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| | aroE-1 | Shikimate 5-dehydrogenase 1; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Protein involved in catalytic activity and metabolic process; Belongs to the TrpF family. (222 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (301 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (107 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (262 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Protein involved in catalytic activity and metabolic process. (248 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa) |
| | hisB | Protein involved in imidazoleglycerol-phosphate dehydratase activity and histidine biosynthetic process. (202 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa) |
| | ANL57513.1 | Ornithine cyclodeaminase protein; Protein involved in nucleotide binding. (315 aa) |
| | speF | Ornithine decarboxylase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process. (787 aa) |
| | ANL57572.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) |
| | arcA | Protein involved in arginine deiminase activity and arginine catabolic process. (409 aa) |
| | fabI-1 | Enoyl-(acyl carrier protein) reductase 1; Protein involved in nucleotide binding. (268 aa) |
| | ANL57613.1 | Protein involved in prephenate dehydratase activity and L-phenylalanine biosynthetic process. (284 aa) |
| | gyaR-1 | Glyoxylate reductase 1; Protein involved in nucleotide binding, NAD binding, metabolic process and oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa) |
| | gpmA-1 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (211 aa) |
| | glk | Glucokinase; Protein involved in glucokinase activity, ATP binding, glycolysis and glucose 6-phosphate metabolic process; Belongs to the bacterial glucokinase family. (341 aa) |
| | ghrA-1 | Bifunctional glyoxylate/hydroxypyruvate reductase A 1; Protein involved in nucleotide binding, cofactor binding and oxidation-reduction process. (319 aa) |
| | deoD | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (266 aa) |
| | ANL57790.1 | Protein involved in rRNA (adenine-N6,N6-)-dimethyltransferase activity, rRNA methyltransferase activity and rRNA modification. (199 aa) |
| | cysK | Protein involved in cysteine synthase activity, pyridoxal phosphate binding and cysteine biosynthetic process from serine. (320 aa) |
| | ubiE | Bifunctional 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase/demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (258 aa) |
| | fadB | enoyl-CoA hydratase; Protein involved in catalytic activity and metabolic process; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | metK | S-adenosylmethionine synthetase; Protein involved in methionine adenosyltransferase activity, ATP binding and S-adenosylmethionine biosynthetic process; Belongs to the AdoMet synthase family. (417 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa) |
| | frk | Fructokinase; Protein involved in phosphotransferase activity, alcohol group as acceptor. (308 aa) |
| | otsA | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (468 aa) |
| | pgi | Protein involved in glucose-6-phosphate isomerase activity, gluconeogenesis and glycolysis; Belongs to the GPI family. (541 aa) |
| | ANL57966.1 | Aldo/keto reductase protein. (339 aa) |
| | argD | Acetylornithine aminotransferase; Protein involved in catalytic activity, pyridoxal phosphate binding and arginine metabolic process; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (304 aa) |
| | fadA | acetyl-CoA C-acetyltransferase; Protein involved in transferase activity, transferring acyl groups other than amino-acyl groups and metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | fadJ | Fatty acid oxidation complex subunit alpha FadJ; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process. (738 aa) |
| | ANL58040.1 | 3-hydroxyisobutyryl-CoA hydrolase; Protein involved in catalytic activity and metabolic process. (350 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa) |
| | ANL58075.1 | Dihydrodipicolinate synthetase-like protein; Protein involved in catalytic activity and metabolic process; Belongs to the DapA family. (305 aa) |
| | aglA | Alpha-glucosidase; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process. (550 aa) |
| | zwf-1 | Glucose-6-phosphate 1-dehydrogenase 1; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | aceA | Isocitrate lyase; Protein involved in catalytic activity and carboxylic acid metabolic process. (429 aa) |
| | ANL58222.1 | Protein involved in nucleotidyltransferase activity and biosynthetic process. (237 aa) |
| | guaB | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | glcD | Glycolate oxidase subunit GlcD; Protein involved in catalytic activity, oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. (479 aa) |
| | glcE | Glycolate oxidase FAD-binding subunit GlcE; Protein involved in catalytic activity, oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. (400 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit GlcF; Protein involved in oxidoreductase activity, iron-sulfur cluster binding and oxidation-reduction process. (436 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (373 aa) |
| | hisG | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (231 aa) |
| | ribF | Bifunctional riboflavin kinase/FMN adenylyltransferase; Protein involved in riboflavin kinase activity and riboflavin biosynthetic process; Belongs to the ribF family. (327 aa) |
| | ANL58328.1 | Protein involved in phosphatidylinositol phosphorylation. (285 aa) |
| | ANL58331.1 | Protein involved in phosphoglycolate phosphatase activity and metabolic process. (240 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (302 aa) |
