STRINGSTRING
pntA pntA htpG htpG ompL1 ompL1 galE galE lpxA lpxA lntA lntA lpxK lpxK sucA sucA gmhA gmhA lpxC lpxC kdsA kdsA tpiA tpiA rpsF rpsF clpB clpB flhB flhB lntB lntB flgK flgK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pntAPyridine nucleotide transhydrogenase subunit alpha 1; Nicotinamide nucleotide transhydrogenase subunit alpha 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (375 aa)
htpGHeat shock protein HtpG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor. (610 aa)
ompL1Outer membrane protein OmpL1; Function of homologous gene experimentally demonstrated in an other organism; membrane component. (300 aa)
galEUDP-glucose 4-epimerase (Galactowaldenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (322 aa)
lpxAAcyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (268 aa)
lntAApolipoprotein N-acyltransferase 1 (ALP N-acyltransferase 1); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (515 aa)
lpxKPutative tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (374 aa)
sucA2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (922 aa)
gmhAPhosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (195 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (302 aa)
kdsAPhospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; (KDOPS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. (281 aa)
tpiATriosephosphate isomerase (TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (91 aa)
clpBChaperone ClpB; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family. (795 aa)
flhBFlagellar biosynthetic protein FlhB; Function of homologous gene experimentally demonstrated in an other organism; structure. (403 aa)
lntBApolipoprotein N-acyltransferase 2 (ALP N-acyltransferase 2); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (587 aa)
flgKFlagellar hook-associated protein 1 (HAP1); Function of homologous gene experimentally demonstrated in an other organism; structure. (637 aa)
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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