STRINGSTRING
cph2_2 cph2_2 arlR arlR hppA hppA KRG19340.1 KRG19340.1 yfkJ yfkJ czcA_1 czcA_1 fadI fadI KRG18978.1 KRG18978.1 radA radA KRG19059.1 KRG19059.1 KRG19066.1 KRG19066.1 KRG19073.1 KRG19073.1 yycG yycG zraR_1 zraR_1 fimA fimA motA motA cph2_3 cph2_3 KRG18687.1 KRG18687.1 glnA glnA yehT yehT ypdA ypdA glnB glnB exuT exuT mnmG mnmG mnmE mnmE dnaA dnaA phrB phrB KRG18487.1 KRG18487.1 kinE_2 kinE_2 appC appC cydB cydB infB infB sauU_3 sauU_3 alsT_1 alsT_1 gltT gltT sstT_2 sstT_2 sauU_4 sauU_4 pbpE pbpE putP putP KRG18241.1 KRG18241.1 ctb ctb KRG18067.1 KRG18067.1 pilE pilE petC petC petB petB petA petA feoA feoA rpoN rpoN podJ_2 podJ_2 zraS_1 zraS_1 zraR_2 zraR_2 KRG17926.1 KRG17926.1 KRG17927.1 KRG17927.1 KRG17928.1 KRG17928.1 ywlC_1 ywlC_1 wbpI wbpI ywlC_2 ywlC_2 pleD_1 pleD_1 KRG17886.1 KRG17886.1 zraS_2 zraS_2 KRG17722.1 KRG17722.1 KRG17723.1 KRG17723.1 glsA2 glsA2 KRG17727.1 KRG17727.1 sauU_5 sauU_5 zapB zapB dusC dusC KRG17767.1 KRG17767.1 degU degU rsbP rsbP KRG17649.1 KRG17649.1 KRG17660.1 KRG17660.1 KRG17667.1 KRG17667.1 sauU_6 sauU_6 proP proP KRG17683.1 KRG17683.1 pcaF pcaF KRG17703.1 KRG17703.1 KRG17588.1 KRG17588.1 cph2_4 cph2_4 KRG17603.1 KRG17603.1 sdcS sdcS KRG17622.1 KRG17622.1 mcp4 mcp4 cheA cheA alsT_2 alsT_2 pleD_3 pleD_3 KRG17531.1 KRG17531.1 KRG17540.1 KRG17540.1 KRG17448.1 KRG17448.1 yflS yflS hda hda csrA csrA pomA_2 pomA_2 yjjL yjjL pleD_4 pleD_4 hsdM hsdM desA desA czcA_2 czcA_2 pleD_2 pleD_2 fliC fliC ntrC_1 ntrC_1 kinE_1 kinE_1 ntrC_2 ntrC_2 KRG19813.1 KRG19813.1 ylxH_1 ylxH_1 fliA fliA pomA_1 pomA_1 vanX vanX KRG19866.1 KRG19866.1 htrA_1 htrA_1 cph2_1 cph2_1 rpoE_1 rpoE_1 mscK mscK sstT_1 sstT_1 uhpC uhpC htrA_2 htrA_2 glnD glnD KRG20073.1 KRG20073.1 KRG20134.1 KRG20134.1 barA barA KRG20142.1 KRG20142.1 mucD_1 mucD_1 rpoE_2 rpoE_2 KRG20153.1 KRG20153.1 maeA maeA sauU_1 sauU_1 nhaD nhaD uvrY uvrY KRG19442.1 KRG19442.1 KRG19462.1 KRG19462.1 ctaA ctaA mucD_2 mucD_2 KRG19500.1 KRG19500.1 KRG19501.1 KRG19501.1 KRG19502.1 KRG19502.1 ccoP2 ccoP2 KRG19507.1 KRG19507.1 tolC tolC KRG19626.1 KRG19626.1 sauU_2 sauU_2 KRG19711.1 KRG19711.1 cheB cheB KRG19216.1 KRG19216.1 cheR2 cheR2 rpfC rpfC ylxH_2 ylxH_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cph2_2Phytochrome-like protein cph2. (789 aa)
arlRResponse regulator ArlR. (123 aa)
hppAK(+)-insensitive pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (693 aa)
KRG19340.1PilZ domain protein. (124 aa)
yfkJLow molecular weight protein-tyrosine-phosphatase YfkJ. (150 aa)
czcA_1Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1055 aa)
fadI3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
KRG18978.1Protein kinase domain protein. (653 aa)
radAHypothetical protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa)
KRG19059.1CAAX amino terminal protease self- immunity. (304 aa)
KRG19066.1Bacterial regulatory protein, luxR family. (289 aa)
KRG19073.1Putative DMT superfamily transporter inner membrane protein. (313 aa)
yycGSensor histidine kinase YycG. (539 aa)
zraR_1Transcriptional regulatory protein ZraR. (442 aa)
fimAFimbrial protein precursor. (131 aa)
motAMotility protein A. (295 aa)
cph2_3Phytochrome-like protein cph2. (699 aa)
KRG18687.1Aromatic amino acid exporter. (347 aa)
glnAGlutamine synthetase. (469 aa)
yehTTranscriptional regulatory protein YehT. (249 aa)
ypdASensor histidine kinase YpdA. (360 aa)
glnBNitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)
exuTHexuronate transporter. (423 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (654 aa)
mnmEtRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (443 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (460 aa)
phrBDeoxyribodipyrimidine photo-lyase; Belongs to the DNA photolyase family. (478 aa)
KRG18487.1Hypothetical protein. (408 aa)
kinE_2Sporulation kinase E. (340 aa)
appCCytochrome bd-II ubiquinol oxidase subunit 1. (471 aa)
cydBCytochrome bd-I ubiquinol oxidase subunit 2. (339 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (873 aa)
sauU_3Putative sulfoacetate transporter SauU. (445 aa)
alsT_1Amino-acid carrier protein AlsT. (467 aa)
gltTProton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (417 aa)
sstT_2Serine/threonine transporter SstT; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (404 aa)
sauU_4Putative sulfoacetate transporter SauU. (464 aa)
pbpEPenicillin-binding protein 4*. (383 aa)
putPSodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (488 aa)
KRG18241.130S ribosomal protein S1. (768 aa)
ctbGroup 3 truncated hemoglobin ctb. (129 aa)
KRG18067.1Hypothetical protein. (278 aa)
pilEFimbrial protein precursor; Belongs to the N-Me-Phe pilin family. (140 aa)
petCCytochrome c1 precursor. (263 aa)
petBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (414 aa)
petAUbiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (194 aa)
feoAFerrous iron transport protein A. (93 aa)
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (495 aa)
podJ_2Localization factor PodJL. (322 aa)
zraS_1Sensor protein ZraS. (704 aa)
zraR_2Transcriptional regulatory protein ZraR. (466 aa)
KRG17926.1Polysaccharide biosynthesis/export protein. (209 aa)
KRG17927.1Tyrosine kinase. (519 aa)
KRG17928.1Hypothetical protein. (269 aa)
ywlC_1Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (341 aa)
wbpIUDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (384 aa)
ywlC_2Threonylcarbamoyl-AMP synthase; Belongs to the SUA5 family. (202 aa)
pleD_1Response regulator PleD. (293 aa)
KRG17886.1Hypothetical protein. (545 aa)
zraS_2Sensor protein ZraS. (602 aa)
KRG17722.1PhoD-like phosphatase. (454 aa)
KRG17723.1S-adenosylmethionine/S-adenosylhomocysteine transporter. (312 aa)
glsA2Glutaminase 2; Belongs to the glutaminase family. (322 aa)
KRG17727.1Hypothetical protein. (251 aa)
sauU_5Putative sulfoacetate transporter SauU. (435 aa)
zapBCell division protein ZapB. (84 aa)
dusCtRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (340 aa)
KRG17767.1Sulfite exporter TauE/SafE. (268 aa)
degUTranscriptional regulatory protein DegU. (242 aa)
rsbPPhosphoserine phosphatase RsbP. (406 aa)
KRG17649.1Hypothetical protein. (437 aa)
KRG17660.1M61 glycyl aminopeptidase. (597 aa)
KRG17667.1Outer membrane efflux protein. (475 aa)
sauU_6Putative sulfoacetate transporter SauU. (424 aa)
proPProline/betaine transporter. (432 aa)
KRG17683.1Hypothetical protein. (373 aa)
pcaFBeta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (436 aa)
KRG17703.1Hypothetical protein. (181 aa)
KRG17588.1Blue-light-activated protein. (1001 aa)
cph2_4Phytochrome-like protein cph2. (389 aa)
KRG17603.1Hypothetical protein. (432 aa)
sdcSSodium-dependent dicarboxylate transporter SdcS. (613 aa)
KRG17622.1CheW-like domain protein. (209 aa)
mcp4Methyl-accepting chemotaxis protein 4. (434 aa)
cheAChemotaxis protein CheA. (604 aa)
alsT_2Amino-acid carrier protein AlsT. (456 aa)
pleD_3Response regulator PleD. (353 aa)
KRG17531.1HDOD domain protein. (280 aa)
KRG17540.1Hypothetical protein. (545 aa)
KRG17448.1Helix-turn-helix protein. (112 aa)
yflSPutative malate transporter YflS. (480 aa)
hdaDnaA regulatory inactivator Hda; Belongs to the DnaA family. HdA subfamily. (233 aa)
