STRINGSTRING
TRIB3 TRIB3 MTOR MTOR PDPK1 PDPK1 STX12 STX12 PAK1 PAK1 VAV2 VAV2 NOS3 NOS3 JUP JUP VAV1 VAV1 MLST8 MLST8 LOC105812452 LOC105812452 ENSPCOP00000018566 ENSPCOP00000018566 AKT2 AKT2 CDH5 CDH5 ARVCF ARVCF VAV3 VAV3 CTNND1 CTNND1 PAK2 PAK2 MAPKAP1 MAPKAP1 HSP90AA1 HSP90AA1 CTNNA1 CTNNA1 RICTOR RICTOR THEM4 THEM4 AKT1 AKT1 AKT3 AKT3 STX7 STX7 CAV1 CAV1 PAK3 PAK3 CTNNB1 CTNNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIB3Tribbles pseudokinase 3. (367 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
VAV2Vav guanine nucleotide exchange factor 2. (771 aa)
NOS3Nitric oxide synthase 3. (994 aa)
JUPJunction plakoglobin. (745 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
LOC105812452HATPase_c domain-containing protein. (680 aa)
ENSPCOP00000018566Uncharacterized protein. (113 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
ARVCFARVCF delta catenin family member. (965 aa)
VAV3Vav guanine nucleotide exchange factor 3. (765 aa)
CTNND1Catenin delta 1. (984 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
MAPKAP1MAPK associated protein 1. (492 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (816 aa)
CTNNA1Catenin alpha 1. (906 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1646 aa)
THEM4Thioesterase superfamily member 4. (202 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
STX7Syntaxin 7. (173 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
CTNNB1Catenin beta 1. (781 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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