STRINGSTRING
PAG1 PAG1 EPGN EPGN PIK3CA PIK3CA EGF EGF PXN PXN FNDC3A FNDC3A TGFA TGFA HBEGF HBEGF PIK3R1 PIK3R1 SRC SRC BTC BTC FNDC3B FNDC3B EREG EREG GRB2 GRB2 PTPN11 PTPN11 TGFB1I1 TGFB1I1 CSK CSK EGFR EGFR AREG AREG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (426 aa)
EPGNEpithelial mitogen. (153 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
EGFEpidermal growth factor. (1132 aa)
PXNPaxillin. (1073 aa)
FNDC3AFibronectin type III domain containing 3A. (1044 aa)
TGFATransforming growth factor alpha. (190 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SRCTyrosine-protein kinase. (543 aa)
BTCBetacellulin. (140 aa)
FNDC3BFibronectin type III domain containing 3B. (1156 aa)
EREGEpiregulin. (166 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
CSKTyrosine-protein kinase. (450 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
AREGAmphiregulin. (253 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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