGMCC 1.6294, DSM 18066, LMG 23509, LMG:23509, M. gudaonensis, Marinobacter gudaonensis Gu et al. 2007, Marinobacter sp. 61A, Marinobacter sp. 61B, strain SL014B61A
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