csrAHypothetical protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (69 aa)
pomA_2Chemotaxis protein PomA. (254 aa)
yjjLL-galactonate transporter. (439 aa)
pleD_4Response regulator PleD. (510 aa)
hsdMType I restriction enzyme EcoKI M protein. (544 aa)
desADelta(12)-fatty-acid desaturase. (361 aa)
czcA_2Cobalt-zinc-cadmium resistance protein CzcA. (72 aa)
pleD_2Response regulator PleD. (551 aa)
fliCA-type flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (753 aa)
ntrC_1Nitrogen assimilation regulatory protein. (347 aa)
kinE_1Sporulation kinase E. (357 aa)
ntrC_2Nitrogen assimilation regulatory protein. (445 aa)
KRG19813.1Hypothetical protein. (101 aa)
ylxH_1Flagellum site-determining protein YlxH. (284 aa)
fliARNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (240 aa)
pomA_1Chemotaxis protein PomA. (253 aa)
vanXD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (214 aa)
KRG19866.1EamA-like transporter family protein. (306 aa)
htrA_1Serine protease Do-like HtrA. (522 aa)
cph2_1Phytochrome-like protein cph2. (589 aa)
rpoE_1ECF RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
mscKMechanosensitive channel MscK precursor. (771 aa)
sstT_1Serine/threonine transporter SstT; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (406 aa)
uhpCRegulatory protein UhpC. (460 aa)
htrA_2Serine protease Do-like HtrA. (564 aa)
glnDBifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (894 aa)
KRG20073.1Transposase zinc-ribbon domain protein. (322 aa)
KRG20134.1ABC transporter substrate binding protein. (332 aa)
barASignal transduction histidine-protein kinase BarA. (944 aa)
KRG20142.1Hypothetical protein. (119 aa)
mucD_1Putative periplasmic serine endoprotease DegP-like precursor; Belongs to the peptidase S1C family. (482 aa)
rpoE_2ECF RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
KRG20153.1HDOD domain protein. (279 aa)
maeAPutative NAD-dependent malic enzyme 2. (580 aa)
sauU_1Putative sulfoacetate transporter SauU. (429 aa)
nhaDNa(+)/H(+) antiporter NhaD. (483 aa)
uvrYResponse regulator UvrY. (222 aa)
KRG19442.1FtsX-like permease family protein. (823 aa)
KRG19462.1EamA-like transporter family protein. (313 aa)
ctaAHeme A synthase. (338 aa)
mucD_2Putative periplasmic serine endoprotease DegP-like precursor. (404 aa)
KRG19500.1Hypothetical protein; Cytochrome c oxidase subunit 1, bacteroid; Belongs to the heme-copper respiratory oxidase family. (496 aa)
KRG19501.1Cytochrome C oxidase, mono-heme subunit/FixO. (203 aa)
KRG19502.1Cbb3-type cytochrome oxidase component FixQ. (58 aa)
ccoP2Cbb3-type cytochrome c oxidase subunit CcoP2; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (300 aa)
KRG19507.1Cytochrome oxidase maturation protein cbb3-type. (58 aa)
tolCOuter membrane protein TolC precursor. (432 aa)
KRG19626.1Putative acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
sauU_2Putative sulfoacetate transporter SauU. (424 aa)
KRG19711.1Hypothetical protein. (257 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase. (196 aa)
KRG19216.1Blue-light-activated protein. (651 aa)
cheR2Chemotaxis protein methyltransferase Cher2. (277 aa)
rpfCSensory/regulatory protein RpfC. (1218 aa)
ylxH_2Flagellum site-determining protein YlxH; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (365 aa)
Your Current Organism:
Berkiella cookevillensis
NCBI taxonomy Id: 437022
Other names: C. Berkiella cookevillensis, Candidatus Berkiella cookevillensis, Coxiellaceae bacterium CC99, Legionella-like amoebal pathogen CC99
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