STRINGSTRING
purU purU ppc ppc AMM31285.1 AMM31285.1 pckG pckG AMM31330.1 AMM31330.1 AMM31366.1 AMM31366.1 AMM31674.1 AMM31674.1 purU-4 purU-4 fumC fumC AMM32462.1 AMM32462.1 mqo mqo mdh mdh AMM33995.1 AMM33995.1 purU-5 purU-5 AMM34280.1 AMM34280.1 AMM34424.1 AMM34424.1 AMM34426.1 AMM34426.1 AMM34427.1 AMM34427.1 AMM34515.1 AMM34515.1 AMM34516.1 AMM34516.1 glcB glcB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (301 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (957 aa)
AMM31285.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (813 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa)
AMM31330.1Pyruvate dehydrogenase; Pfam:pfam02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family. (574 aa)
AMM31366.1Thiamine pyrophosphate-binding protein; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Belongs to the TPP enzyme family. (596 aa)
AMM31674.1Pfam:pfam01070 FMN-dependent dehydrogenase. (428 aa)
purU-4Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (477 aa)
AMM32462.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1133 aa)
mqoPfam:pfam06039 Malate:quinone oxidoreductase (Mqo). (496 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AMM33995.1Malate dehydrogenase; Pfam:pfam03949 Malic enzyme, NAD binding domain. (460 aa)
purU-5Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (303 aa)
AMM34280.1Malate dehydrogenase (Oxaloacetate decarboxylating); Pfam:pfam03949 Malic enzyme, NAD binding domain. (398 aa)
AMM34424.1Pfam:pfam02436 Conserved carboxylase domain. (496 aa)
AMM34426.1Hypothetical protein; Pfam:pfam00391 PEP-utilizing enzyme, mobile domain. (629 aa)
AMM34427.1Hypothetical protein; Pfam:pfam01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (364 aa)
AMM34515.1Phosphoenolpyruvate synthase; Pfam:pfam01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (324 aa)
AMM34516.1Hypothetical protein; Pfam:pfam00391 PEP-utilizing enzyme, mobile domain. (636 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (728 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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