| | ispB | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (338 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | purD | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. (423 aa) |
| | ubiA | UbiA prenyltransferase family protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (340 aa) |
| | ANL58392.1 | acyl-CoA dehydrogenase protein; Protein involved in oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, metabolic process and oxidation-reduction process. (591 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa) |
| | ribBA-1 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II RibBA 1; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (367 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (454 aa) |
| | fabI-2 | Enoyl-(acyl carrier protein) reductase 2; Protein involved in nucleotide binding, fatty acid biosynthetic process and oxidation-reduction process. (272 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (316 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (333 aa) |
| | thrB | Homoserine kinase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | thrC | Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process. (471 aa) |
| | ppdK | Pyruvate phosphate dikinase; Protein involved in catalytic activity, ligase activity and phosphorylation; Belongs to the PEP-utilizing enzyme family. (894 aa) |
| | ANL58583.1 | Protein involved in oxidoreductase activity and metabolic process. (248 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (498 aa) |
| | cysD | Protein involved in sulfate adenylyltransferase (ATP) activity and sulfate reduction. (317 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase 2; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa) |
| | ANL58689.1 | Aminotransferase class 4 protein; Protein involved in catalytic activity and metabolic process. (295 aa) |
| | ANL58701.1 | Phosphatidylethanolamine N-methyltransferase protein; Protein involved in methyltransferase activity and metabolic process. (217 aa) |
| | gcd | Quinoprotein glucose dehydrogenase; Protein involved in oxidoreductase activity, acting on CH-OH group of donors, quinone binding and oxidation-reduction process. (779 aa) |
| | ANL58806.1 | Short-chain dehydrogenase protein; Protein involved in nucleotide binding. (262 aa) |
| | ANL58832.1 | Histidinol-phosphate aminotransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process. (370 aa) |
| | dapA-1 | Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | pssA | Protein involved in CDP-diacylglycerol-serine O-phosphatidyltransferase activity, phospholipid biosynthetic process and CDP-diacylglycerol metabolic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (281 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa) |
| | ANL58892.1 | 2-isopropylmalate/homocitrate synthase family transferase protein; Protein involved in catalytic activity and leucine biosynthetic process; Belongs to the alpha-IPM synthase/homocitrate synthase family. (537 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (496 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase; Protein involved in catalytic activity, binding and metabolic process. (314 aa) |
| | nodG | 3-oxoacyl-(acyl-carrier-protein) reductase nodulation protein NodG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | acpP | Acyl carrier protein AcpP; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Protein involved in catalytic activity and 'de novo' IMP biosynthetic process. (357 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Protein involved in catalytic activity, metal ion binding and tetrapyrrole biosynthetic process; Belongs to the ALAD family. (337 aa) |
| | glyA-1 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (432 aa) |
| | ribE | Riboflavin synthase subunit alpha; Protein involved in oxidoreductase activity and oxidation-reduction process. (203 aa) |
| | rmlA-2 | Glucose-1-phosphate thymidylyltransferase 2; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (295 aa) |
| | rfbB-2 | dTDP-glucose-4,6-dehydratase 2; Protein involved in nucleotide binding, coenzyme binding and nucleotide-sugar metabolic process; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (351 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (192 aa) |
| | ribH-1 | 6,7-dimethyl-8-ribityllumazine synthase 1; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (151 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa) |
| | ANL59017.1 | SAM-dependent methyltransferase protein. (210 aa) |
| | ctaA | Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (367 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (310 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (206 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | ilvD-1 | Dihydroxy-acid dehydratase 1; Protein involved in catalytic activity and metabolic process; Belongs to the IlvD/Edd family. (612 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (164 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (404 aa) |
| | cysB | Cysteine synthase; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. (345 aa) |
| | ttuD | Hydroxypyruvate reductase. (422 aa) |
| | surE-1 | 5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (257 aa) |
| | ANL59310.1 | Phytoene synthase protein; Protein involved in transferase activity and biosynthetic process. (285 aa) |
| | accC-1 | acetyl-CoA carboxylase biotin carboxylase subunit AccC 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | accB-1 | acetyl-CoA carboxylase biotin carboxyl carrier subunit AccB 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | hom-1 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. (441 aa) |
| | metC | Cystathionine beta-lyase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process. (396 aa) |
| | cysE-1 | Serine O-acetyltransferase 1; Protein involved in transferase activity and cysteine biosynthetic process from serine. (277 aa) |
