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NIS_0032 NIS_0032 NIS_0034 NIS_0034 NIS_0035 NIS_0035 pckA pckA NIS_0056 NIS_0056 dapF dapF NIS_0128 NIS_0128 NIS_0258 NIS_0258 NIS_0293 NIS_0293 accA accA rpe rpe glcD glcD hemB hemB NIS_0367 NIS_0367 tal tal lysA lysA NIS_0416 NIS_0416 thrB thrB prsA prsA asd asd NIS_0498 NIS_0498 acs acs fbaA fbaA NIS_0571 NIS_0571 NIS_0593 NIS_0593 NIS_0652 NIS_0652 NIS_0653 NIS_0653 NIS_0664 NIS_0664 NIS_0688 NIS_0688 NIS_0689 NIS_0689 NIS_0690 NIS_0690 dapA dapA rpiB rpiB folD folD hemL hemL fbp fbp gltX1 gltX1 NIS_0816 NIS_0816 ubiX ubiX acnB acnB NIS_0834 NIS_0834 mdh mdh NIS_0836 NIS_0836 NIS_0837 NIS_0837 sucC sucC sucD sucD NIS_0841 NIS_0841 NIS_0842 NIS_0842 NIS_0843 NIS_0843 NIS_0844 NIS_0844 pfkA pfkA gpmA gpmA NIS_0921 NIS_0921 ppsA ppsA NIS_0924 NIS_0924 NIS_0927 NIS_0927 NIS_0931 NIS_0931 NIS_0932 NIS_0932 NIS_0933 NIS_0933 NIS_0934 NIS_0934 pgi pgi pgm pgm NIS_0952 NIS_0952 NIS_0961 NIS_0961 NIS_0962 NIS_0962 NIS_1007 NIS_1007 hemC hemC hemA hemA thrC thrC argD argD NIS_1140 NIS_1140 NIS_1152 NIS_1152 glyA glyA accD accD gltD gltD gltB gltB dapE dapE NIS_1302 NIS_1302 NIS_1303 NIS_1303 NIS_1308 NIS_1308 NIS_1338 NIS_1338 NIS_1428 NIS_1428 NIS_1434 NIS_1434 NIS_1436 NIS_1436 cysK cysK tpiA tpiA pgk pgk NIS_1492 NIS_1492 glnA glnA dapB dapB fdhF fdhF NIS_1553 NIS_1553 NIS_1602 NIS_1602 NIS_1603 NIS_1603 NIS_1604 NIS_1604 NIS_1605 NIS_1605 NIS_1634 NIS_1634 NIS_1640 NIS_1640 gltX gltX dapD dapD accC accC accB accB eno eno NIS_1773 NIS_1773 NIS_1777 NIS_1777 NIS_1789 NIS_1789 NIS_1790 NIS_1790 NIS_1794 NIS_1794 NIS_1795 NIS_1795 NIS_1796 NIS_1796 NIS_1805 NIS_1805 napA napA NIS_1820 NIS_1820 NIS_1828 NIS_1828 NIS_1829 NIS_1829 NIS_1830 NIS_1830 NIS_1831 NIS_1831 NIS_1832 NIS_1832
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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NIS_0032Sulfur oxidation protein, flavocytochrome c. (448 aa)
NIS_0034Sulfur oxidation protein SoxY. (156 aa)
NIS_0035Sulfur oxidation protein SoxZ. (114 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (525 aa)
NIS_0056D-isomer specific 2-hydroxyacid dehydrogenase, catalytic component. (314 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (250 aa)
NIS_0128D-isomer specific 2-hydroxyacid dehydrogenase, catalytic component. (309 aa)
NIS_0258Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (646 aa)
NIS_0293FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (680 aa)
accAacetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (212 aa)
glcDGlycolate oxidase, subunit GlcD. (460 aa)
hemBPorphobilinogen synthase; Belongs to the ALAD family. (321 aa)
NIS_0367Anaerobic glycerol-3-phosphate dehydrogenase subunit C. (424 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (326 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (400 aa)
NIS_0416Phosphoesterase. (312 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
NIS_0498Diaminopimelate decarboxylase. (443 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
NIS_05714Fe-4S ferredoxin. (214 aa)
NIS_0593Sulfate adenylyltransferase. (396 aa)
NIS_0652ATP citrate synthase, subunit 1; Similar to N terminus of ATP-citrate synthase (ATP-citrate (pro-S-)-lyase). (443 aa)
NIS_0653ATP citrate synthase, subunit 2; Similar to C terminus of ATP-citrate synthase (ATP-citrate (pro-S-)-lyase). (614 aa)
NIS_0664D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
NIS_0688Succinate dehydrogenase/fumarate reductase, subunit C. (292 aa)
NIS_0689Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. (318 aa)
NIS_0690Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (571 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
rpiBRibose 5-phosphate isomerase B. (146 aa)
folD5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (427 aa)
fbpFructose-1,6-bisphosphatase. (279 aa)
gltX1glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (431 aa)
NIS_0816Serine O-acetyltransferase. (238 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (174 aa)
acnBAconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (859 aa)
NIS_0834Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (738 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (318 aa)
NIS_0836Fumarate/tartrate hydratase, alpha subunit; EC 4.2.1.32/EC 4.2.1.2, FumA/TtdA. (287 aa)
NIS_0837Fumarate/tartrate hydratase, beta subunit; EC 4.2.1.32/EC 4.2.1.2, FumB/TtdB. (184 aa)
sucCsuccinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa)
sucDsuccinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
NIS_08412-oxoglutarate ferredoxin oxidoreductase, delta subunit; 2-oxoglutarate synthase component. (112 aa)
NIS_08422-oxoglutarate ferredoxin oxidoreductase, alpha subunit; 2-oxoglutarate synthase component. (382 aa)
NIS_08432-oxoglutarate ferredoxin oxidoreductase, beta subunit; 2-oxoglutarate synthase component. (284 aa)
