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| SFR31402.1 | Uridine kinase. (202 aa) | ||||
| purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa) | ||||
| ftsH | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (667 aa) | ||||
| thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (274 aa) | ||||
| SFR32742.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (191 aa) | ||||
| SFR33304.1 | Inosine-uridine nucleoside N-ribohydrolase. (302 aa) | ||||
| gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (192 aa) | ||||
| SFR35332.1 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (829 aa) | ||||
| SFR35338.1 | Ribonucleoside-diphosphate reductase beta chain. (328 aa) | ||||
| SFR35389.1 | dCMP deaminase. (150 aa) | ||||
| dut | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) | ||||
| tdk | Thymidine kinase. (215 aa) | ||||
| SFR38990.1 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (298 aa) | ||||
| SFR39136.1 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (271 aa) | ||||
| der | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa) | ||||
| SFR44998.1 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (304 aa) | ||||
| SFR45006.1 | 5'-nucleotidase, C-terminal domain. (258 aa) | ||||
| SFR47392.1 | Uridine phosphorylase. (295 aa) | ||||
| SFR48049.1 | Adenosine kinase. (327 aa) | ||||
| cmk | Cytidylate kinase. (234 aa) | ||||
| guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) | ||||
| apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) | ||||
| SFR52211.1 | Adenosine deaminase. (327 aa) | ||||
| adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (371 aa) | ||||
| SFR54496.1 | Cytidine deaminase. (160 aa) | ||||