| | uppS | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (247 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the CDS family. (276 aa) |
| | gltA | Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process; Belongs to the citrate synthase family. (429 aa) |
| | eno-1 | Enolase 1; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (348 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (465 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. (481 aa) |
| | ispDF | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (405 aa) |
| | glyA-2 | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (425 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (478 aa) |
| | ANL59475.1 | Ubiquinone biosynthesis hydroxylase protein; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen, flavin adenine dinucleotide binding, ubiquinone biosynthetic process and oxidation-reduction process. (403 aa) |
| | pcs | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (242 aa) |
| | ANL59572.1 | Protein involved in phosphatidylinositol phosphorylation. (275 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | trpC | Protein involved in indole-3-glycerol-phosphate synthase activity and metabolic process; Belongs to the TrpC family. (270 aa) |
| | ANL59640.1 | Citrate synthase protein; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process. (381 aa) |
| | citA | Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process; Belongs to the citrate synthase family. (362 aa) |
| | tpiA-1 | Triosephosphate isomerase 1; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (150 aa) |
| | sdaA | Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family. (467 aa) |
| | pccA | propionyl-CoA carboxylase subunit alpha; Protein involved in ATP binding, ligase activity and metabolic process. (669 aa) |
| | adhI-1 | Bifunctional alcohol dehydrogenase class 3/S-(hydroxymethyl)glutathione dehydrogenase 1; Protein involved in nucleotide binding, S-(hydroxymethyl)glutathione dehydrogenase activity, ethanol oxidation and oxidation-reduction process; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | pccB | propionyl-CoA carboxylase beta subunit; Protein involved in ligase activity. (510 aa) |
| | ANL59713.1 | Protein involved in phosphoglycolate phosphatase activity and metabolic process. (217 aa) |
| | gcvT | Protein involved in aminomethyltransferase activity and glycine catabolic process. (378 aa) |
| | gcvH | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa) |
| | gcvP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa) |
| | treS | Trehalose synthase; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process. (553 aa) |
| | rpe | D-ribulose-5 phosphate 3-epimerase; Protein involved in catalytic activity and metabolic process; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | purB | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | purC-1 | Phosphoribosylaminoimidazole-succinocarboxamide synthase 1; Protein involved in ATP binding and ligase activity; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (743 aa) |
| | icd | Isocitrate dehydrogenase (NADP(+)); Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and oxidation-reduction process; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa) |
| | ANL59817.1 | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. (249 aa) |
| | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (355 aa) |
| | ANL59829.1 | Protein involved in 3-deoxy-7-phosphoheptulonate synthase activity and aromatic amino acid family biosynthetic process. (457 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (236 aa) |
| | fumC | Fumarate hydratase class 2; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | fumA | Fumarate hydratase class 1; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (535 aa) |
| | ANL59857.1 | Transketolase C-terminal subunit protein; Protein involved in catalytic activity and metabolic process. (318 aa) |
| | ANL59858.1 | Transketolase N-terminal subunit protein. (269 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa) |
| | gnd | 6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa) |
| | cobA | uroporphyrinogen-III C-methyltransferase; Protein involved in methyltransferase activity, precorrin-2 dehydrogenase activity, metabolic process and oxidation-reduction process; Belongs to the precorrin methyltransferase family. (279 aa) |
| | ANL59990.1 | Acetyl xylan esterase protein. (319 aa) |
| | argG-1 | Protein involved in argininosuccinate synthase activity, ATP binding and arginine biosynthetic process; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (389 aa) |
| | ANL60055.1 | Ubiquinone biosynthesis family protein; Protein involved in oxidoreductase activity, transition metal ion binding, ubiquinone biosynthetic process and oxidation-reduction process; Belongs to the COQ7 family. (196 aa) |
| | dapB-2 | Dihydrodipicolinate reductase 2; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (256 aa) |
| | ribH-2 | 6,7-dimethyl-8-ribityllumazine synthase 2; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (144 aa) |
| | ANL60203.1 | Phenazine biosynthesis PhzC/PhzF-like protein; Protein involved in catalytic activity and biosynthetic process. (303 aa) |
| | ilvE | Protein involved in branched-chain-amino-acid transaminase activity and branched chain family amino acid metabolic process. (366 aa) |
| | ANL60217.1 | Myo-inositol-1-phosphate synthase protein; Protein involved in nucleotide binding, inositol biosynthetic process and phospholipid biosynthetic process. (367 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | adhC | Alcohol dehydrogenase (NADP+); Protein involved in oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups and oxidation-reduction process. (348 aa) |
