STRINGSTRING
ABZ97236.1 ABZ97236.1 ABZ97173.1 ABZ97173.1 ABZ97127.1 ABZ97127.1 ABZ97105.1 ABZ97105.1 lpxK lpxK ugd ugd ABZ97003.1 ABZ97003.1 ABZ96940.1 ABZ96940.1 ABZ96863.1 ABZ96863.1 ABZ96828.1 ABZ96828.1 lpxD2 lpxD2 ABZ96694.1 ABZ96694.1 ABZ96679.1 ABZ96679.1 rfbA rfbA ABZ96631.1 ABZ96631.1 manC manC ABZ96605.1 ABZ96605.1 ABZ96522.1 ABZ96522.1 lpxA lpxA algI algI ABZ96401.1 ABZ96401.1 ABZ96391.1 ABZ96391.1 glmU glmU kdsB kdsB ABZ96322.1 ABZ96322.1 pgi pgi ABZ96184.1 ABZ96184.1 algI-2 algI-2 ABZ99790.1 ABZ99790.1 ABZ99789.1 ABZ99789.1 capD capD ABZ99659.1 ABZ99659.1 ABZ99567.1 ABZ99567.1 ABZ99388.1 ABZ99388.1 ABZ99336.1 ABZ99336.1 ABZ99264.1 ABZ99264.1 ABZ99162.1 ABZ99162.1 glgA glgA pck pck algI3 algI3 ABZ98967.1 ABZ98967.1 ABZ98932.1 ABZ98932.1 ABZ98716.1 ABZ98716.1 tpsA tpsA lpxD lpxD dkgA dkgA ABZ98415.1 ABZ98415.1 ABZ98374.1 ABZ98374.1 ABZ98246.1 ABZ98246.1 tpiA tpiA lpxB lpxB ABZ98163.1 ABZ98163.1 ABZ98144.1 ABZ98144.1 rmlA rmlA ABZ98139.1 ABZ98139.1 ABZ98138.1 ABZ98138.1 ABZ98129.1 ABZ98129.1 ABZ98126.1 ABZ98126.1 ABZ98117.1 ABZ98117.1 ABZ98114.1 ABZ98114.1 ABZ98110.1 ABZ98110.1 ABZ98106.1 ABZ98106.1 glf glf ABZ98094.1 ABZ98094.1 ABZ98087.1 ABZ98087.1 glgC glgC lpxC lpxC ABZ97924.1 ABZ97924.1 ABZ97895.1 ABZ97895.1 ABZ97838.1 ABZ97838.1 kdsA kdsA fbp fbp ABZ97524.1 ABZ97524.1 ABZ97476.1 ABZ97476.1 ABZ97472.1 ABZ97472.1 ABZ97442.1 ABZ97442.1 ABZ97197.1 ABZ97197.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABZ97236.1Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (370 aa)
ABZ97173.1Putative pyridoxal-phosphate-dependent aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (373 aa)
ABZ97127.1Putative lipopolysaccharide core biosynthesis glycosyl transferase RfaQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (351 aa)
ABZ97105.1Hypothetical protein; No homology to any previously reported sequences. (487 aa)
lpxKPutative tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (374 aa)
ugdUDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (434 aa)
ABZ97003.1Putative N-acylneuraminate-9-phosphate synthase; N-acetylneuraminate 9-phosphate lyase; N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase; N-acetylneuraminate 9-phosphate synthetase; N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating); Sialic acid 9-phosphate synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (330 aa)
ABZ96940.1Putative acyltransferase, MBOAT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (465 aa)
ABZ96863.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (327 aa)
ABZ96828.1Putative aminotransferase, DegT/DnrJ/EryC1/StrS family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (364 aa)
lpxD2UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa)
ABZ96694.1Putative phosphoglycerol transferase, alkaline phosphatase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (666 aa)
ABZ96679.1Putative alginate o-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (492 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (343 aa)
ABZ96631.1Putative polyglutamyl synthetase, CapC family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (154 aa)
manCMannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (356 aa)
ABZ96605.1Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (403 aa)
ABZ96522.1ABC-type transport system, permease, putative copper ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (422 aa)
lpxAAcyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (268 aa)
algIPutative poly(beta-D-mannuronate) O-acetylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (518 aa)
ABZ96401.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (584 aa)
ABZ96391.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (283 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (253 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (246 aa)
ABZ96322.1Putative alginate O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the membrane-bound acyltransferase family. (460 aa)
pgiGPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (450 aa)
ABZ96184.1Conserved hypothetical protein, putative transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (399 aa)
algI-2Alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (492 aa)
ABZ99790.1Putative alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (498 aa)
ABZ99789.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (428 aa)
capDCapsular polysaccharide biosynthesis protein; Function of homologous gene experimentally demonstrated in an other organism; factor. (658 aa)
ABZ99659.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (404 aa)
