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nadE nadE queC queC panC panC tilS tilS coaD coaD metG metG hldE hldE argG argG nadD nadD lysS lysS THII_3803 THII_3803 THII_3800 THII_3800 THII_3799 THII_3799 guaA guaA THII_3707 THII_3707 THII_3656 THII_3656 THII_3577 THII_3577 THII_3463 THII_3463 argS argS cysS cysS mnmA mnmA THII_2303 THII_2303 THII_2274 THII_2274 valS valS THII_1915 THII_1915 gltX-2 gltX-2 leuS leuS THII_1801 THII_1801 THII_1773 THII_1773 THII_1571 THII_1571 ileS ileS THII_1118 THII_1118 sat sat tyrS tyrS gltX gltX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nadENAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (663 aa)
queCExsB family protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (233 aa)
panCPantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
tilSCell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (444 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (675 aa)
hldEBifunctional protein hldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (217 aa)
lysSlysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (529 aa)
THII_3803Hypothetical protein. (502 aa)
THII_3800Electron transfer flavoprotein beta subunit. (282 aa)
THII_3799Electron transfer flavoprotein alpha subunit. (361 aa)
guaABifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. (526 aa)
THII_3707Asparagine synthase. (545 aa)
THII_3656UspA domain-containing protein. (140 aa)
THII_3577Asparagine synthase. (593 aa)
THII_3463tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (403 aa)
argSarginyl-tRNA synthetase, class Ic. (585 aa)
cysScysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (357 aa)
THII_2303Asparagine synthase, glutamine-hydrolyzing. (615 aa)
THII_2274Hypothetical protein. (614 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (920 aa)
THII_1915Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (467 aa)
gltX-2glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (469 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (813 aa)
THII_1801ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. (247 aa)
THII_1773Riboflavin biosynthesis protein ribF; Belongs to the ribF family. (308 aa)
THII_1571Osmosensitive K channel His kinase sensor. (909 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)
THII_1118Universal stress protein. (760 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (398 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (402 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (470 aa)
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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