| | ilvH | Acetolactate synthase 3 small subunit; Protein involved in acetolactate synthase activity and branched chain family amino acid biosynthetic process. (190 aa) |
| | ilvI | Acetolactate synthase 3 large subunit; Protein involved in magnesium ion binding, acetolactate synthase activity, thiamine pyrophosphate binding, flavin adenine dinucleotide binding and branched chain family amino acid biosynthetic process. (596 aa) |
| | dapA-2 | Dihydrodipicolinate synthase 2; Protein involved in catalytic activity and metabolic process; Belongs to the DapA family. (308 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (297 aa) |
| | ANL60274.1 | Protein involved in phosphoserine phosphatase activity and metabolic process. (296 aa) |
| | pfp | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (403 aa) |
| | ANL60364.1 | Protein involved in thiamine pyrophosphate binding; Belongs to the TPP enzyme family. (552 aa) |
| | metH | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1257 aa) |
| | aatA-1 | Aspartate aminotransferase A 1; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process. (400 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (275 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | hemF | coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (574 aa) |
| | trpE(G) | Protein involved in anthranilate synthase activity and tryptophan biosynthetic process. (729 aa) |
| | ANL60594.1 | Alpha amylase protein; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process. (548 aa) |
| | idhA-1 | Myo-inositol 2-dehydrogenase 1; Protein involved in nucleotide binding, metabolic process and oxidation-reduction process. (330 aa) |
| | ANL60726.1 | SAM-dependent methyltransferase protein. (210 aa) |
| | noeK | Phosphomannomutase; Protein involved in intramolecular transferase activity, phosphotransferases and carbohydrate metabolic process. (475 aa) |
| | noeJ | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Protein involved in nucleotidyltransferase activity and lipopolysaccharide biosynthetic process; Belongs to the mannose-6-phosphate isomerase type 2 family. (475 aa) |
| | ANL60864.1 | Short-chain dehydrogenase/reductase SDR family protein; Protein involved in nucleotide binding and metabolic process. (247 aa) |
| | purC-2 | Phosphoribosylaminoimidazole-succinocarboxamide synthase 2; Protein involved in phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, ligase activity and purine nucleotide biosynthetic process; Belongs to the SAICAR synthetase family. (314 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Protein involved in nucleotide binding, cofactor binding, L-serine biosynthetic process and oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa) |
| | ANL60990.1 | 6-phosphogluconate dehydrogenase-related protein; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process. (343 aa) |
| | cbbT | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (657 aa) |
| | gap | Glyceraldehyde 3-phosphate dehydrogenase; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, NADP binding, NAD binding and oxidation-reduction process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | pgk | Protein involved in phosphoglycerate kinase activity and glycolysis; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | ANL61003.1 | Fructose-bisphosphate aldolase protein; Protein involved in catalytic activity; Belongs to the class I fructose-bisphosphate aldolase family. (340 aa) |
| | suhB-1 | Protein involved in inositol monophosphate 1-phosphatase activity and phosphatidylinositol phosphorylation; Belongs to the inositol monophosphatase superfamily. (266 aa) |
| | ANL61022.1 | acetyl/propionyl-CoA carboxylase alpha subunit protein; Protein involved in ATP binding, ligase activity and metabolic process. (582 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | N5-carboxyaminoimidazole ribonucleotide synthetase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (358 aa) |
| | ANL61044.1 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. (324 aa) |
| | ANL61050.1 | Protein involved in pyruvate kinase activity, potassium ion binding and glycolysis; Belongs to the pyruvate kinase family. (479 aa) |
| | hss | Homospermidine synthase; Protein involved in nucleotide binding and oxidation-reduction process. (483 aa) |
| | ANL61065.1 | Protein involved in hydrolase activity and cell wall macromolecule catabolic process; Belongs to the 5'-nucleotidase family. (658 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (350 aa) |
| | exoN | UTP-glucose-1-phosphate uridylyltransferase; Protein involved in nucleotidyltransferase activity and biosynthetic process. (295 aa) |
| | gltD | Glutamate synthase (NADPH) small subunit; Protein involved in oxidoreductase activity, iron-sulfur cluster binding and oxidation-reduction process. (491 aa) |
| | gltB | Glutamate synthase (NADPH) large subunit; Protein involved in catalytic activity, oxidoreductase activity, acting on the CH-NH2 group of donors, nitrogen compound metabolic process and oxidation-reduction process. (1573 aa) |
| | ltaE | Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (350 aa) |
| | glgP | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (820 aa) |
| | glgB-1 | 1,4-alpha-glucan branching enzyme GlgB 1; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (735 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (420 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (480 aa) |
| | pgm | Phosphoglucomutase; Protein involved in intramolecular transferase activity, phosphotransferases and carbohydrate metabolic process. (543 aa) |
| | cysE-2 | Serine O-acetyltransferase 2; Protein involved in transferase activity and cysteine biosynthetic process from serine. (272 aa) |
