STRINGSTRING
OPRD1 OPRD1 OPRM1 OPRM1 EP300 EP300 JUN JUN IMPDH1 IMPDH1 CD8A CD8A RXRA RXRA DRD2 DRD2 NQO1 NQO1 TOP2A TOP2A DRD3 DRD3 AGTR2 AGTR2 PPARG PPARG PTGS2 PTGS2 ACTB ACTB OPRK1 OPRK1 PXDN PXDN MTOR MTOR PRKCB PRKCB ESR1 ESR1 CSF3 CSF3 NR3C1 NR3C1 LOC102376607 LOC102376607 PPP2CA PPP2CA PRKCA PRKCA IMPDH2 IMPDH2 CD4 CD4 PTGER3 PTGER3 PXDNL PXDNL AGTR1 AGTR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OPRD1Delta-type opioid receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (301 aa)
OPRM1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (300 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (282 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (445 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain. (223 aa)
RXRARetinoic acid receptor RXR-alpha isoform X2. (486 aa)
DRD2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
NQO1NAD(P)H dehydrogenase [quinone] 1. (345 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1488 aa)
DRD3D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (423 aa)
AGTR2Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (369 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
PTGS2Prostaglandin G/H synthase 2. (605 aa)
ACTBActin, cytoplasmic 1. (375 aa)
OPRK1Kappa-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (381 aa)
PXDNPeroxidasin homolog. (1453 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
PRKCBNon-specific serine/threonine protein kinase. (544 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
CSF3LOW QUALITY PROTEIN: granulocyte colony-stimulating factor. (235 aa)
NR3C1Glucocorticoid receptor isoform X1. (807 aa)
LOC102376607Peroxidasin-like isoform X1. (1406 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
PRKCANon-specific serine/threonine protein kinase. (552 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase 2. (417 aa)
CD4T-cell surface glycoprotein CD4. (491 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype. (149 aa)
PXDNLPeroxidasin-like protein. (1468 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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