(39 nodes) Pigment cell differentiation network (Neogobius melanostomus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSNMLP00000042542	Cadherin 2, type 1, N-cadherin (neuronal). (558 aa)
	ENSNMLP00000040404	Tyrosinase-related protein 1a. (522 aa)
	ENSNMLP00000037436	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (579 aa)
	ENSNMLP00000036459	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (681 aa)
	ENSNMLP00000036055	Dopachrome tautomerase. (514 aa)
	ENSNMLP00000033105	CD63 molecule. (240 aa)
	ENSNMLP00000031952	Tyrosinase-related protein 1b. (518 aa)
	ENSNMLP00000031828	Endothelin receptor type Bb. (428 aa)
	RAB38	RAB38, member RAS oncogene family. (212 aa)
	ENSNMLP00000001722	Biogenesis of lysosomal organelles complex-1, subunit 3. (213 aa)
	ENSNMLP00000002786	Zgc:162171. (223 aa)
	ENSNMLP00000002822	annotation not available (69 aa)
	ENSNMLP00000003708	Transcription factor AP-2 epsilon. (402 aa)
	ENSNMLP00000003788	Endothelin receptor Ba. (417 aa)
	ENSNMLP00000005649	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin. (75 aa)
	ENSNMLP00000006249	RIC8 guanine nucleotide exchange factor B. (490 aa)
	ENSNMLP00000006468	RAB32a, member RAS oncogene family. (213 aa)
	ENSNMLP00000009902	RAB38b, member of RAS oncogene family. (219 aa)
	ENSNMLP00000010590	annotation not available (411 aa)
	ENSNMLP00000011189	Zgc:162171. (229 aa)
	HPS6	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3. (729 aa)
	ENSNMLP00000017927	Mitochondrial inner membrane protein MPV17. (177 aa)
	ENSNMLP00000019109	Biogenesis of lysosomal organelles complex-1, subunit 5, muted. (153 aa)
	ENSNMLP00000019367	Oculocutaneous albinism II. (831 aa)
	ENSNMLP00000019426	Presenilin 1. (437 aa)
	ENSNMLP00000019688	Solute carrier family 24 member 5. (498 aa)
	ENSNMLP00000020174	annotation not available (215 aa)
	ENSNMLP00000020496	Ring finger protein 41. (318 aa)
	ENSNMLP00000021442	Presenilin 2. (441 aa)
	ENSNMLP00000023598	RAB38c, member of RAS oncogene family. (222 aa)
	ENSNMLP00000023715	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (200 aa)
	ENSNMLP00000024830	LEO1 homolog, Paf1/RNA polymerase II complex component. (693 aa)
	ENSNMLP00000025779	Leucine rich melanocyte differentiation associated. (222 aa)
	ENSNMLP00000026835	Ankyrin repeat domain 27 (VPS9 domain). (1115 aa)
	ENSNMLP00000027276	Tyrosinase. (540 aa)
	ENSNMLP00000044207	Mindbomb E3 ubiquitin protein ligase 1. (1009 aa)
	ENSNMLP00000043705	VPS18 core subunit of CORVET and HOPS complexes. (986 aa)
	CDH2	Cadherin 2. (903 aa)
	ENSNMLP00000042551	annotation not available (175 aa)

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	ENSNMLP00000042542	ENSNMLP00000042579	ENSNMLP00000042542	Cadherin 2.	Cadherin 2, type 1, N-cadherin (neuronal).	0.821
ENSNMLP00000001722	ENSNMLP00000005649	ENSNMLP00000001722	ENSNMLP00000005649	Biogenesis of lysosomal organelles complex-1, subunit 3.	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	0.978
ENSNMLP00000001722	ENSNMLP00000019109	ENSNMLP00000001722	ENSNMLP00000019109	Biogenesis of lysosomal organelles complex-1, subunit 3.	Biogenesis of lysosomal organelles complex-1, subunit 5, muted.	0.973
ENSNMLP00000001722	ENSNMLP00000036459	ENSNMLP00000001722	ENSNMLP00000036459	Biogenesis of lysosomal organelles complex-1, subunit 3.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.864
ENSNMLP00000001722	ENSNMLP00000037436	ENSNMLP00000001722	ENSNMLP00000037436	Biogenesis of lysosomal organelles complex-1, subunit 3.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.918
ENSNMLP00000001722	HPS6	ENSNMLP00000001722	ENSNMLP00000011379	Biogenesis of lysosomal organelles complex-1, subunit 3.	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.	0.929
ENSNMLP00000002786	ENSNMLP00000026835	ENSNMLP00000002786	ENSNMLP00000026835	Zgc:162171.	Ankyrin repeat domain 27 (VPS9 domain).	0.723
ENSNMLP00000002786	ENSNMLP00000036459	ENSNMLP00000002786	ENSNMLP00000036459	Zgc:162171.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.545
ENSNMLP00000002786	ENSNMLP00000037436	ENSNMLP00000002786	ENSNMLP00000037436	Zgc:162171.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.407
ENSNMLP00000002822	ENSNMLP00000026835	ENSNMLP00000002822	ENSNMLP00000026835	annotation not available	Ankyrin repeat domain 27 (VPS9 domain).	0.723
ENSNMLP00000002822	ENSNMLP00000036459	ENSNMLP00000002822	ENSNMLP00000036459	annotation not available	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.545
ENSNMLP00000002822	ENSNMLP00000037436	ENSNMLP00000002822	ENSNMLP00000037436	annotation not available	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.407
ENSNMLP00000003708	ENSNMLP00000023715	ENSNMLP00000003708	ENSNMLP00000023715	Transcription factor AP-2 epsilon.	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1.	0.453
ENSNMLP00000003788	ENSNMLP00000010590	ENSNMLP00000003788	ENSNMLP00000010590	Endothelin receptor Ba.	annotation not available	0.822
ENSNMLP00000005649	ENSNMLP00000001722	ENSNMLP00000005649	ENSNMLP00000001722	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	Biogenesis of lysosomal organelles complex-1, subunit 3.	0.978
ENSNMLP00000005649	ENSNMLP00000019109	ENSNMLP00000005649	ENSNMLP00000019109	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	Biogenesis of lysosomal organelles complex-1, subunit 5, muted.	0.978
ENSNMLP00000005649	ENSNMLP00000036459	ENSNMLP00000005649	ENSNMLP00000036459	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.890
ENSNMLP00000005649	ENSNMLP00000037436	ENSNMLP00000005649	ENSNMLP00000037436	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.921
ENSNMLP00000005649	HPS6	ENSNMLP00000005649	ENSNMLP00000011379	Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin.	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.	0.929
ENSNMLP00000006468	ENSNMLP00000026835	ENSNMLP00000006468	ENSNMLP00000026835	RAB32a, member RAS oncogene family.	Ankyrin repeat domain 27 (VPS9 domain).	0.723