ABZ99567.1Hypothetical protein; No homology to any previously reported sequences; putative membrane component. (358 aa)
ABZ99388.1Putative arylesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (346 aa)
ABZ99336.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (477 aa)
ABZ99264.1Conserved hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (425 aa)
ABZ99162.1Putative membrane bound 0-acyl transferase, putative alginate biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the membrane-bound acyltransferase family. (456 aa)
glgAPutative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (476 aa)
pckPhosphoenolpyruvate carboxykinase [ATP] (PEP carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
algI3Alginate O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the membrane-bound acyltransferase family. (488 aa)
ABZ98967.1Hypothetical protein; No homology to any previously reported sequences. (537 aa)
ABZ98932.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (424 aa)
ABZ98716.1Putative strictosidine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (346 aa)
tpsATrehalose-6-phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (730 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (339 aa)
dkgA2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (275 aa)
ABZ98415.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (522 aa)
ABZ98374.1Putative glycosyl transferase, family 39; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (539 aa)
ABZ98246.1Putative glycoside hydrolase, family 57; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 57 family. (528 aa)
tpiATriosephosphate isomerase (TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
lpxBLipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (372 aa)
ABZ98163.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (288 aa)
ABZ98144.1Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (698 aa)
rmlAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
ABZ98139.1Putative UDP-glucose 4-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (335 aa)
ABZ98138.1Putative pyridoxal-phosphate-dependent aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (386 aa)
ABZ98129.1Putative N-acetylneuraminic acid (Neu5Ac) synthase, NeuB family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (348 aa)
ABZ98126.1Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (424 aa)
ABZ98117.1Hypothetical protein; No homology to any previously reported sequences. (570 aa)
ABZ98114.1Putative pyridoxal-phosphate-dependent aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. (370 aa)
ABZ98110.1Putative poly(beta-D-mannuronate) O-acetylase (Alginate biosynthesis protein AlgI); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (291 aa)
ABZ98106.1Hypothetical protein; No homology to any previously reported sequences; putative membrane component. (427 aa)
glfUDP-galactopyranose mutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (374 aa)
ABZ98094.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (467 aa)
ABZ98087.1Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (490 aa)
glgCGlucose-1-phosphate adenylyltransferase small subunit; ADP-glucose synthase; ADP-glucose pyrophosphorylase; AGPASE B; Alpha-D-glucose-1-phosphate adenyl transferase; ADPGlc PPase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (427 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (302 aa)
ABZ97924.1Putative poly(beta-D-mannuronate) O-acetylase (Alginate biosynthesis protein AlgI); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the membrane-bound acyltransferase family. (474 aa)
ABZ97895.1Putative ADP-heptose:LPS heptosyltransferase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (353 aa)
ABZ97838.1Putative undecaprenyl-phosphate galactose phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (466 aa)
kdsAPhospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; (KDOPS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. (281 aa)
fbpFructose-1,6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (383 aa)
ABZ97524.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (633 aa)
ABZ97476.1Putative dolichyl-phosphate-mannose--protein mannosyltransferase protein, family 39; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (568 aa)
ABZ97472.1Putative alkaline phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (664 aa)
ABZ97442.1Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)
ABZ97197.1Putative membrane-bound phosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (399 aa)
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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