NIS_08442-oxoglutarate ferredoxin oxidoreductase, gamma subunit; 2-oxoglutarate synthase component. (204 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (317 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (230 aa)
NIS_0921Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (799 aa)
NIS_0924Conserved hypothetical protein. (636 aa)
NIS_0927Fructose-bisphosphate aldolase, class I. (302 aa)
NIS_0931Pyruvate/2-oxoglutarate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase. (439 aa)
NIS_0932Pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; EC 2.3.1.12/EC 2.3.1.61, AceF/SucB OdhB. (408 aa)
NIS_0933Pyruvate/2-oxoglutarate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
NIS_0934Pyruvate/2-oxoglutarate dehydrogenase complex, E1 component, alpha subunit; EC 1.2.4.1/EC 1.2.4.2, PdhA/AceE/SucA OdhA. (323 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (413 aa)
pgmPhosphoglucomutase, alpha-D-glucose phosphate-specific. (529 aa)
NIS_0952Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (521 aa)
NIS_0961Ni-Fe hydrogenase, small subunit HupS. (286 aa)
NIS_0962Ni-Fe hydrogenase, large subunit HupV. (403 aa)
NIS_1007Conserved hypothetical protein. (267 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (432 aa)
thrCThreonine synthase. (490 aa)
argDAcetylornithine/succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
NIS_1140Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. (402 aa)
NIS_1152Thiosulfate sulfurtransferase. (286 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
accDacetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (285 aa)
gltDGlutamate synthase (NADPH), small chain. (459 aa)
gltBGlutamate synthase (NADPH), large chain. (1474 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (364 aa)
NIS_1302Na+-transporting oxaloacetate decarboxylase, beta subunit. (439 aa)
NIS_1303Na+-transporting oxaloacetate decarboxylase, alpha subunit. (599 aa)
NIS_1308Phosphoserine phosphatase. (207 aa)
NIS_1338uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (213 aa)
NIS_1428Phosphomannomutase. (457 aa)
NIS_1434Molybdopterin oxidoreductase, iron sulfur subunit. (519 aa)
NIS_1436Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (632 aa)
cysKCysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (293 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (232 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
NIS_1492Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
glnAGlutamine synthase. (481 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (254 aa)
fdhFFormate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (680 aa)
NIS_1553Homoserine dehydrogenase. (420 aa)
NIS_1602Pyruvate:ferredoxin oxidoreductase, beta subunit; Pyruvate synthase component. (332 aa)
NIS_1603Pyruvate:ferredoxin oxidoreductase, alpha subunit; Pyruvate synthase component. (405 aa)
NIS_1604Pyruvate:ferredoxin oxidoreductase, delta subunit; Pyruvate synthase component. (143 aa)
NIS_1605Pyruvate:ferredoxin oxidoreductase, gamma subunit; Pyruvate synthase component. (185 aa)
NIS_1634Conserved hypothetical protein; Similar to C terminus of NAD-glutamate dehydrogenase. (1006 aa)
NIS_1640Malate oxidoreductase. (417 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (462 aa)
dapDTetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (393 aa)
accCacetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (421 aa)
NIS_1773Pyruvate kinase; Belongs to the pyruvate kinase family. (458 aa)
NIS_1777Conserved hypothetical protein. (191 aa)
NIS_1789Nitrous-oxide reductase NosZ. (867 aa)
NIS_1790uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (243 aa)
NIS_1794Nitrite reductase (NO-forming). (552 aa)
NIS_1795Nitric oxide reductase, cytochrome b subunit; Belongs to the heme-copper respiratory oxidase family. (486 aa)
NIS_1796Nitric-oxide reductase, small subunit, C terminal, cytochrome c subunit. (225 aa)
NIS_1805Periplasmic nitrate reductase, small subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (193 aa)
napAPeriplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (936 aa)
NIS_1820Uncharacterized protein; Probable gene remnant. Similar to the N-terminal region of Rhodovulum sulfidophilum SH1 dimethylsulfide dehydrogenase alpha subunit precursor DdhA (910 aa). (375 aa)
NIS_1828Sulfur oxidation protein SoxB; Belongs to the 5'-nucleotidase family. (587 aa)
NIS_1829Conserved hypothetical protein; Similar to sulfur oxidation protein SoxA, cytochrome c. (256 aa)
NIS_1830Conserved hypothetical protein; Similar to sulfur oxidation protein SoxZ. (111 aa)
NIS_1831Sulfur oxidation protein SoxY. (156 aa)
NIS_1832Sulfur oxidation protein SoxX. (183 aa)
Your Current Organism:
Nitratiruptor sp. SB1552
NCBI taxonomy Id: 387092
Other names: N. sp. SB155-2, Nitratiruptor sp. SB155-2
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