52 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PROC	Protein C, inactivator of coagulation factors Va and VIIIa. (487 aa)
	ENSPCOP00000031789	Uncharacterized protein. (227 aa)
	HPSE	Heparanase. (395 aa)
	F11	Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
	SH2B3	SH2B adaptor protein 3. (539 aa)
	HRG	Histidine rich glycoprotein. (468 aa)
	FAP	Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S type. (663 aa)
	PLAU	Plasminogen activator, urokinase. (432 aa)
	SERPINC1	Serpin family C member 1; Belongs to the serpin family. (465 aa)
	GP1BA	Glycoprotein Ib platelet subunit alpha. (598 aa)
	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif 18. (1115 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
	PROS1	Protein S. (675 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	PDGFA	Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
	THBS1	Thrombospondin 1. (1185 aa)
	F3	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (294 aa)
	FGA	Fib_alpha domain-containing protein. (649 aa)
	EMILIN1	Elastin microfibril interfacer 1. (1022 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (409 aa)
	EMILIN2	Elastin microfibril interfacer 2. (1061 aa)
	SERPING1	Serpin family G member 1; Belongs to the serpin family. (491 aa)
	SERPINB2	Serpin family B member 2; Belongs to the serpin family. (417 aa)
	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (337 aa)
	CEACAM1	Uncharacterized protein. (523 aa)
	DMTN	Dematin actin binding protein. (412 aa)
	ENPP4	Ectonucleotide pyrophosphatase/phosphodiesterase 4. (403 aa)
	FGG	Fibrinogen gamma chain. (456 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
	CD9	Tetraspanin. (228 aa)
	ANO6	Anoctamin. (932 aa)
	UBASH3B	Ubiquitin associated and SH3 domain containing B. (649 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	SERPINE1	Serpin family E member 1; Belongs to the serpin family. (402 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	F12	Coagulation factor XII. (605 aa)
	APOE	Apolipoprotein E. (314 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	TBXA2R	Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
	C1QTNF6	C1q and TNF related 6. (263 aa)
	FGB	Fibrinogen beta chain. (492 aa)
	C1QTNF1	C1q and TNF related 1. (281 aa)
	KNG1	Uncharacterized protein. (391 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (237 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (606 aa)
	USF1	Upstream transcription factor 1. (310 aa)
	PRKG1	Protein kinase cGMP-dependent 1. (593 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (487 aa)
	EPHB2	EPH receptor B2. (1039 aa)
	FOXA2	Forkhead box A2. (463 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABAT	PRKG1	ENSPCOP00000012228	ENSPCOP00000001140	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Protein kinase cGMP-dependent 1.	0.521
ADAMTS18	THBS1	ENSPCOP00000026530	ENSPCOP00000024785	ADAM metallopeptidase with thrombospondin type 1 motif 18.	Thrombospondin 1.	0.414
ALOX12	F12	ENSPCOP00000027488	ENSPCOP00000010528	Arachidonate 12-lipoxygenase, 12S type.	Coagulation factor XII.	0.429
APOE	CAV1	ENSPCOP00000010240	ENSPCOP00000025045	Apolipoprotein E.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.414
APOE	CD36	ENSPCOP00000010240	ENSPCOP00000010616	Apolipoprotein E.	CD36 molecule; Belongs to the CD36 family.	0.447
APOE	NOS3	ENSPCOP00000010240	ENSPCOP00000009840	Apolipoprotein E.	Nitric oxide synthase 3.	0.467
C1QTNF6	EMILIN2	ENSPCOP00000008367	ENSPCOP00000022603	C1q and TNF related 6.	Elastin microfibril interfacer 2.	0.416
CAV1	APOE	ENSPCOP00000025045	ENSPCOP00000010240	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein E.	0.414
CAV1	CD36	ENSPCOP00000025045	ENSPCOP00000010616	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	CD36 molecule; Belongs to the CD36 family.	0.452
CAV1	CD9	ENSPCOP00000025045	ENSPCOP00000013223	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tetraspanin.	0.410
CAV1	NOS3	ENSPCOP00000025045	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.940
CD36	APOE	ENSPCOP00000010616	ENSPCOP00000010240	CD36 molecule; Belongs to the CD36 family.	Apolipoprotein E.	0.447
CD36	CAV1	ENSPCOP00000010616	ENSPCOP00000025045	CD36 molecule; Belongs to the CD36 family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.452
CD36	CD9	ENSPCOP00000010616	ENSPCOP00000013223	CD36 molecule; Belongs to the CD36 family.	Tetraspanin.	0.813
CD36	ENSPCOP00000031789	ENSPCOP00000010616	ENSPCOP00000031789	CD36 molecule; Belongs to the CD36 family.	Uncharacterized protein.	0.433
CD36	THBS1	ENSPCOP00000010616	ENSPCOP00000024785	CD36 molecule; Belongs to the CD36 family.	Thrombospondin 1.	0.950
CD9	CAV1	ENSPCOP00000013223	ENSPCOP00000025045	Tetraspanin.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.410
CD9	CD36	ENSPCOP00000013223	ENSPCOP00000010616	Tetraspanin.	CD36 molecule; Belongs to the CD36 family.	0.813
CD9	ENSPCOP00000031789	ENSPCOP00000013223	ENSPCOP00000031789	Tetraspanin.	Uncharacterized protein.	0.434
CD9	F11	ENSPCOP00000013223	ENSPCOP00000029754	Tetraspanin.	Coagulation factor XI; Belongs to the peptidase S1 family.	0.405