| | ANL61145.1 | ornithine/DAP/Arg decarboxylase protein; Protein involved in catalytic activity and polyamine biosynthetic process; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (377 aa) |
| | ANL61157.1 | Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, cation binding and carbohydrate metabolic process. (459 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa) |
| | ANL61220.1 | Gluconolactonase protein. (303 aa) |
| | ANL61239.1 | Aldehyde dehydrogenase (NAD(+)) protein; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, metabolic process and oxidation-reduction process. (502 aa) |
| | lysC | Protein involved in aspartate kinase activity and lysine biosynthetic process via diaminopimelate; Belongs to the aspartokinase family. (424 aa) |
| | ubiG | Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-octaprenyl-6-hydroxyphenyl methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (248 aa) |
| | argJ | Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa) |
| | ANL61279.1 | AMP-dependent synthetase/ligase protein; Protein involved in catalytic activity and metabolic process. (543 aa) |
| | argH | Argininosuccinate lyase; Protein involved in catalytic activity and arginine biosynthetic process via ornithine. (467 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | hpt | Protein involved in hypoxanthine phosphoribosyltransferase activity and purine ribonucleoside salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | ANL61312.1 | Phospholipid/glycerol acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and metabolic process. (265 aa) |
| | tyrC | Bifunctional cyclohexadienyl dehydrogenase/prephenate dehydrogenase; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and oxidation-reduction process. (308 aa) |
| | hisC-1 | Histidinol-phosphate aminotransferase 1; Protein involved in catalytic activity, pyridoxal phosphate binding and histidine biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (196 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa) |
| | hemA-1 | 5-aminolevulinate synthase 1; Protein involved in catalytic activity, pyridoxal phosphate binding and tetrapyrrole biosynthetic process. (404 aa) |
| | arcB | Arginase; Protein involved in arginase activity, metal ion binding and arginine metabolic process; Belongs to the arginase family. (311 aa) |
| | rocD | Ornithine--oxo-acid transaminase; Protein involved in catalytic activity and pyridoxal phosphate binding; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (399 aa) |
| | ANL61442.1 | 3-oxoacyl-(acyl-carrier-protein) reductase protein; Protein involved in nucleotide binding and metabolic process. (274 aa) |
| | ANL61458.1 | Dihydrodipicolinate synthetase-like protein; Protein involved in catalytic activity and metabolic process; Belongs to the DapA family. (310 aa) |
| | ANL61464.1 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. (468 aa) |
| | sucB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (421 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component; Protein involved in oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamine pyrophosphate binding, tricarboxylic acid cycle and oxidation-reduction process. (1018 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit; Protein involved in electron carrier activity, iron-sulfur cluster binding and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (613 aa) |
| | sdhD | Protein involved in succinate dehydrogenase activity, heme binding and tricarboxylic acid cycle. (126 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 subunit; Protein involved in succinate dehydrogenase activity and tricarboxylic acid cycle. (131 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (327 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (235 aa) |
| | argG-2 | Protein involved in argininosuccinate synthase activity, ATP binding and arginine biosynthetic process; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | acnA | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (881 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (302 aa) |
| | ANL61541.1 | Chorismate mutase type II protein; Protein involved in chorismate metabolic process. (106 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | ANL61560.1 | 2-octaprenyl-6-methoxyphenyl hydroxylase protein; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen, flavin adenine dinucleotide binding, ubiquinone biosynthetic process and oxidation-reduction process. (404 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (416 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase 2; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) |
| | ANL61601.1 | Polyprenyl synthetase protein; Belongs to the FPP/GGPP synthase family. (331 aa) |
| | phbA | acetyl-CoA acetyltransferase; Protein involved in transferase activity, transferring acyl groups other than amino-acyl groups and metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | metA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa) |
| | ANL61639.1 | acyl-CoA dehydrogenase protein; Protein involved in oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, metabolic process and oxidation-reduction process. (393 aa) |
| | ANL61650.1 | Aldehyde dehydrogenase (NAD(+)) protein; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, metabolic process and oxidation-reduction process. (512 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (392 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa) |
| | ANL61686.1 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. (310 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Protein involved in catalytic activity. (538 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | ANL61721.1 | Hypothetical protein. (180 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (319 aa) |
